{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T14:30:53Z","timestamp":1786717853968,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neural Regen Res"],"published-print":{"date-parts":[[2016]]},"DOI":"10.4103\/1673-5374.193227","type":"journal-article","created":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T08:05:17Z","timestamp":1477641917000},"page":"1564","source":"Crossref","is-referenced-by-count":4,"title":["Valproic acid as a microRNA modulator to promote neurite outgrowth"],"prefix":"10.4103","volume":"11","author":[{"given":"JudyC. G.","family":"Sng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Oikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/1673-5374.193227-1","doi-asserted-by":"crossref","unstructured":"Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G (2005) REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 121:645-657.","DOI":"10.1016\/j.cell.2005.03.013"},{"key":"key-10.4103\/1673-5374.193227-2","doi-asserted-by":"crossref","unstructured":"Chwang WB, Arthur JS, Schumacher A, Sweatt JD (2007) The nuclear kinase mitogen- and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation. J Neurosci 27:12732-12742.","DOI":"10.1523\/JNEUROSCI.2522-07.2007"},{"key":"key-10.4103\/1673-5374.193227-3","doi-asserted-by":"crossref","unstructured":"Fiore R, Khudayberdiey S, Saba R, Schrtt G (2011) MicroRNA function in the nervous system. Prog Mol Biol Transl Sci 102:47-100.","DOI":"10.1016\/B978-0-12-415795-8.00004-0"},{"key":"key-10.4103\/1673-5374.193227-4","doi-asserted-by":"crossref","unstructured":"Foti SB, Chou A, Moll AD, Roskams AJ (2013) HDAC inhibitors dysregulate neural stem cell activity in the postnatal mouse brain. Int J Dev Neurosci 31:434-447.","DOI":"10.1016\/j.ijdevneu.2013.03.008"},{"key":"key-10.4103\/1673-5374.193227-5","doi-asserted-by":"crossref","unstructured":"Goh WW, Oikawa H, Sng JC, Sergot M, Wong L (2012) The role of miRNAs in complex formation and control. Bioinformatics 28:453-456.","DOI":"10.1093\/bioinformatics\/btr693"},{"key":"key-10.4103\/1673-5374.193227-6","unstructured":"Hunsberger JG, Fessler EB, Wang Z, Elkahloun AG, Chuang DM (2012) Postinsultvalproic acid-regulated microRNAs potential targets for cerebral ischemia. Am J Transl Res 4:316-332."},{"key":"key-10.4103\/1673-5374.193227-7","doi-asserted-by":"crossref","unstructured":"Jessberger S, Nakashima K, Clemenson GD Jr, Mejia E, Mathews E, Ure K, Ogawa S, Sinton CM, Gage FH, Hsieh J (2007) Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. J Neurosci 27:5967-5975.","DOI":"10.1523\/JNEUROSCI.0110-07.2007"},{"key":"key-10.4103\/1673-5374.193227-8","doi-asserted-by":"crossref","unstructured":"Lubin FD, Sweatt JD (2007) The IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories. Neuron 55:942-952.","DOI":"10.1016\/j.neuron.2007.07.039"},{"key":"key-10.4103\/1673-5374.193227-9","doi-asserted-by":"crossref","unstructured":"Nishino S, Ohtomo K, Numata Y, Sato T, Nakahata N, Kurita M (2012) Divergent effects of lithium and sodium valproate on brain-derived neurotrophic factor (BDNF) production in human astrocytoma cells at therapeutic concentrations. Prog Neuropsychopharmacol Biol Psychiatry 39:17-22.","DOI":"10.1016\/j.pnpbp.2011.07.008"},{"key":"key-10.4103\/1673-5374.193227-10","doi-asserted-by":"crossref","unstructured":"Oikawa H, Goh WW, Lim VK, Wong L, Sng JC (2015) Valproic acid mediates miR-124 to down-regulate a novel protein target, GNAI1. Neurochem Int 91: 62-71.","DOI":"10.1016\/j.neuint.2015.10.010"},{"key":"key-10.4103\/1673-5374.193227-11","doi-asserted-by":"crossref","unstructured":"Wayman GA, Davare M, Ando H, Fortin D, Varlamova O, Cheng HY, Marks D, Obrietan K, Soderling TR, Goodman RH, Impey S (2008) An activity-regulated microRNA controls dendritic plasticity by downregulating p250GAP. Proc Natl Acad Sci U S A 105:9093-9098.","DOI":"10.1073\/pnas.0803072105"},{"key":"key-10.4103\/1673-5374.193227-12","doi-asserted-by":"crossref","unstructured":"Yu JY, Chung KH, Deo M, Thompson RC, Turner DL (2008) MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation. Exp Cell Res 314:2618-2633.","DOI":"10.1016\/j.yexcr.2008.06.002"}],"container-title":["Neural Regeneration Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:28:46Z","timestamp":1786714126000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1673-5374.193227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":12,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016]]}},"alternative-id":["193227"],"URL":"https:\/\/doi.org\/10.4103\/1673-5374.193227","relation":{},"ISSN":["1673-5374"],"issn-type":[{"value":"1673-5374","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}