{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:33:37Z","timestamp":1786649617991,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction and Aim:<\/jats:title>\n                    <jats:p>Middle ear surgeries can be performed under local anesthesia and sedation and can be well tolerated by the patient with minimal discomfort. This study was undertaken to compare two techniques of conscious sedation, intravenous midazolam, and propofol infusion for tympanoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Forty patients scheduled for right or left tympanoplasty. American Society of Anesthesiologists I or II in age group 18-75 years were included in the study. The patients were randomly allocated into one of the two groups to receive either propofol (group I) or midazolam (group II).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean duration of anesthesia was 116.00 \u00b1 33.94 min in group I, while 97.50 \u00b1 30.76 min in group II (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.07). The modified Ramsay sedation scale was not statistically significant in both the groups. In group I, 70% of the patients and 95% of the patients in group II had amnesia during the surgery (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.091). The mean visual analog scale (VAS) score for surgeons and patients was not statistically significant in both the groups. In group I there was a positive correlation between the total dose of fentanyl and VAS score for surgeons (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.02). There was also a positive correlation between the total dose of propofol and VAS score for surgeons (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.034) and patients (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.039) in group I.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Though propofol had shown a faster recovery and less nausea vomiting, we need a larger sample size to conclude, which of the technique is better. Both the techniques are safe, simple and versatile and provide excellent sedation with rapid trouble free recovery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/1658-354x.152818","type":"journal-article","created":{"date-parts":[[2015,3,9]],"date-time":"2015-03-09T07:49:48Z","timestamp":1425887388000},"page":"117-121","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Conscious sedation for middle ear surgeries: A comparison between fentanyl-propofol and fentanyl-midazolam infusion"],"prefix":"10.4103","volume":"9","author":[{"given":"Raghu S.","family":"Thota","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Centre, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manasi","family":"Ambardekar","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyamvada","family":"Likhate","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Centre, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-20251006","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.anclin.2010.07.009","article-title":"Review of anesthesia for middle ear surgery","volume":"28","author":"Liang","year":"2010","journal-title":"Anesthesiol Clin"},{"key":"R3-20251006","first-page":"1226","article-title":"Aspects of anesthesia for middle ear surgery an blood loss during stapedectomy","volume":"64","author":"Deacock","year":"1971","journal-title":"Proc R Soc Med"},{"key":"R5-20251006","first-page":"487","article-title":"Sedation for middle ear surgery: Prospective clinical trial comparing propofol and 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sedation","volume":"42","author":"Mackenzie","year":"1987","journal-title":"Anesthesia"},{"key":"R14-20251006","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1046\/j.1365-2273.1996.00814.x","article-title":"Local anesthesia in middle ear surgery: Survey of patients and surgeons","volume":"21","author":"Yung","year":"1996","journal-title":"Clin Otolaryngol Allied Sci"}],"container-title":["Saudi Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01437113-201509020-00002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:56:08Z","timestamp":1786647368000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01437113-201509020-00002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.4103\/1658-354x.152818","relation":{},"ISSN":["1658-354X","0975-3125"],"issn-type":[{"value":"1658-354X","type":"print"},{"value":"0975-3125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4]]}}}