{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T13:23:33Z","timestamp":1725542613668},"reference-count":13,"publisher":"Scientific Scholar","content-domain":{"domain":["cytojournal.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Aims:<\/jats:title>\n<jats:p>To assess the adequacy of intraoperative scrape cytology during percutaneous vertebroplasty by correlating results with corresponding histopathology.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Settings and Design:<\/jats:title>\n<jats:p>Vertebroplasty is a procedure increasingly used to treat painful vertebral compression fractures. The history and presentation of osteoporotic fractures are straightforward, but difficulty arises in differentiating infective from neoplastic lesions, especially in cases where the magnetic resonance imaging is equivocal. The procedure involves injection of polymethyl methacrylate (bone cement) into the pathological vertebral body and gives dramatic pain relief. It is indicated in osteoporotic and neoplastic lesions but contraindicated in infections. Hence, intraoperative evaluation of a specimen is essential to aid in the decision of performing vertebroplasty.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Subjects and Methods:<\/jats:title>\n<jats:p>A total of 128 patients with vertebral lesions underwent core biopsy and scrape cytology from June 2006 to June 2015. Based on the findings of cytological examination, malignant lesions were subjected to vertebroplasty. In lesions with infective etiology, vertebroplasty was abandoned and antibiotic or antituberculous therapy started.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Results:<\/jats:title>\n<jats:p>The overall diagnostic accuracy of scrape cytology was excellent with 97.58% cases correlating with the final histopathological diagnosis. Specificity was 100%, positive predictive value was 100% and negative predictive value was 33.33%.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st5\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>Scrape cytology is a simple, rapid, accurate cytodiagnostic technique and should be routinely utilized in vertebral lesions for intraoperative consultation and decision making during vertebroplasty.<\/jats:p>\n<\/jats:sec>","DOI":"10.4103\/1742-6413.182954","type":"journal-article","created":{"date-parts":[[2016,5,25]],"date-time":"2016-05-25T03:01:42Z","timestamp":1464145302000},"page":"11","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The role of intraoperative scrape cytology in vertebroplasty"],"prefix":"10.25259","volume":"13","author":[{"given":"Renuka Venkata","family":"Inuganti","sequence":"first","affiliation":[{"name":"Address: Department of Pathology and Orthopedics, NRI Medical College, Guntur, Andhra Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rami Reddy","family":"Mettu","sequence":"additional","affiliation":[{"name":"Address: Department of Pathology and Orthopedics, NRI Medical College, Guntur, Andhra Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harsha Vardhan","family":"Surath","sequence":"additional","affiliation":[{"name":"Address: Department of Pathology and Orthopedics, NRI Medical College, Guntur, Andhra Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amarnath","family":"Surath","sequence":"additional","affiliation":[{"name":"Address: Department of Pathology and Orthopedics, NRI Medical College, Guntur, Andhra Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2016,5,25]]},"reference":[{"key":"10.4103\/1742-6413.182954\/ref-1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.4103\/0970-9371.86350","article-title":"Intraoperative scrape cytology: Adult granulosa cell tumor of ovary","volume":"28","author":"Deb","year":"2011","journal-title":"J Cytol"},{"key":"10.4103\/1742-6413.182954\/ref-2","first-page":"83","article-title":"Percutaneous vertebroplasty guided by a combination of CT and fluoroscopy","volume":"15","author":"Gangi","year":"1994","journal-title":"AJNR Am J Neuroradiol"},{"issue":"1 Suppl","key":"10.4103\/1742-6413.182954\/ref-3","first-page":"21","article-title":"Percutaneous vertebroplasty and kyphoplasty for painful vertebral body fractures in cancer patients","volume":"98","author":"Fourney","year":"2003","journal-title":"J Neurosurg"},{"key":"10.4103\/1742-6413.182954\/ref-4","doi-asserted-by":"crossref","first-page":"855","DOI":"10.4184\/asj.2015.9.6.855","article-title":"Percutaneous vertebroplasty: A new serial injection technique to minimize cement leak","volume":"9","author":"Elnoamany","year":"2015","journal-title":"Asian Spine J"},{"key":"10.4103\/1742-6413.182954\/ref-5","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1259\/bjr\/10254271","article-title":"Percutaneous vertebroplasty: Indications, contraindications, and technique","volume":"76","author":"Peh","year":"2003","journal-title":"Br J Radiol"},{"key":"10.4103\/1742-6413.182954\/ref-6","first-page":"477","article-title":"Role of scrape cytology in rapid intraoperative diagnosis. Value and limitations","volume":"28","author":"Shidham","year":"1984","journal-title":"Acta Cytol"},{"key":"10.4103\/1742-6413.182954\/ref-7","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/dc.10273","article-title":"Scrape cytology of the ovaries: Potential role in intraoperative consultation of ovarian lesions","volume":"28","author":"Khunamornpong","year":"2003","journal-title":"Diagn Cytopathol"},{"key":"10.4103\/1742-6413.182954\/ref-8","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1016\/j.spinee.2014.01.033","article-title":"Increasing the specimen adequacy of transpedicular vertebral body biopsies. 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