{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:22:47Z","timestamp":1787840567187,"version":"build-2784847793"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Musculoskeletal manifestations (MSM) of inflammatory bowel diseases (IBDs) are usually the most frequent extraintestinal manifestations. However, they are not paid enough attention during regular office visits. This cross-sectional study aimed to draw a clinical picture of MSM and their relationships with other findings in patients with IBD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Patients of our IBD cohort between March 2012 and September 2013 were consecutively evaluated. Those with current or past history of any MSM were examined by a rheumatologist. The outcome of interest was different MSMs. Distribution of IBD manifestations between the two groups of patients with (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 20) and without (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 253) MSM was compared. Logistic regression analysis was employed to find the relationships of demographic, clinical, and laboratory findings with MSM.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Two hundred and seventy-three patients were enrolled. Forty-two patients (15.4%) had extraintestinal manifestations of which twenty patients (7.5%) had at least one MSM. 7\/20 patients (35%) versus 22\/253 (8.7%) had other extraintestinal manifestations (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0001). 12\/20 patients (57%) had arthritis (polyarthritis, 33% and oligoarthritis, 67%). The most frequent involved joints were knee and ankle observed in 8 (40%) and 7 (35%) patients, respectively. The inflammatory back pain was recorded in 5\/20 patients (25%) whereas two patients (10%) had ankylosing spondylitis. In regression analysis, oral aphthous (odds ratio [OR] =8.8 [95% confidence intervals (CI), 1.7\u201345],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.009) and other extraintestinal manifestations (OR = 5.2 [95% CI, 1.3\u201320],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.02) were significantly related with arthritis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The most frequent extraintestinal manifestations in patients with IBD were MSM. Knee and ankle were the most frequent involved joints. Extraintestinal manifestations were determinant variables of arthritis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/1735-1995.183989","type":"journal-article","created":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T05:01:03Z","timestamp":1465880463000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Relationship between articular and nonarticular manifestations in inflammatory bowel diseases"],"prefix":"10.4103","volume":"21","author":[{"given":"Alimohammad","family":"Fatemi","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hourossadat Hashemi","family":"Jazi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hasan","family":"Emami","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Poursina Hakim Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Kazemizadeh","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Poursina Hakim Research Institute, Islamic Azad University of Najafabad, Najafabad, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Tavakkoli","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Smiley","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Indiana University School of Public Health, Bloomington, IN, 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