{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T14:22:13Z","timestamp":1744035733921},"reference-count":10,"publisher":"Scientific Scholar","content-domain":{"domain":["clinicalimagingscience.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>Pachygyria is considered a subtype of lissencephaly which, in turn, is a spectrum of disorders caused by abnormal neuronal migration. Clinical presentation in this disorder may be varied including microcephaly, developmental delay, facial dysmorphism, seizures, and mental retardation. Magnetic resonance imaging (MRI) of brain identifies the exact nature and extent of the disease and helps in delineating further plan of management. A Tigroid pattern on axial MRI scan and leopard pattern on a sagittal plane has been classically reported in disorders of myelin formation such as metachromatic leukodystrophy and Pelizaeus\u2013Merzbacher disease. We present here a case of pachygyria who presented to us with some atypical features including \u201ctigroid-like stripes\u201d and \u201cleopard-like pattern\u201d on MRI brain which has not been reported in the medical literature previously.<\/jats:p>","DOI":"10.4103\/2156-7514.181491","type":"journal-article","created":{"date-parts":[[2016,4,29]],"date-time":"2016-04-29T10:01:46Z","timestamp":1461924106000},"page":"15","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["\u201cReverse Tigroid\u201d Pattern in Pachygyria: A Novel Finding"],"prefix":"10.25259","volume":"6","author":[{"given":"Ujjawal","family":"Roy","sequence":"first","affiliation":[{"name":"Department of Neurology, Bangur Institute of Neurosciences, IPGMER, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alak","family":"Pandit","sequence":"additional","affiliation":[{"name":"Department of Neurology, Bangur Institute of Neurosciences, IPGMER, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urmila","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Neurology, Bangur Institute of Neurosciences, IPGMER, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay","family":"Panwar","sequence":"additional","affiliation":[{"name":"Department of Neurology, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2016,4,29]]},"reference":[{"issue":"Pt 5","key":"10.4103\/2156-7514.181491\/ref-1","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1093\/brain\/aws019","article-title":"A developmental and genetic classification for malformations of cortical development: Update 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disease","volume":"44","author":"Biancheri","year":"2013","journal-title":"Neuropediatrics"},{"key":"10.4103\/2156-7514.181491\/ref-9","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jocn.2008.02.011","article-title":"Tigroid pattern on magnetic resonance imaging in Lowe syndrome","volume":"16","author":"Onur","year":"2009","journal-title":"J Clin Neurosci"},{"key":"10.4103\/2156-7514.181491\/ref-10","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1007\/s00247-008-0909-7","article-title":"Tigroid pattern of the white matter: A previously unrecognized MR finding in lissencephaly with cerebellar hypoplasia","volume":"38","author":"Kono","year":"2008","journal-title":"Pediatr Radiol"}],"container-title":["Journal of Clinical Imaging 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