{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T07:41:16Z","timestamp":1772696476450,"version":"3.50.1"},"reference-count":28,"publisher":"Scientific Scholar","content-domain":{"domain":["clinicalimagingscience.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Objective:<\/jats:title>\n<jats:p>Characterization of magnetic (MRI) features in women undergoing uterine fibroid embolization (UFE) and identification of clinical correlates in an African population.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Materials and Methods:<\/jats:title>\n<jats:p>Patients with symptomatic fibroids who are selected to undergo UFE at the hospital formed the study population. The baseline MRI features, baseline symptom score, short-term imaging outcome, and mid-term symptom scores were analyzed for interval changes. Assessment of potential associations between short-term imaging features and mid-term symptom scores was also done.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Results:<\/jats:title>\n<jats:p>UFE resulted in statistically significant reduction (<jats:italic>P<\/jats:italic> &lt; 0.001) of dominant fibroid, uterine volumes, and reduction of symptom severity scores, which were 43.7%, 40.1%, and 37.8%, respectively. Also, 59% of respondents had more than 10 fibroids. The predominant location of the dominant fibroid was intramural. No statistically significant association was found between clinical and radiological outcome.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>The response of uterine fibroids to embolization in the African population is not different from the findings reported in other studies from the west. The presence of multiple and large fibroids in this study is consistent with the case mix described in other studies of African-American populations. Patient counseling should emphasize the independence of volume reduction and symptom improvement. Though volume changes are of relevance for the radiologist in understanding the evolution of the condition and identifying potential technical treatment failures, it should not be the main basis of evaluation of treatment success.<\/jats:p>\n<\/jats:sec>","DOI":"10.4103\/2156-7514.154351","type":"journal-article","created":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:36:14Z","timestamp":1427848574000},"page":"18","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Uterine Fibroid Embolization for Symptomatic Fibroids: Study at a Teaching Hospital in Kenya"],"prefix":"10.25259","volume":"5","author":[{"given":"John Kiprop","family":"Mutai","sequence":"first","affiliation":[{"name":"Department of Radiology, Aga Khan University Hospital, Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudhir","family":"Vinayak","sequence":"additional","affiliation":[{"name":"Department of Radiology, Aga Khan University Hospital, Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Stones","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, University of Malawi, Blantyre, Malawi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nigel","family":"Hacking","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, University Hospital Southampton NHS Foundation Trust (UHS), UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Mariara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Aga Khan University Hospital, Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2015,3,31]]},"reference":[{"key":"10.4103\/2156-7514.154351\/ref-1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1097\/00001703-199306000-00003","article-title":"Changing trends in treatment of leiomyomata uteri","volume":"5","author":"VerKauf","year":"1993","journal-title":"Curr Opin Obstet Gynecol"},{"key":"10.4103\/2156-7514.154351\/ref-2","doi-asserted-by":"crossref","first-page":"852","DOI":"10.2105\/AJPH.78.7.852","article-title":"Hysterectomy in the United States, 1965-84","volume":"78","author":"Pokras","year":"1988","journal-title":"Am J Public Health"},{"key":"10.4103\/2156-7514.154351\/ref-3","first-page":"188","article-title":"Indications and results of total hysterectomy","volume":"71","author":"Chryssikopoulos","year":"1986","journal-title":"Int Surg"},{"key":"10.4103\/2156-7514.154351\/ref-4","first-page":"290","article-title":"The UFS-QOL, a new disease-specific symptom and health-related quality of life questionnaire for leiomyomata","volume":"99","author":"Spies","year":"2002","journal-title":"Obstet Gynecol"},{"key":"10.4103\/2156-7514.154351\/ref-5","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/01.AOG.0000136079.62513.39","article-title":"Uterine myomas: An overview of development, clinical features, and management","volume":"104","author":"Wallach","year":"2004","journal-title":"Obstet Gynecol"},{"key":"10.4103\/2156-7514.154351\/ref-6","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1016\/j.ajog.2004.12.083","article-title":"Benign gynaecologic conditions among participants in the Breast Cancer Prevention Trial","volume":"192","author":"Chalas","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.4103\/2156-7514.154351\/ref-7","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1097\/01.AOG.0000154161.03418.e3","article-title":"Age-specific incidence rates for self-reported uterine leiomyomata in the Black Women's Health Study","volume":"105","author":"Wise","year":"2005","journal-title":"Obstet Gynecol"},{"key":"10.4103\/2156-7514.154351\/ref-8","first-page":"483","article-title":"Uterine leiomyomas. 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