{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T22:37:09Z","timestamp":1792708629676,"version":"4.5.0"},"reference-count":153,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cerebral palsy is a diagnostic term utilized to describe a group of permanent disorders affecting movement and posture. Patients with cerebral palsy are often only capable of limited activity, resulting from non-progressive disturbances in the fetal or neonatal brain. These disturbances severely impact the child's daily life and impose a substantial economic burden on the family. Although cerebral palsy encompasses various brain injuries leading to similar clinical outcomes, the understanding of its etiological pathways remains incomplete owing to its complexity and heterogeneity. This review aims to summarize the current knowledge on the genetic factors influencing cerebral palsy development. It is now widely acknowledged that genetic mutations and alterations play a pivotal role in cerebral palsy development, which can be further influenced by environmental factors. Despite continuous research endeavors, the underlying factors contributing to cerebral palsy remain are still elusive. However, significant progress has been made in genetic research that has markedly enhanced our comprehension of the genetic factors underlying cerebral palsy development. Moreover, these genetic factors have been categorized based on the identified gene mutations in patients through clinical genotyping, including thrombosis, angiogenesis, mitochondrial and oxidative phosphorylation function, neuronal migration, and cellular autophagy. Furthermore, exploring targeted genotypes holds potential for precision treatment. In conclusion, advancements in genetic research have substantially improved our understanding of the genetic causes underlying cerebral palsy. These breakthroughs have the potential to pave the way for new treatments and therapies, consequently shaping the future of cerebral palsy research and its clinical management. The investigation of cerebral palsy genetics holds the potential to significantly advance treatments and management strategies. By elucidating the underlying cellular mechanisms, we can develop targeted interventions to optimize outcomes. A continued collaboration between researchers and clinicians is imperative to comprehensively unravel the intricate genetic etiology of cerebral palsy.<\/jats:p>","DOI":"10.4103\/1673-5374.385855","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T00:01:16Z","timestamp":1695600076000},"page":"1499-1508","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":16,"title":["Genetic pathways in cerebral palsy: a review of the implications for precision diagnosis and understanding disease mechanisms"],"prefix":"10.4103","volume":"19","author":[{"given":"Yiran","family":"Xu","sequence":"first","affiliation":[{"name":"Henan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Institute of Neuroscience and The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China"},{"name":"National Health Council (NHC) Key Laboratory of Birth Defects Prevention, Henan Key Laboratory of Population Defects Prevention, Zhengzhou, Henan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Human Anatomy, School of Basic Medicine and Institute of Neuroscience, Zhengzhou University, Zhengzhou, Henan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seidu A.","family":"Richard","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Institute of Neuroscience and The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0378-823X","authenticated-orcid":false,"given":"Yanyan","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Human Anatomy, School of Basic Medicine and Institute of Neuroscience, Zhengzhou University, Zhengzhou, Henan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5029-6730","authenticated-orcid":false,"given":"Changlian","family":"Zhu","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, Institute of Neuroscience and The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China"},{"name":"Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,9,22]]},"reference":[{"key":"R1-20260511","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s12881-019-0924-6","article-title":"Effects of factor v Leiden polymorphism on the pathogenesis and outcomes of preeclampsia","volume":"20","author":"Ababio","year":"2019","journal-title":"BMC Med Genet"},{"key":"R2-20260511","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1002\/ajmg.a.62138","article-title":"Whole genome sequencing of 45 Japanese patients with intellectual disability","volume":"185","author":"Abe-Hatano","year":"2021","journal-title":"Am J Med Genet A"},{"key":"R3-20260511","first-page":"51","article-title":"Developmental and perinatal brain diseases","volume":"145","author":"Adle-Biassette","year":"2017","journal-title":"Handb Clin Neurol"},{"key":"R4-20260511","doi-asserted-by":"crossref","first-page":"48562","DOI":"10.1074\/jbc.M406649200","article-title":"The human FA2H gene encodes a fatty acid 2-hydroxylase","volume":"279","author":"Alderson","year":"2004","journal-title":"J Biol Chem"},{"key":"R5-20260511","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1089\/gtmb.2012.0017","article-title":"Leiden V factor and spastic cerebral palsy in Mexican children","volume":"16","author":"Arenas-Sordo Mde","year":"2012","journal-title":"Genet Test Mol Biomarkers"},{"key":"R6-20260511","first-page":"385","article-title":"Preeclampsia and cerebral palsy in offspring","volume":"9","author":"Badagionis","year":"2022","journal-title":"Children (Basel)"},{"key":"R7-20260511","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1136\/bmj.2.4932.163","article-title":"Problems in the classification of cerebral palsy in childhood","volume":"2","author":"Balf","year":"1955","journal-title":"Br Med J"},{"key":"R8-20260511","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1469-8749.1964.tb10791.x","article-title":"Terminology and classification of cerebral palsy","volume":"6","author":"Bax","year":"1964","journal-title":"Dev Med Child Neurol"},{"key":"R9-20260511","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.pediatrneurol.2015.12.018","article-title":"Maternal infections during pregnancy and cerebral palsy in the child","volume":"57","author":"Bear","year":"2016","journal-title":"Pediatr Neurol"},{"key":"R10-20260511","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1471-4159.2004.02501.x","article-title":"Mammalian central nervous system trace amines","volume":"90","author":"Berry","year":"2004","journal-title":"J Neurochem"},{"key":"R11-20260511","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1136\/jech.50.5.559","article-title":"The undesirable consequences of controlling for birth weight in perinatal epidemiological studies","volume":"50","author":"Blair","year":"1996","journal-title":"J Epidemiol Community Health"},{"key":"R12-20260511","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1007\/s00415-021-10507-8","article-title":"Neurophysiological and ophthalmological findings of SPG7-related spastic ataxia: a phenotype study in an Irish cohort","volume":"268","author":"Bogdanova-Mihaylova","year":"2021","journal-title":"J Neurol"},{"key":"R13-20260511","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/j.1469-8749.2009.03465.x","article-title":"Apolipoprotein E genotype and cerebral palsy","volume":"52","author":"Braga","year":"2010","journal-title":"Dev Med Child Neurol"},{"key":"R14-20260511","first-page":"223","article-title":"Does infection during pregnancy outside of the time of delivery increase the risk of cerebral palsy?","volume":"34","author":"Brookfield","year":"2017","journal-title":"Am J Perinatol"},{"key":"R15-20260511","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.jpeds.2011.05.042","article-title":"Cytokines and neurodevelopmental outcomes in extremely low birth weight infants","volume":"159","author":"Carlo","year":"2011","journal-title":"J Pediatr"},{"key":"R16-20260511","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1001\/jamapediatrics.2016.1936","article-title":"Association of neurodevelopmental outcomes and neonatal morbidities of extremely premature infants with differential exposure to antenatal steroids","volume":"170","author":"Chawla","year":"2016","journal-title":"JAMA Pediatr"},{"key":"R17-20260511","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/jhg.2010.127","article-title":"Methylenetetrahydrofolate reductase gene polymorphisms and cerebral palsy in Chinese infants","volume":"56","author":"Cheng","year":"2011","journal-title":"J Hum Genet"},{"key":"R18-20260511","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/acn3.51506","article-title":"Mendelian etiologies identified with whole exome sequencing in cerebral palsy","volume":"9","author":"Chopra","year":"2022","journal-title":"Ann Clin Transl Neurol"},{"key":"R19-20260511","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/dmcn.12268","article-title":"Prevalence of cerebral palsy, co-occurring autism spectrum disorders, and motor functioning - Autism and Developmental Disabilities Monitoring Network, USA, 2008","volume":"56","author":"Christensen","year":"2014","journal-title":"Dev Med Child Neurol"},{"key":"R20-20260511","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1093\/brain\/123.10.2160","article-title":"Worster-Drought syndrome, a mild tetraplegic perisylvian cerebral palsy","volume":"123","author":"Clark","year":"2000","journal-title":"Brain"},{"key":"R21-20260511","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1126\/science.286.5442.1162","article-title":"Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks","volume":"286","author":"Cortez","year":"1999","journal-title":"Science"},{"key":"R22-20260511","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1038\/pr.2013.235","article-title":"Apolipoprotein E genotype and outcome in infants with hypoxic-ischemic encephalopathy","volume":"75","author":"Cotten","year":"2014","journal-title":"Pediatr Res"},{"key":"R23-20260511","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.jpeds.2013.06.062","article-title":"Maternal diagnosis of obesity and risk of cerebral palsy in the child","volume":"163","author":"Crisham Janik","year":"2013","journal-title":"J Pediatr"},{"key":"R24-20260511","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.earlhumdev.2004.04.009","article-title":"Inflammatory brain damage in preterm newborns--dry numbers, wet lab, and causal inferences","volume":"79","author":"Dammann","year":"2004","journal-title":"Early Hum Dev"},{"key":"R25-20260511","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s11017-016-9360-1","article-title":"Causality, mosaics, and the health sciences","volume":"37","author":"Dammann","year":"2016","journal-title":"Theor Med Bioeth"},{"key":"R26-20260511","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.pjnns.2017.06.012","article-title":"Missense mutation in the ITPR1 gene presenting with ataxic cerebral palsy: Description of an affected family and literature review","volume":"51","author":"Das","year":"2017","journal-title":"Neurol Neurochir Pol"},{"key":"R27-20260511","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/dmcn.13436","article-title":"Prevalence and characteristics of autism spectrum disorders in children with cerebral palsy","volume":"59","author":"Delobel-Ayoub","year":"2017","journal-title":"Dev Med Child Neurol"},{"key":"R28-20260511","doi-asserted-by":"crossref","first-page":"136108","DOI":"10.1016\/j.neulet.2021.136108","article-title":"Genetic, clinical and neuroimaging profiles of sporadic and autosomal recessive hereditary spastic paraplegia cases in Chinese","volume":"761","author":"Dong","year":"2021","journal-title":"Neurosci Lett"},{"key":"R29-20260511","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.nbd.2011.12.003","article-title":"NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex","volume":"45","author":"El Ghazi","year":"2012","journal-title":"Neurobiol Dis"},{"key":"R30-20260511","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1017\/S0012162206001162","article-title":"The Manual Ability Classification System (MACS) for children with cerebral palsy: scale development and evidence of validity and reliability","volume":"48","author":"Eliasson","year":"2006","journal-title":"Dev Med Child Neurol"},{"key":"R31-20260511","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1007\/s00415-019-09633-1","article-title":"Genotype-phenotype associations in hereditary spastic paraplegia: a systematic review and meta-analysis on 13,570 patients","volume":"268","author":"Erfanian Omidvar","year":"2021","journal-title":"J Neurol"},{"key":"R32-20260511","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.4103\/1673-5374.339001","article-title":"A three-dimensional matrix system containing melatonin and neural stem cells repairs damage from traumatic brain injury in rats","volume":"17","author":"Fang","year":"2022","journal-title":"Neural Regen Res"},{"key":"R33-20260511","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1469-8749.2011.04091.x","article-title":"Informing evidence-based clinical practice guidelines for children with cerebral palsy at risk of osteoporosis: a systematic review","volume":"54","author":"Fehlings","year":"2012","journal-title":"Dev Med Child Neurol"},{"key":"R34-20260511","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/s41436-020-01027-3","article-title":"An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids","volume":"23","author":"Ferdinandusse","year":"2021","journal-title":"Genet Med"},{"key":"R35-20260511","doi-asserted-by":"crossref","first-page":"e20160874","DOI":"10.1542\/peds.2016-0874","article-title":"Maternal prepregnancy BMI and risk of cerebral palsy in offspring","volume":"138","author":"Forthun","year":"2016","journal-title":"Pediatrics"},{"key":"R36-20260511","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/s41418-017-0012-4","article-title":"Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018","volume":"25","author":"Galluzzi","year":"2018","journal-title":"Cell Death Differ"},{"key":"R37-20260511","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ejpn.2007.07.001","article-title":"Cerebral palsy and congenital malformations","volume":"12","author":"Garne","year":"2008","journal-title":"Eur J Paediatr Neurol"},{"key":"R38-20260511","doi-asserted-by":"crossref","first-page":"e2996","DOI":"10.1371\/journal.pntd.0002996","article-title":"Neurocognitive outcome of children exposed to perinatal mother-to-child Chikungunya virus infection: the CHIMERE cohort study on Reunion Island","volume":"8","author":"G\u00e9rardin","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"R39-20260511","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1442-200x.2004.01886.x","article-title":"Significance of hypocarbia in the development of periventricular leukomalacia in preterm infants","volume":"46","author":"Giannakopoulou","year":"2004","journal-title":"Pediatr Int"},{"key":"R40-20260511","first-page":"1437","article-title":"Associations between inherited thrombophilias, gestational age, and cerebral palsy","volume":"193","author":"Gibson","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"R41-20260511","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1097\/01.AOG.0000252712.62241.1a","article-title":"Genetic polymorphisms and spontaneous preterm birth","volume":"109","author":"Gibson","year":"2007","journal-title":"Obstet Gynecol"},{"key":"R42-20260511","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1007\/s12031-019-01301-3","article-title":"A compound heterozygote for GCH1 mutation represents a case of atypical dopa-responsive dystonia","volume":"68","author":"Giri","year":"2019","journal-title":"J Mol Neurosci"},{"key":"R43-20260511","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1177\/0883073819854595","article-title":"congenital anomalies in children with cerebral palsy: a systematic review","volume":"34","author":"Goldsmith","year":"2019","journal-title":"J Child Neurol"},{"key":"R44-20260511","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1001\/jamapediatrics.2023.0008","article-title":"Diagnostic yield of exome sequencing in cerebral palsy and implications for genetic testing guidelines: a systematic review and meta-analysis","volume":"177","author":"Gonzalez-Mantilla","year":"2023","journal-title":"JAMA Pediatr"},{"key":"R45-20260511","doi-asserted-by":"crossref","first-page":"361","DOI":"10.24953\/turkjped.2018.04.002","article-title":"Apolipoprotein E allelic variants and cerebral palsy","volume":"60","author":"G\u00fcm\u00fc\u015f","year":"2018","journal-title":"Turk J Pediatr"},{"key":"R46-20260511","doi-asserted-by":"crossref","first-page":"242","DOI":"10.5606\/tftrd.2021.5481","article-title":"Are COL4A1 and COL4A2 gene polymorphisms associated with cerebral palsy?","volume":"67","author":"G\u00fcvener","year":"2021","journal-title":"Turk J Phys Med Rehabil"},{"key":"R47-20260511","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1469-8749.2011.04135.x","article-title":"Atypical timing and presentation of periventricular haemorrhagic infarction in preterm infants: the role of thrombophilia","volume":"54","author":"Harteman","year":"2012","journal-title":"Dev Med Child Neurol"},{"key":"R48-20260511","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1111\/j.1469-8749.2011.03996.x","article-title":"Developing and validating the Communication Function Classification System for individuals with cerebral palsy","volume":"53","author":"Hidecker","year":"2011","journal-title":"Dev Med Child Neurol"},{"key":"R49-20260511","doi-asserted-by":"crossref","first-page":"617740","DOI":"10.3389\/fneur.2020.617740","article-title":"Neuroimaging patterns and function in cerebral palsy-application of an MRI classification","volume":"11","author":"Himmelmann","year":"2020","journal-title":"Front Neurol"},{"key":"R50-20260511","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1053\/j.semperi.2008.09.011","article-title":"Maternal and infant thyroid disorders and cerebral palsy","volume":"32","author":"Hong","year":"2008","journal-title":"Semin Perinatol"},{"key":"R51-20260511","doi-asserted-by":"crossref","first-page":"6653","DOI":"10.1007\/s12035-015-9566-7","article-title":"TNF-\u03b1 and MTHFR polymorphisms associated with cerebral palsy in Chinese infants","volume":"53","author":"Hou","year":"2016","journal-title":"Mol Neurobiol"},{"key":"R52-20260511","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.cell.2016.12.044","article-title":"ApoE2, ApoE3, and ApoE4 differentially stimulate APP transcription and A\u03b2 secretion","volume":"168","author":"Huang","year":"2017","journal-title":"Cell"},{"key":"R53-20260511","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1038\/s41588-020-0695-1","article-title":"Mutations disrupting neuritogenesis genes confer risk for cerebral palsy","volume":"52","author":"Jin","year":"2020","journal-title":"Nat Genet"},{"key":"R54-20260511","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.ridd.2010.12.042","article-title":"Prevalence and functioning of children with cerebral palsy in four areas of the United States in 2006: a report from the Autism and Developmental Disabilities Monitoring Network","volume":"32","author":"Kirby","year":"2011","journal-title":"Res Dev Disabil"},{"key":"R55-20260511","doi-asserted-by":"crossref","first-page":"64","DOI":"10.2478\/v10039-011-0006-2","article-title":"Schizencephaly as a cause of spastic cerebral palsy","volume":"56","author":"Ku\u0142ak","year":"2011","journal-title":"Adv Med Sci"},{"key":"R56-20260511","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1542\/peds.2006-1083","article-title":"Association of apolipoprotein E genotype and cerebral palsy in children","volume":"119","author":"Kuroda","year":"2007","journal-title":"Pediatrics"},{"key":"R57-20260511","doi-asserted-by":"crossref","first-page":"4447","DOI":"10.3390\/ijms21124447","article-title":"Novel dominant KCNQ2 exon 7 partial in-frame duplication in a complex epileptic and neurodevelopmental delay syndrome","volume":"21","author":"Lazo","year":"2020","journal-title":"Int J Mol Sci"},{"key":"R58-20260511","doi-asserted-by":"crossref","first-page":"10440","DOI":"10.3390\/ijms241310440","article-title":"APOE locus-associated mitochondrial function and its implication in Alzheimer's disease and aging","volume":"24","author":"Lee","year":"2023","journal-title":"Int J Mol Sci"},{"key":"R59-20260511","doi-asserted-by":"crossref","first-page":"1201080","DOI":"10.3389\/fped.2023.1201080","article-title":"CTNNB1-related neurodevelopmental disorder mimics cerebral palsy: case report","volume":"11","author":"Lee","year":"2023","journal-title":"Front Pediatr"},{"key":"R60-20260511","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.3346\/jkms.2011.26.9.1244","article-title":"Dopa-responsive dystonia with a novel initiation codon mutation in the GCH1 gene misdiagnosed as cerebral palsy","volume":"26","author":"Lee","year":"2011","journal-title":"J Korean Med Sci"},{"key":"R61-20260511","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1203\/PDR.0b013e3181bf5fab","article-title":"Microbiologic and histologic characteristics of the extremely preterm infant's placenta predict white matter damage and later cerebral palsy","volume":"67","author":"Leviton","year":"2010","journal-title":"Pediatr Res"},{"key":"R62-20260511","doi-asserted-by":"crossref","first-page":"e602","DOI":"10.1212\/NXG.0000000000000602","article-title":"Mutation in ZDHHC15 leads to hypotonic cerebral palsy, autism, epilepsy, and intellectual disability","volume":"7","author":"Lewis","year":"2021","journal-title":"Neurol Genet"},{"key":"R63-20260511","doi-asserted-by":"crossref","first-page":"5008","DOI":"10.1038\/s41467-018-07416-2","article-title":"MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size","volume":"9","author":"Lewis","year":"2018","journal-title":"Nat Commun"},{"key":"R64-20260511","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.4103\/1673-5374.233455","article-title":"Acupuncture for cerebral palsy: A meta-analysis of randomized controlled trials","volume":"13","author":"Li","year":"2018","journal-title":"Neural Regen Res"},{"key":"R65-20260511","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/brain\/awab209","article-title":"In-depth analysis reveals complex molecular aetiology in a cohort of idiopathic cerebral palsy","volume":"145","author":"Li","year":"2022","journal-title":"Brain"},{"key":"R66-20260511","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1111\/apa.12983","article-title":"Genes determining the severity of cerebral palsy: the role of single nucleotide polymorphisms on the amount and structure of apolipoprotein E","volume":"104","author":"Lien","year":"2015","journal-title":"Acta Paediatr"},{"key":"R67-20260511","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.bbamcr.2007.04.009","article-title":"MUC1 inhibits cell proliferation by a beta-catenin-dependent mechanism","author":"Lillehoj","year":"2007","journal-title":"Biochim Biophys Acta"},{"key":"R68-20260511","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/dmcn.12972","article-title":"Prognostic factors for cerebral palsy and motor impairment in children born very preterm or very low birthweight: a systematic review","volume":"58","author":"Linsell","year":"2016","journal-title":"Dev Med Child Neurol"},{"key":"R69-20260511","first-page":"293","article-title":"On the influence of abnormal parturition, difficult labours, premature birth and asphyxia neonatorum on the mental and physical condition of the child, especially in relation to deformities","volume":"3","author":"Little","year":"1861","journal-title":"Trans Obstet Soc Lond"},{"key":"R70-20260511","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/00003086-196600460-00002","article-title":"On the influence of abnormal parturition, difficult labours, premature birth, and asphyxia neonatorum, on the mental and physical condition of the child, especially in relation to deformities","volume":"46","author":"Little","year":"1966","journal-title":"Clin Orthop Relat Res"},{"key":"R71-20260511","first-page":"737","article-title":"Apolipoprotein E knockout induced inflammatory responses related to microglia in neonatal mice brain via astrocytes","volume":"8","author":"Liu","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"R72-20260511","doi-asserted-by":"crossref","first-page":"166766","DOI":"10.1016\/j.bbadis.2023.166766","article-title":"Functional and structural impact of 10 ACADM missense mutations on human medium chain acyl-Coa dehydrogenase","volume":"1869","author":"Madeira","year":"2023","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"R73-20260511","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/EDE.0b013e31823a4205","article-title":"Children with cerebral palsy: racial disparities in functional limitations","volume":"23","author":"Maenner","year":"2012","journal-title":"Epidemiology"},{"key":"R74-20260511","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.annepidem.2016.01.001","article-title":"Prevalence of cerebral palsy and intellectual disability among children identified in two U.S. National Surveys, 2011-2013","volume":"26","author":"Maenner","year":"2016","journal-title":"Ann Epidemiol"},{"key":"R75-20260511","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1007\/s10072-019-03964-7","article-title":"GNAO1 mutation presenting as dyskinetic cerebral palsy","volume":"40","author":"Malaquias","year":"2019","journal-title":"Neurol Sci"},{"key":"R76-20260511","doi-asserted-by":"crossref","first-page":"2940","DOI":"10.3389\/fimmu.2019.02940","article-title":"Ataxia telangiectasia diagnosed on newborn screening-case cohort of 5 years' experience","volume":"10","author":"Mandola","year":"2019","journal-title":"Front Immunol"},{"key":"R77-20260511","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1002\/cpt.1927","article-title":"Exome sequencing reveals common and rare variants in F5 associated with ACE inhibitor and angiotensin receptor blocker-induced angioedema","volume":"108","author":"Maroteau","year":"2020","journal-title":"Clin Pharmacol Ther"},{"key":"R78-20260511","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/s41419-018-0815-3","article-title":"Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis","volume":"9","author":"Maruyama","year":"2018","journal-title":"Cell Death Dis"},{"key":"R79-20260511","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1111\/dmcn.15346","article-title":"Global prevalence of cerebral palsy: A systematic analysis","volume":"64","author":"McIntyre","year":"2022","journal-title":"Dev Med Child Neurol"},{"key":"R80-20260511","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1111\/dmcn.12957","article-title":"Language outcomes of children with cerebral palsy aged 5 years and 6 years: a population-based study","volume":"58","author":"Mei","year":"2016","journal-title":"Dev Med Child Neurol"},{"key":"R81-20260511","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1093\/cid\/cix166","article-title":"Lessons learned at the epicenter of Brazil's congenital zika epidemic: evidence from 87 confirmed cases","volume":"64","author":"Meneses","year":"2017","journal-title":"Clin Infect Dis"},{"key":"R82-20260511","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.yapd.2019.04.002","article-title":"Cerebral palsy: diagnosis, epidemiology, genetics, and clinical update","volume":"66","author":"Michael-Asalu","year":"2019","journal-title":"Adv Pediatr"},{"key":"R83-20260511","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/ppe.12082","article-title":"Maternal infections during pregnancy and cerebral palsy: a population-based cohort study","volume":"27","author":"Miller","year":"2013","journal-title":"Paediatr Perinat Epidemiol"},{"key":"R84-20260511","doi-asserted-by":"crossref","first-page":"e2030","DOI":"10.1002\/pri.2030","article-title":"Sensory integration versus Masgutova neuro-sensorimotor reflex integration program on controlling primitive reflexes and gross motor abilities in children with diplegic cerebral palsy","author":"Mohamed","year":"2023","journal-title":"Physiother Res Int"},{"key":"R85-20260511","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s13148-018-0457-4","article-title":"Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation","volume":"10","author":"Mohandas","year":"2018","journal-title":"Clin Epigenetics"},{"key":"R86-20260511","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1001\/jama.2020.26148","article-title":"Molecular diagnostic yield of exome sequencing in patients with cerebral palsy","volume":"325","author":"Moreno-De-Luca","year":"2021","journal-title":"JAMA"},{"key":"R87-20260511","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/j.1469-8749.1992.tb11479.x","article-title":"Cerebral palsy epidemiology: where are we now and where are we going?","volume":"34","author":"Mutch","year":"1992","journal-title":"Dev Med Child Neurol"},{"key":"R88-20260511","doi-asserted-by":"crossref","first-page":"583.e581","DOI":"10.1016\/j.ajog.2022.11.1277","article-title":"Fetal heart rate evolution and brain imaging findings in preterm infants with severe cerebral palsy","volume":"228","author":"Nakao","year":"2023","journal-title":"Am J Obstet Gynecol"},{"key":"R89-20260511","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1056\/NEJM198607103150202","article-title":"Antecedents of cerebral palsy","volume":"315","author":"Nelson","year":"1986","journal-title":"N Engl J Med"},{"key":"R90-20260511","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1002\/ana.410440413","article-title":"Neonatal cytokines and coagulation factors in children with cerebral palsy","volume":"44","author":"Nelson","year":"1998","journal-title":"Ann Neurol"},{"key":"R91-20260511","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/pr.2013.117","article-title":"Single-nucleotide polymorphism associations with preterm delivery: a case-control replication study and meta-analysis","volume":"74","author":"O'Callaghan","year":"2013","journal-title":"Pediatr Res"},{"key":"R92-20260511","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.nrl.2021.01.006","article-title":"Epidemiology of ataxia and hereditary spastic paraplegia in Spain: A cross-sectional study","volume":"38","author":"Ortega Suero","year":"2023","journal-title":"Neurologia (Engl Ed)"},{"key":"R93-20260511","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/dmcn.12808","article-title":"Variation in cerebral palsy profile by socio-economic status","volume":"58","author":"Oskoui","year":"2016","journal-title":"Dev Med Child Neurol"},{"key":"R95-20260511","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/j.1469-8749.1997.tb07414.x","article-title":"Development and reliability of a system to classify gross motor function in children with cerebral palsy","volume":"39","author":"Palisano","year":"1997","journal-title":"Dev Med Child Neurol"},{"key":"R96-20260511","doi-asserted-by":"crossref","first-page":"Np196","DOI":"10.1177\/0883073813510971","article-title":"Is prepregnancy obesity associated with risk of cerebral palsy and epilepsy in children?","volume":"29","author":"Pan","year":"2014","journal-title":"J Child Neurol"},{"key":"R97-20260511","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1093\/brain\/awv117","article-title":"De novo point mutations in patients diagnosed with ataxic cerebral palsy","volume":"138","author":"Parolin Schnekenberg","year":"2015","journal-title":"Brain"},{"key":"R98-20260511","first-page":"30","article-title":"Overview of four functional classification systems commonly used in cerebral palsy","volume":"4","author":"Paulson","year":"2017","journal-title":"Children (Basel)"},{"key":"R99-20260511","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1001\/jama.1952.02930180032007","article-title":"Infantile cerebral palsy; classification and clinical correlations","volume":"149","author":"Perlstein","year":"1952","journal-title":"J Am Med Assoc"},{"key":"R100-20260511","doi-asserted-by":"crossref","first-page":"S167","DOI":"10.1542\/peds.2017-2038F","article-title":"Motor abnormalities and epilepsy in infants and children with evidence of congenital Zika virus infection","volume":"141","author":"Pessoa","year":"2018","journal-title":"Pediatrics"},{"key":"R101-20260511","doi-asserted-by":"crossref","first-page":"e0264177","DOI":"10.1371\/journal.pone.0264177","article-title":"The natural history of ataxia-telangiectasia (A-T): A systematic review","volume":"17","author":"Petley","year":"2022","journal-title":"PLoS One"},{"key":"R102-20260511","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/dmcn.12228","article-title":"Population-based studies of brain imaging patterns in cerebral palsy","volume":"56","author":"Reid","year":"2014","journal-title":"Dev Med Child Neurol"},{"key":"R103-20260511","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1111\/dmcn.12800","article-title":"Grey matter injury patterns in cerebral palsy: associations between structural involvement on MRI and clinical outcomes","volume":"57","author":"Reid","year":"2015","journal-title":"Dev Med Child Neurol"},{"key":"R104-20260511","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/dmcn.13001","article-title":"Temporal trends in cerebral palsy by impairment severity and birth gestation","volume":"2","author":"Reid","year":"2016","journal-title":"Dev Med Child Neurol 58 Suppl"},{"key":"R105-20260511","first-page":"233","article-title":"Etiology of congenital cerebral palsy","volume":"79","author":"Roboz","year":"1962","journal-title":"Arch Pediatr (N Y)"},{"key":"R106-20260511","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.semcdb.2018.09.012","article-title":"Tenascins in CNS lesions","volume":"89","author":"Roll","year":"2019","journal-title":"Semin Cell Dev Biol"},{"key":"R107-20260511","first-page":"8","article-title":"A report: the definition and classification of cerebral palsy April 2006","volume":"109","author":"Rosenbaum","year":"2007","journal-title":"Dev Med Child Neurol Suppl"},{"key":"R108-20260511","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1469-8749.2008.02045.x","article-title":"Development of the Gross Motor Function Classification System for cerebral palsy","volume":"50","author":"Rosenbaum","year":"2008","journal-title":"Dev Med Child Neurol"},{"key":"R109-20260511","first-page":"632","article-title":"Incidence of infantile cerebral palsy","volume":"46","author":"Sandifer","year":"1953","journal-title":"Proc R Soc Med"},{"key":"R110-20260511","first-page":"133","article-title":"Diagnostic work-up and rehabilitation of cerebral visual impairment in infancy: A case of epileptic perinatal encephalopathy due to KCNQ2-related channelopathy","volume":"11","author":"Saviola","year":"2018","journal-title":"J Pediatr Rehabil Med"},{"key":"R111-20260511","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/jimd.12463","article-title":"Novel imaging findings in pyruvate dehydrogenase complex (PDHc) deficiency-Results from a nationwide population-based study","volume":"45","author":"Savvidou","year":"2022","journal-title":"J Inherit Metab Dis"},{"key":"R112-20260511","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.parkreldis.2018.11.019","article-title":"Phenomenology and clinical course of movement disorder in GNAO1 variants: Results from an analytical review","volume":"61","author":"Schirinzi","year":"2019","journal-title":"Parkinsonism Relat Disord"},{"key":"R113-20260511","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/dmcn.12352","article-title":"Development and reliability of a system to classify the eating and drinking ability of people with cerebral palsy","volume":"56","author":"Sellers","year":"2014","journal-title":"Dev Med Child Neurol"},{"key":"R114-20260511","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1212\/WNL.0000000000207265","article-title":"Child neurology: cortical malformations in preterm infants: case from a prospective cohort","volume":"101","author":"Selvanathan","year":"2023","journal-title":"Neurology"},{"key":"R115-20260511","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.pediatrneurol.2020.02.002","article-title":"Congenital malformations in children with cerebral palsy: is prematurity protective?","volume":"108","author":"S\u00e9v\u00e8re","year":"2020","journal-title":"Pediatr Neurol"},{"key":"R116-20260511","doi-asserted-by":"crossref","first-page":"114","DOI":"10.4103\/ijabmr.IJABMR_355_20","article-title":"Mitochondrial fission factor gene mutation: a dilemma for prenatal diagnosis","volume":"11","author":"Sharma","year":"2021","journal-title":"Int J Appl Basic Med Res"},{"key":"R117-20260511","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1021\/ar800201v","article-title":"Design of selective neuronal nitric oxide synthase inhibitors for the prevention and treatment of neurodegenerative diseases","volume":"42","author":"Silverman","year":"2009","journal-title":"Acc Chem Res"},{"key":"R118-20260511","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1002\/dneu.22546","article-title":"The role of mitochondria in axon development and regeneration","volume":"78","author":"Smith","year":"2018","journal-title":"Dev Neurobiol"},{"key":"R119-20260511","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1111\/dmcn.12467","article-title":"Congenital cytomegalovirus is associated with severe forms of cerebral palsy and female sex in a retrospective population-based study","volume":"56","author":"Smithers-Sheedy","year":"2014","journal-title":"Dev Med Child Neurol"},{"key":"R120-20260511","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/dmcn.12262","article-title":"What constitutes cerebral palsy in the twenty-first century?","volume":"56","author":"Smithers-Sheedy","year":"2014","journal-title":"Dev Med Child Neurol"},{"key":"R121-20260511","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.jpeds.2016.10.024","article-title":"Congenital cytomegalovirus among children with cerebral palsy","volume":"181","author":"Smithers-Sheedy","year":"2017","journal-title":"J Pediatr"},{"key":"R122-20260511","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1111\/dmcn.12456","article-title":"Contribution of socio-economic status on the prevalence of cerebral palsy: a systematic search and review","volume":"56","author":"Solaski","year":"2014","journal-title":"Dev Med Child Neurol"},{"key":"R123-20260511","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1001\/jamaneurol.2022.3549","article-title":"Molecular diagnostic yield of exome sequencing and chromosomal microarray in cerebral palsy: a systematic review and meta-analysis","volume":"79","author":"Srivastava","year":"2022","journal-title":"JAMA Neurol"},{"key":"R124-20260511","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.ejpn.2014.12.017","article-title":"Child apolipoprotein E gene variants and risk of cerebral palsy: estimation from case-parent triads","volume":"19","author":"Stoknes","year":"2015","journal-title":"Eur J Paediatr Neurol"},{"key":"R125-20260511","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1001\/jamapsychiatry.2020.0306","article-title":"Association of preeclampsia in term births with neurodevelopmental disorders in offspring","volume":"77","author":"Sun","year":"2020","journal-title":"JAMA Psychiatry"},{"key":"R126-20260511","doi-asserted-by":"crossref","first-page":"102303","DOI":"10.1016\/j.scr.2021.102303","article-title":"Generation of GPAM knockout human embryonic stem cell line SYSUe-008-A using CRISPR\/Cas9","volume":"53","author":"Sun","year":"2021","journal-title":"Stem Cell Res"},{"key":"R127-20260511","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/s10038-018-0432-0","article-title":"A case of new PCDH12 gene variants presented as dyskinetic cerebral palsy with epilepsy","volume":"63","author":"Suzuki-Muromoto","year":"2018","journal-title":"J Hum Genet"},{"key":"R128-20260511","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1002\/acn3.551","article-title":"Genomic analysis identifies masqueraders of full-term cerebral palsy","volume":"5","author":"Takezawa","year":"2018","journal-title":"Ann Clin Transl Neurol"},{"key":"R129-20260511","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1002\/ana.410420316","article-title":"Factor V Leiden mutation: an unrecognized cause of hemiplegic cerebral palsy, neonatal stroke, and placental thrombosis","volume":"42","author":"Thorarensen","year":"1997","journal-title":"Ann Neurol"},{"key":"R130-20260511","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.3390\/cells10071678","article-title":"Current knowledge of endolysosomal and autophagy defects in hereditary spastic paraplegia","volume":"10","author":"Toupenet Marchesi","year":"2021","journal-title":"Cells"},{"key":"R131-20260511","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1093\/brain\/awac439","article-title":"Metabolic patterns in brain 18F-fluorodeoxyglucose PET relate to aetiology in paediatric dystonia","volume":"146","author":"Tsagkaris","year":"2023","journal-title":"Brain"},{"key":"R132-20260511","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/j.ridd.2014.03.048","article-title":"Association between mechanical ventilation and neurodevelopmental disorders in a nationwide cohort of extremely low birth weight infants","volume":"35","author":"Tsai","year":"2014","journal-title":"Res Dev Disabil"},{"key":"R133-20260511","doi-asserted-by":"crossref","first-page":"e0191724","DOI":"10.1371\/journal.pone.0191724","article-title":"Association between socioeconomic status and cerebral palsy","volume":"13","author":"Tseng","year":"2018","journal-title":"PLoS One"},{"key":"R134-20260511","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1046\/j.1440-1789.1999.00197.x","article-title":"Neuronal migration disorders in cerebral palsy","volume":"19","author":"Tsutsui","year":"1999","journal-title":"Neuropathology"},{"key":"R135-20260511","first-page":"279","article-title":"The role of prothrombotic factors in children with hemiplegic cerebral palsy","volume":"67","author":"T\u00fcredi Yildirim","year":"2015","journal-title":"Minerva Pediatr"},{"key":"R136-20260511","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1177\/0883073817751303","article-title":"Are extremely low gestational age newborns born to obese women at increased risk of cerebral palsy at 2 years?","volume":"33","author":"van der Burg","year":"2018","journal-title":"J Child Neurol"},{"key":"R137-20260511","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.pediatrneurol.2020.02.007","article-title":"Neonatal brain microstructure and machine-learning-based prediction of early language development in children born very preterm","volume":"108","author":"Vassar","year":"2020","journal-title":"Pediatr Neurol"},{"key":"R138-20260511","doi-asserted-by":"crossref","first-page":"113643","DOI":"10.1016\/j.expneurol.2021.113643","article-title":"A systematic review of neurogenesis in animal models of early brain damage: Implications for cerebral palsy","volume":"340","author":"Visco","year":"2021","journal-title":"Exp Neurol"},{"key":"R139-20260511","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1111\/dmcn.14964","article-title":"Reduced mitochondrial DNA and OXPHOS protein content in skeletal muscle of children with cerebral palsy","volume":"63","author":"von Walden","year":"2021","journal-title":"Dev Med Child Neurol"},{"key":"R140-20260511","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1038\/s41436-020-0768-7","article-title":"Loss of TNR causes a nonprogressive neurodevelopmental disorder with spasticity and transient opisthotonus","volume":"22","author":"Wagner","year":"2020","journal-title":"Genet Med"},{"key":"R141-20260511","doi-asserted-by":"crossref","first-page":"20344","DOI":"10.1073\/pnas.0703664105","article-title":"The tumor suppressor Fhit acts as a repressor of beta-catenin transcriptional activity","volume":"104","author":"Weiske","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R142-20260511","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1002\/mds.29323","article-title":"Spectrum of FAR1 (fatty acyl-CoA reductase 1) variants and related neurological conditions","volume":"38","author":"Westenberger","year":"2023","journal-title":"Mov Disord"},{"key":"R143-20260511","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s10654-017-0319-y","article-title":"Paediatric population neuroimaging and the Generation R Study: the second wave","volume":"33","author":"White","year":"2018","journal-title":"Eur J Epidemiol"},{"key":"R144-20260511","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1001\/jama.284.11.1417","article-title":"Chorioamnionitis as a risk factor for cerebral palsy: A meta-analysis","volume":"284","author":"Wu","year":"2000","journal-title":"Jama"},{"key":"R145-20260511","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1203\/PDR.0b013e31823240dd","article-title":"Candidate genes and risk for CP: a population-based study","volume":"70","author":"Wu","year":"2011","journal-title":"Pediatr Res"},{"key":"R146-20260511","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.4103\/1673-5374.357906","article-title":"Neuronal nitric oxide synthase\/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy","volume":"18","author":"Xu","year":"2023","journal-title":"Neural Regen Res"},{"key":"R147-20260511","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1093\/hmg\/ddt582","article-title":"Sex- and age-interacting eQTLs in human complex diseases","volume":"23","author":"Yao","year":"2014","journal-title":"Hum Mol Genet"},{"key":"R148-20260511","first-page":"808","article-title":"Thrombophilia: a risk factor for cerebral palsy?","volume":"7","author":"Yehezkely-Schildkraut","year":"2005","journal-title":"Isr Med Assoc J"},{"key":"R149-20260511","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/S1474-4422(20)30312-4","article-title":"Monogenic variants in dystonia: an exome-wide sequencing study","volume":"19","author":"Zech","year":"2020","journal-title":"Lancet Neurol"},{"key":"R150-20260511","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.ando.2016.02.006","article-title":"SFE\/SFHTA\/AFCE consensus on primary aldosteronism, part 5: Genetic diagnosis of primary aldosteronism","volume":"77","author":"Zennaro","year":"2016","journal-title":"Ann Endocrinol (Paris)"},{"key":"R151-20260511","doi-asserted-by":"crossref","first-page":"704","DOI":"10.3389\/fneur.2020.00704","article-title":"Birth asphyxia is associated with increased risk of cerebral palsy: a meta-analysis","volume":"11","author":"Zhang","year":"2020","journal-title":"Front Neurol"},{"key":"R152-20260511","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12920-018-0394-2","article-title":"Comprehensive off-target analysis of dCas9-SAM-mediated HIV reactivation via long noncoding RNA and mRNA profiling","volume":"11","author":"Zhang","year":"2018","journal-title":"BMC Med Genomics"},{"key":"R153-20260511","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.4103\/1673-5374.360245","article-title":"Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase\/endothelial nitric oxide synthase pathway","volume":"18","author":"Zhao","year":"2023","journal-title":"Neural Regen Res"},{"key":"R154-20260511","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.ejpn.2019.02.001","article-title":"The genetic etiology in cerebral palsy mimics: The results from a Greek tertiary care center","volume":"23","author":"Zouvelou","year":"2019","journal-title":"Eur J Paediatr Neurol"}],"container-title":["Neural Regeneration Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/1673-5374.385855","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:15:50Z","timestamp":1787166950000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/1673-5374.385855"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,22]]},"references-count":153,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/1673-5374.385855","relation":{},"ISSN":["1673-5374","1876-7958"],"issn-type":[{"value":"1673-5374","type":"print"},{"value":"1876-7958","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,22]]},"assertion":[{"value":"2023-04-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}