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We describe a single\u2010center experience of three patients with severe Group 1\u00a0PAH, refractory to targeted medical therapy, in which an extubated, nonsedated, extracorporeal membrane oxygenation (ECMO) strategy with an upper\u2010body configuration was used as a bridge to recovery or lung transplantation. All three patients were extubated within 24 hours of ECMO initiation. Two patients were successfully bridged to lung transplantation, and the other patient was optimized on targeted PAH therapy with subsequent recovery from an acute decompensation. The upper\u2010body ECMO configuration allowed for daily physical therapy, including one patient, who would otherwise have been unsuitable for transplantation, ambulating over 850\u00a0meters daily. This series demonstrates the feasibility of using ECMO to bridge PAH patients to recovery or transplantation while avoiding the complications of immobility and invasive mechanical ventilation.<\/jats:p>","DOI":"10.4103\/2045-8932.113178","type":"journal-article","created":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T09:01:27Z","timestamp":1373274087000},"page":"432-435","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":60,"title":["Upper\u2010Body Extracorporeal Membrane Oxygenation as a Strategy in Decompensated Pulmonary Arterial Hypertension"],"prefix":"10.1002","volume":"3","author":[{"given":"Darryl C.","family":"Abrams","sequence":"first","affiliation":[{"name":"Division of Pulmonary Allergy, and Critical Care Department of Medicine New York City New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Brodie","sequence":"additional","affiliation":[{"name":"Division 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