{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T04:12:28Z","timestamp":1778731948005,"version":"3.51.4"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"vor","delay-in-days":1845,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>\n          Introduction: Debate continues as to the optimum treatment for craniopharyngioma; radical surgical resection or partial resection followed by radiotherapy. Radical surgical resection may be complicated by intraoperative injury to surrounding structures and stormy postoperative hormonal problem. This study aims to examine the result of safe maximal surgical resection. Materials and Methods: Retrospective study of all histopathologically proven craniopharyngiomas who had undergone surgical resection over an almost 8 year period was included. Data were collected reviewing demography, clinical presentation, hormonal dysfunction, extent of resection and visual deterioration. Outcome was measured in terms of Glasgow outcome scale and recurrence. Results: Of 25 patients, 68% were male, and 32% were female. Age of patients ranged from 7 to 58 years with a mean of 30.12 \u00b1 16.42 years. Patients presented with visual deterioration were 76% and with a headache were 68%. Mean duration of symptoms was 10.64 \u00b1 14.28 months. Gross total resection was done in 21 (84%), while subtotal resection in 4 (16%) who also received subsequent adjuvant radiotherapy. During the postoperative period, diabetes insipidus developed in 84% patients, but none had it permanently. Favorable outcome was found in 88% patients. However, there were 4% operative mortality with overall mortality of 8% and tumor recurrence in 8% patients. Conclusion: Gross total excision if judiciously decided intraoperatively has a favorable outcome with acceptable morbidity.<\/jats:p>","DOI":"10.4103\/1793-5482.150228","type":"journal-article","created":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T11:34:21Z","timestamp":1422444861000},"page":"514-518","source":"Crossref","is-referenced-by-count":10,"title":["Outcome following surgical resection of craniopharyngiomas: A case series"],"prefix":"10.1055","volume":"12","author":[{"given":"K","family":"Bidur","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Institute of Neurological and Allied sciences, Bansbari, Kathmandu"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devkota","family":"Prasad","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Institute of Neurological and Allied sciences, Bansbari, Kathmandu"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,9,20]]},"reference":[{"key":"key-10.4103\/1793-5482.150228-1","unstructured":"Samii M, Tatagiba M. Craniopharyngioma. In: Kaye AH, Laws ER Jr, editors. Brain Tumors: An Encyclopedic Approach. New York: Churchill Livingstone; 1995. p. 873-94."},{"key":"key-10.4103\/1793-5482.150228-2","first-page":"503","volume-title":"Epidemiology of central nervous system tumors in childhood and adolescence based on the new WHO classification","author":"Rickert","year":"2001","journal-title":"Childs Nerv Syst"},{"key":"key-10.4103\/1793-5482.150228-3","first-page":"17","volume-title":"Surgical treatment of craniopharyngiomas","author":"Samii","year":"1991","journal-title":"Zentralbl Neurochir"},{"key":"key-10.4103\/1793-5482.150228-4","first-page":"539","volume-title":"Radical excision of craniopharyngioma by the temporal route: A review of 50 patients","author":"Symon","year":"1991","journal-title":"Br J Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-5","first-page":"3","volume-title":"Total removal of craniopharyngiomas.Approaches and long-term results in 144 patients","author":"Yasargil","year":"1990","journal-title":"J Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-6","first-page":"371","volume-title":"Craniopharyngiomas","author":"Karavitaki","year":"2006","journal-title":"Endocr Rev"},{"key":"key-10.4103\/1793-5482.150228-7","first-page":"291","volume-title":"Long-term outcomes for surgically resected craniopharyngiomas","author":"Duff","year":"2000","journal-title":"Neurosurgery"},{"key":"key-10.4103\/1793-5482.150228-8","first-page":"237","volume-title":"Surgical treatment of craniopharyngiomas: Experience with 168 patients","author":"Fahlbusch","year":"1999","journal-title":"J Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-9","first-page":"534","volume-title":"Craniopharyngiomas in children.Long-term effects of conservative surgical procedures combined with radiation therapy","author":"Fischer","year":"1990","journal-title":"J Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-10","first-page":"7","volume-title":"Craniopharyngioma: Complications and treatment failures weaken case for aggressive surgery","author":"Raimondi","year":"1993","journal-title":"Crit Rev Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-11","first-page":"1350","volume-title":"Neurosurgical treatment of craniopharyngioma in adults and children: Early and long-term results in a large case series","author":"Mortini","year":"2011","journal-title":"J Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-12","first-page":"22","volume-title":"Surgical management of craniopharyngiomas.A review of 74 cases","author":"Baskin","year":"1986","journal-title":"J Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-13","first-page":"6","volume-title":"Outcomes following endoscopic, expanded endonasal resection of suprasellar craniopharyngiomas: A case series","author":"Gardner","year":"2008","journal-title":"J Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-14","first-page":"47","volume-title":"Aggressive surgical management of craniopharyngiomas in children","author":"Hoffman","year":"1992","journal-title":"J Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-15","first-page":"73","volume-title":"Management of childhood craniopharyngioma: Can the morbidity of radical surgery be predicted?","author":"De","year":"1996","journal-title":"J Neurosurg"},{"key":"key-10.4103\/1793-5482.150228-16","unstructured":"Fahlbusch R, Honegger J, Buchfelder M. Clinical features and management of craniopharyngiomas in adults. In: Tindall GT, Cooper PR, Barrow DL, editors. The Practice of Neurosurgery. Baltimore: Williams and Wilkins; 1996. p. 1159-73."},{"key":"key-10.4103\/1793-5482.150228-17","first-page":"1313","volume-title":"The role of radiation therapy in the management of childhood craniopharyngioma","author":"Weiss","year":"1989","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Asian Journal of Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/1793-5482.150228.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T22:46:22Z","timestamp":1663713982000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/1793-5482.150228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":17,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2022,9,20]]},"published-print":{"date-parts":[[2017,9]]}},"URL":"https:\/\/doi.org\/10.4103\/1793-5482.150228","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1793-5482","2248-9614"],"issn-type":[{"value":"1793-5482","type":"print"},{"value":"2248-9614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9]]}}}