{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T01:43:55Z","timestamp":1792287835050,"version":"4.4.0"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Gas Res"],"published-print":{"date-parts":[[2018]]},"DOI":"10.4103\/2045-9912.241063","type":"journal-article","created":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T03:54:18Z","timestamp":1537847658000},"page":"73","source":"Crossref","is-referenced-by-count":15,"title":["Inhalation of high concentration hydrogen gas improves short-term outcomes in a rat model of asphyxia induced-cardiac arrest"],"prefix":"10.4103","volume":"8","author":[{"given":"Lei","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RichardL","family":"Applegate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PatriciaM","family":"Applegate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren","family":"Boling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JohnH","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/2045-9912.241063-1","first-page":"213","volume-title":"Brain function after resuscitation from cardiac arrest.Curr Opin Crit Care","author":"Madl","year":"2004","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-2","first-page":"530","volume-title":"Long-term outcome after survival of a cardiac arrest: a prospective longitudinal cohort study.Neurorehabil Neural Repair","author":"Moulaert","year":"2017","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-3","first-page":"e28","volume-title":"Heart disease and stroke statistics--2014 update: a report from the American Heart Association.Circulation","author":"Go","year":"2014","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-4","first-page":"I1","volume-title":"Circulation","author":"Part","year":"2000","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-5","first-page":"784","volume-title":"Cardiocerebral resuscitation vs cardiopulmonary resuscitation for cardiac arrest: a systematic review.Am J Emerg Med","author":"Yang","year":"2012","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-6","first-page":"688","volume-title":"Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.Nat Med","author":"Ohsawa","year":"2007","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-7","first-page":"32","volume-title":"Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.BMC Cardiovasc Disord","author":"Fan","year":"2018","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-8","first-page":"971","volume-title":"Recent advances in hydrogen research as a therapeutic medical gas.Free Radic Res","author":"Huang","year":"2010","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-9","first-page":"402","volume-title":"Hydrogen gas reduced acute hyperglycemia-enhanced hemorrhagic transformation in a focal ischemia rat model.Neuroscience","author":"Chen","year":"2010","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-10","first-page":"1291","volume-title":"Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.Crit Care Med","author":"Zhan","year":"2012","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-11","first-page":"1","volume-title":"Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine.Pharmacol Ther","author":"Ohta","year":"2014","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-12","first-page":"164","volume-title":"The production of high dose hydrogen gas by the AMS-H-01 for treatment of disease.Med Gas Res","author":"Camara","year":"2016","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-13","first-page":"232","volume-title":"Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use.Neuroscience","author":"Cui","year":"2016","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-14","first-page":"83","volume-title":"Inhalation of high concentrations of hydrogen ameliorates liver ischemia\/reperfusion injury through A2A receptor mediated PI3K-Akt pathway.Biochem Pharmacol","author":"Li","year":"2017","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-15","first-page":"1309","volume-title":"Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model.Int J Chron Obstruct Pulmon Dis","author":"Liu","year":"2017","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-16","first-page":"2680","volume-title":"Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice.Int J Clin Exp Pathol","author":"Peng","year":"2015","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-17","first-page":"82","volume-title":"Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia\/reperfusion injury.Brain Res","author":"Wang","year":"2016","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-18","first-page":"368","volume-title":"Hydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats.Anesth Analg","author":"Huo","year":"2014","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-19","doi-asserted-by":"crossref","unstructured":"Hendrickx HH, Rao GR, Safar P, Gisvold SE. Asphyxia, cardiac arrest and resuscitation in rats. I. Short term recovery. Resuscitation. 1984;12:97-116.","DOI":"10.1016\/0300-9572(84)90062-5"},{"key":"key-10.4103\/2045-9912.241063-20","first-page":"293","volume-title":"Neuroprotective strategies in Parkinson\u2019s disease: protection against progressive nigral damage induced by free radicals.Neurotox Res","author":"Chiueh","year":"2000","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-21","first-page":"90","volume-title":"Cilnidipine mediates a neuroprotective effect by scavenging free radicals and activating the phosphatidylinositol 3-kinase pathway.J Neurochem","author":"Lee","year":"2009","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-22","first-page":"e003459","volume-title":"H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model.J Am Heart Assoc","author":"Hayashida","year":"2012","journal-title":""},{"key":"key-10.4103\/2045-9912.241063-23","first-page":"2173","volume-title":"Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management.Circulation","author":"Hayashida","year":"2014","journal-title":""}],"container-title":["Medical Gas Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T18:38:18Z","timestamp":1786732698000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/2045-9912.241063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018]]}},"alternative-id":["241063"],"URL":"https:\/\/doi.org\/10.4103\/2045-9912.241063","relation":{},"ISSN":["2045-9912"],"issn-type":[{"value":"2045-9912","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}