{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T02:24:38Z","timestamp":1784168678062,"version":"3.55.0"},"reference-count":51,"publisher":"Medknow","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["North Am J Med Sci"],"published-print":{"date-parts":[[2016]]},"DOI":"10.4103\/1947-2714.179133","type":"journal-article","created":{"date-parts":[[2016,3,21]],"date-time":"2016-03-21T09:06:16Z","timestamp":1458551176000},"page":"156","source":"Crossref","is-referenced-by-count":24,"title":["Safety of 50,000-100,000 units of vitamin D3\/week in vitamin D-deficient, hypercholesterolemic patients with reversible statin intolerance"],"prefix":"10.4103","volume":"8","author":[{"given":"CharlesJ","family":"Glueck","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vybhav","family":"Jetty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parth","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marloe","family":"Prince","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Goldenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwin","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2581","reference":[{"key":"key-10.4103\/1947-2714.179133-1","first-page":"62","volume-title":"Cell defenses and the sunshine vitamin","author":"Tavera-Mendoza","year":"2007","journal-title":"Sci Am"},{"key":"key-10.4103\/1947-2714.179133-2","first-page":"1341","volume-title":"Comparison of oral 25-hydroxycholecalciferol, vitamin D, and ultraviolet light as determinants of circulating 25-hydroxyvitamin D","author":"Stamp","year":"1977","journal-title":"Lancet"},{"key":"key-10.4103\/1947-2714.179133-3","first-page":"842","volume-title":"Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety","author":"Vieth","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/1947-2714.179133-4","first-page":"317","volume-title":"Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: Implications for establishing a new effective dietary intake recommendation for vitamin D","author":"Hollis","year":"2005","journal-title":"J Nutr"},{"key":"key-10.4103\/1947-2714.179133-5","first-page":"266","volume-title":"Vitamin D deficiency","author":"Holick","year":"2007","journal-title":"N Engl J Med"},{"key":"key-10.4103\/1947-2714.179133-6","first-page":"537","volume-title":"The treeatment of arthritis with massive doses of vitamin D","author":"Dreyer","year":"1935","journal-title":"Archives of Physical Therapy"},{"key":"key-10.4103\/1947-2714.179133-7","first-page":"541","volume-title":"The treatment of hay fever and asthma with Viosterol of high potency","author":"Rappaport","year":"1934","journal-title":"J Allergy"},{"key":"key-10.4103\/1947-2714.179133-8","first-page":"225","volume-title":"Lupus vulgaris treated with calciferol","author":"Dowling","year":"1946","journal-title":"Proc R Soc Lond B Biol Sci"},{"key":"key-10.4103\/1947-2714.179133-9","first-page":"149","volume-title":"Vitamin D toxicity","author":"Leake","year":"1936","journal-title":"Cal West Med"},{"key":"key-10.4103\/1947-2714.179133-10","first-page":"367","volume-title":"Lesions following the use of ertron in rheumatoid arthritis","author":"Bevans","year":"1947","journal-title":"Am J Pathol"},{"key":"key-10.4103\/1947-2714.179133-11","first-page":"908","volume-title":"American Academy of Pediatrics.Prevention of rickets and vitamin D deficiency: New guidelines for vitamin D intake","author":"Gartner","year":"2003","journal-title":"Pediatrics"},{"key":"key-10.4103\/1947-2714.179133-12","first-page":"53","volume-title":"The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know","author":"Ross","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"key-10.4103\/1947-2714.179133-13","first-page":"1911","volume-title":"Evaluation, treatment, and prevention of vitamin D deficiency: An endocrine society clinical practice guideline","author":"Holick","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"key-10.4103\/1947-2714.179133-14","first-page":"836","volume-title":"The effect of narrowband UV-B treatment for psoriasis on vitamin D status during wintertime in Ireland","author":"Ryan","year":"2010","journal-title":"Arch Dermatol"},{"key":"key-10.4103\/1947-2714.179133-15","first-page":"204","volume-title":"Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol","author":"Heaney","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/1947-2714.179133-16","first-page":"6","volume-title":"Risk assessment for vitamin D","author":"Hathcock","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/1947-2714.179133-17","first-page":"607","volume-title":"Vitamin D supplement doses and serum 25-hydroxyvitamin D in the range associated with cancer prevention","author":"Garland","year":"2011","journal-title":"Anticancer Res"},{"key":"key-10.4103\/1947-2714.179133-18","first-page":"332","volume-title":"Vitamin D3 supplementation (4000 IU\/d for 1 y) eliminates differences in circulating 25-hydroxyvitamin D between African American and white men","author":"Garrett-Mayer","year":"2012","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/1947-2714.179133-19","first-page":"2315","volume-title":"Vitamin D3 supplementation at 4000 international units per day for one year results in a decrease of positive cores at repeat biopsy in subjects with low-risk prostate cancer under active surveillance","author":"Marshall","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"key-10.4103\/1947-2714.179133-20","first-page":"577","volume-title":"Changing incidence of serum 25-Hydroxyvitamin D values above 50 ng\/mL: A 10-year population-based study","author":"Dudenkov","year":"2015","journal-title":"Mayo Clin Proc"},{"key":"key-10.4103\/1947-2714.179133-21","first-page":"720","volume-title":"Vitamin D for health: A global perspective","author":"Hossein-Nezhad","year":"2013","journal-title":"Mayo Clin Proc"},{"key":"key-10.4103\/1947-2714.179133-22","first-page":"1783","volume-title":"25-Hydroxyvitamin D in the range of 20 to 100 ng\/mL and incidence of kidney stones","author":"Nguyen","year":"2014","journal-title":"Am J Public Health"},{"key":"key-10.4103\/1947-2714.179133-23","first-page":"134","volume-title":"Vitamin D status in patients with recurrent kidney stones","author":"Pipili","year":"2012","journal-title":"Nephron Clin Pract"},{"key":"key-10.4103\/1947-2714.179133-24","first-page":"4385","volume-title":"Association between serum 25-hydroxyvitamin D and nephrolithiasis: The National Health and Nutrition Examination Survey III, 1988-94","author":"Tang","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"key-10.4103\/1947-2714.179133-25","first-page":"1512","volume-title":"Vitamin D repletion does not alter urinary calcium excretion in healthy postmenopausal women","author":"Penniston","year":"2009","journal-title":"BJU Int"},{"key":"key-10.4103\/1947-2714.179133-26","first-page":"658","volume-title":"Symptomatic myositis-myalgia in hypercholesterolemic statin-treated patients with concurrent vitamin D deficiency leading to statin intolerance may reflect a reversible interaction between vitamin D deficiency and statins on skeletal muscle","author":"Glueck","year":"2011","journal-title":"Med Hypotheses"},{"key":"key-10.4103\/1947-2714.179133-27","first-page":"11","volume-title":"Low serum 25(OH) vitamin D levels (<32 ng\/mL) are associated with reversible myositis-myalgia in statin-treated patients","author":"Ahmed","year":"2009","journal-title":"Transl Res"},{"key":"key-10.4103\/1947-2714.179133-28","first-page":"1683","volume-title":"Vitamin D deficiency, myositis-myalgia, and reversible statin intolerance","author":"Glueck","year":"2011","journal-title":"Curr Med Res Opin"},{"key":"key-10.4103\/1947-2714.179133-29","first-page":"48","volume-title":"Management of the patient with statin intolerance","author":"Vandenberg","year":"2010","journal-title":"Curr Atheroscler Rep"},{"key":"key-10.4103\/1947-2714.179133-30","first-page":"526","volume-title":"Discontinuation of statins in routine care settings: A cohort study","author":"Zhang","year":"2013","journal-title":"Ann Intern Med"},{"key":"key-10.4103\/1947-2714.179133-31","first-page":"625","volume-title":"Statin therapy, muscle function and falls risk in community-dwelling older adults","author":"Scott","year":"2009","journal-title":"QJM"},{"key":"key-10.4103\/1947-2714.179133-32","first-page":"e88877","volume-title":"Association of vitamin D and incident statin induced myalgia - A retrospective cohort study","author":"Palamaner","year":"2014","journal-title":"PLoS One"},{"key":"key-10.4103\/1947-2714.179133-33","first-page":"154","volume-title":"Vitamin D insufficiency - A novel mechanism of statin-induced myalgia?","author":"Lee","year":"2009","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key-10.4103\/1947-2714.179133-34","first-page":"380","volume-title":"Resolution of statin-induced myalgias by correcting vitamin D deficiency","author":"Fang","year":"2011","journal-title":"South Med J"},{"key":"key-10.4103\/1947-2714.179133-35","first-page":"690","volume-title":"Resolution of statin-induced myalgias by correcting vitamin D deficiency","author":"Bell","year":"2010","journal-title":"South Med J"},{"key":"key-10.4103\/1947-2714.179133-36","doi-asserted-by":"crossref","unstructured":"Mergenhagen K, Ott M, Heckman K, Rubin LM, Kellick K. Low vitamin D as a risk factor for the development of myalgia in patients taking high-dose simvastatin: A retrospective review. Clin Ther 2014;36:770-7.","DOI":"10.1016\/j.clinthera.2014.02.023"},{"key":"key-10.4103\/1947-2714.179133-37","first-page":"77","volume-title":"The role of vitamin D and SLCO1B1FNx015 gene polymorphism in statin-associated myalgias","author":"Linde","year":"2010","journal-title":"Dermatoendocrinol"},{"key":"key-10.4103\/1947-2714.179133-38","first-page":"36","volume-title":"Muscle pain and serum creatine kinase are not associated with low serum 25(OH) vitamin D levels in patients receiving statins","author":"Kurnik","year":"2012","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key-10.4103\/1947-2714.179133-39","first-page":"1247","volume-title":"Myopathy during statin therapy in the daily practice of an outpatient cardiology clinic: Prevalence, predictors and relation with vitamin D","author":"Riphagen","year":"2012","journal-title":"Curr Med Res Opin"},{"key":"key-10.4103\/1947-2714.179133-40","first-page":"42","volume-title":"Low plasma vitamin D levels and muscle-related adverse effects in statin users","author":"Eisen","year":"2014","journal-title":"Isr Med Assoc J"},{"key":"key-10.4103\/1947-2714.179133-41","first-page":"1681","volume-title":"Statin-associated myopathy","author":"Thompson","year":"2003","journal-title":"JAMA"},{"key":"key-10.4103\/1947-2714.179133-42","first-page":"1133","volume-title":"High prevalence of vitamin D deficiency, secondary hyperparathyroidism and generalized bone pain in Turkish immigrants in Germany: Identification of risk factors","author":"Erkal","year":"2006","journal-title":"Osteoporos Int"},{"key":"key-10.4103\/1947-2714.179133-43","first-page":"297","volume-title":"Vitamin d and rehabilitation: Improving functional outcomes","author":"Shinchuk","year":"2007","journal-title":"Nutr Clin Pract"},{"key":"key-10.4103\/1947-2714.179133-44","first-page":"746","volume-title":"Effects of vitamin D supplementation and exercise training on physical performance in Chilean vitamin D deficient elderly subjects","author":"Bunout","year":"2006","journal-title":"Exp Gerontol"},{"key":"key-10.4103\/1947-2714.179133-45","first-page":"752","volume-title":"Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or = 60 y","author":"Bischoff-Ferrari","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/1947-2714.179133-46","first-page":"4","volume-title":"Vitamin D physiology","author":"Lips","year":"2006","journal-title":"Prog Biophys Mol Biol"},{"key":"key-10.4103\/1947-2714.179133-47","first-page":"494","volume-title":"Severe vitamin d deficiency, myopathy, and rhabdomyolysis","author":"Glueck","year":"2013","journal-title":"N Am J Med Sci"},{"key":"key-10.4103\/1947-2714.179133-48","first-page":"86","volume-title":"Statin intolerance because of myalgia, myositis, myopathy, or myonecrosis can in most cases be safely resolved by vitamin D supplementation","author":"Khayznikov","year":"2015","journal-title":"N Am J Med Sci"},{"key":"key-10.4103\/1947-2714.179133-49","first-page":"3001","volume-title":"Determination of 25-hydroxyvitamin D in human plasma using high-performance liquid chromatography - tandem mass spectrometry","author":"Tsugawa","year":"2005","journal-title":"Anal Chem"},{"key":"key-10.4103\/1947-2714.179133-50","first-page":"111","volume-title":"Analysis of vitamin D levels in patients with and without statin-associated myalgia - A systematic review and meta-analysis of 7 studies with 2420 patients","author":"Michalska-Kasiczak","year":"2015","journal-title":"Int J Cardiol"},{"key":"key-10.4103\/1947-2714.179133-51","first-page":"227","volume-title":"; National Heart, Lung, and Blood Institute; American College of Cardiology Foundation; American Heart Association.Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines","author":"Grundy","year":"2004","journal-title":"Circulation"}],"container-title":["North American Journal of Medical Sciences"],"original-title":[],"language":"en","deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T04:56:17Z","timestamp":1498280177000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.najms.org\/text.asp?2016\/8\/3\/156\/179133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":51,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016]]}},"alternative-id":["179133"],"URL":"https:\/\/doi.org\/10.4103\/1947-2714.179133","relation":{},"ISSN":["1947-2714"],"issn-type":[{"value":"1947-2714","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}