{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T07:04:35Z","timestamp":1694243075688},"reference-count":29,"publisher":"Scientific Scholar","content-domain":{"domain":["cytojournal.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Objective:<\/jats:title>\n<jats:p>The objective of this study is to evaluate the cytological accuracy of endobronchial ultrasound-guided transbronchial fine-needle aspiration (EBUS-TFNA) of the mediastinal mass\/nodular lesions.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Study Design:<\/jats:title>\n<jats:p>Over 3\u00bd years from inception at King Khalid University Hospital, a retrospective analysis of the cytological diagnoses of all the EBUS-TFNA procedures performed in 80 patients who had mediastinal mass\/nodular enlargement. Cytology results were reviewed and correlated with the histologic follow-up.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Results:<\/jats:title>\n<jats:p>Of the 80 patients who underwent EBUS-TFNA, 15 cases (18.75%) were positive for malignancy, 48 cases (60%) negative for malignancy and 17 cases (21.25%) unsatisfactory. Of the 48 cases, which were negative for malignancy, 24 (50%) cases were of granulomatous inflammation. The overall diagnostic yield of our EBUS-TFNA specimen was 78.75%. Forty-seven cases (58.75%) of 80 cases had histological follow-up biopsies. Among them, 32 cases (68%) had the same cytological and histological diagnosis and 15 cases (31.09%) had discordance between the cytology and the follow-up histological diagnosis. The sensitivity, specificity, and positive and negative predictive values for diagnosing granulomas by EBUS-TFNA are 77%, 82%, 83%, and 75% and for diagnosing malignancy are 71%, 100%, 100%, and 82%, respectively.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>Preliminary results show that cytological samples obtained through EBUS-TFNA are accurate and specific in making a diagnosis of the mediastinal mass\/nodular lesions. Its optimum use depends on the effective collaboration between the cytotechnologist, pathologist, and the bronchoscopist.<\/jats:p>\n<\/jats:sec>","DOI":"10.4103\/1742-6413.137760","type":"journal-article","created":{"date-parts":[[2014,7,30]],"date-time":"2014-07-30T07:36:21Z","timestamp":1406705781000},"page":"19","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Utility and diagnostic accuracy of endobronchial ultrasound-guided transbronchial fine-needle aspiration cytology of mediastinal lesions: Saudi Arabian experience"],"prefix":"10.25259","volume":"11","author":[{"given":"Emad","family":"Raddaoui","sequence":"first","affiliation":[{"name":"Address: Department of Pathology, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esam H","family":"Alhamad","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaesta Naseem","family":"Zaidi","sequence":"additional","affiliation":[{"name":"Address: Department of Pathology, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatmah F","family":"Al-Habeeb","sequence":"additional","affiliation":[{"name":"Address: Department of Pathology, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maha","family":"Arafah","sequence":"additional","affiliation":[{"name":"Address: Department of Pathology, King Khalid University Hospital, College of Medicine, King 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