{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T03:30:44Z","timestamp":1777087844786,"version":"3.51.4"},"reference-count":45,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T00:00:00Z","timestamp":1663804800000},"content-version":"vor","delay-in-days":3127,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:p>The pathogenesis underlying communicating hydrocephalus has been centered on impaired cerebrospinal fluid (CSF) outflow secondary to abnormal CSF pulsation and venous hypertension. Hydrodynamic theory of hydrocephalus fares better than traditional theory in explaining the possible mechanisms underlying communicating hydrocephalus. Nonetheless, hydrodynamic theory alone could not fully explain some conditions that have ventriculomegaly but without hydrocephalus. By revisiting brain buoyancy from a fresher perspective, called microgravity environment of the brain, introducing wider concepts of anatomical and physiological compensatory-decompensatory phases for a persistent raise in intracranial pressure, and along with combining these two concepts with the previously well-accepted concepts of Monro-Kellie doctrine, intracranial hypertension, cerebral blood flow, cerebral perfusion pressure, brain compliance and elasticity, cerebral autoregulation, blood-brain and blood-CSF barriers, venous and cardiopulmonary hypertension, Windkessel phenomenon, and cerebral pulsation, we provide plausible explanations to the pathogenesis for communicating hydrocephalus and its related disorders.<\/jats:p>","DOI":"10.4103\/1793-5482.131058","type":"journal-article","created":{"date-parts":[[2014,4,19]],"date-time":"2014-04-19T07:13:11Z","timestamp":1397891591000},"page":"7-13","source":"Crossref","is-referenced-by-count":7,"title":["Microgravity environment and compensatory: Decompensatory phases for intracranial hypertension form new perspectives to explain mechanism underlying communicating hydrocephalus and its related disorders"],"prefix":"10.1055","volume":"9","author":[{"given":"Zamzuri","family":"Idris","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia 16150, Kubang Kerian, Kelantan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muzaimi","family":"Mustapha","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia 16150, Kubang Kerian, Kelantan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jafri","family":"Abdullah","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia 16150, Kubang Kerian, 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