{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T15:12:09Z","timestamp":1769094729892,"version":"3.49.0"},"reference-count":10,"publisher":"Scientific Scholar","content-domain":{"domain":["clinicalimagingscience.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>A well-proportioned face combines features that are balanced and symmetrical. Any structural alteration that leads to facial asymmetry causes esthetical and psychological disturbances. Lipoatrophy is one such condition, which results in loss of subcutaneous fat layer and manifests as a depression. Although many subtypes with varying clinical and etiological backgrounds exist, the idiopathic form is rare and facial involvement is the rarest. Computed tomography is one of the accepted diagnostic tools to determine the atrophic layer of facial anatomy. This report presents the clinical types, diagnosis, and management of a case of facial lipoatrophy.<\/jats:p>","DOI":"10.4103\/2156-7514.94229","type":"journal-article","created":{"date-parts":[[2012,3,23]],"date-time":"2012-03-23T09:08:53Z","timestamp":1332493733000},"page":"14","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Focal Lipoatrophy of Face: A Rare Esthetic Complaint"],"prefix":"10.25259","volume":"2","author":[{"given":"K.","family":"Anbarasi","sequence":"first","affiliation":[{"name":"Division of Oral Medicine and Radiology, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Sathasivasubramanian","sequence":"additional","affiliation":[{"name":"Division of Oral Medicine and Radiology, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. L.","family":"Krithika","sequence":"additional","affiliation":[{"name":"Division of Radiology, Sri Ramachandra University, Porur, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. M.","family":"VenkataSai","sequence":"additional","affiliation":[{"name":"Division of Radiology, Sri Ramachandra University, Porur, Chennai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2012,3,22]]},"reference":[{"key":"10.4103\/2156-7514.94229\/ref-1","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1530\/eje.0.1430565","article-title":"Discovery of a lipoatrophy gene.One answer, one hundred questions","volume":"143","author":"Shalev","year":"2000","journal-title":"Eur J Endocrinol"},{"key":"10.4103\/2156-7514.94229\/ref-2","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.beem.2010.12.001","article-title":"Adipose tissue biology and HIV- infection","volume":"25","author":"Giralt","year":"2011","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.4103\/2156-7514.94229\/ref-3","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/00000441-188507000-00006","article-title":"Singular case of absence of adipose matter in the upper half of the body","volume":"90","author":"Mitchell","year":"1885","journal-title":"Am J Med Sci"},{"key":"10.4103\/2156-7514.94229\/ref-4","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.2337\/diacare.19.11.1283","article-title":"Insulin - induced lipoatrophy in type I diabetes: A possible tumor necrosis factor- \u03b1 mediated differentiation of adipocytes","volume":"19","author":"Atlan-Gepner","year":"1996","journal-title":"Diabetes Care"},{"key":"10.4103\/2156-7514.94229\/ref-5","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1097\/00002030-199911120-00008","article-title":"Subcutaneous adipocyte apoptosis in HIV - 1 Protease inhibitor associated Lipodystrophy","volume":"13","author":"Domingo","year":"1999","journal-title":"AIDS"},{"key":"10.4103\/2156-7514.94229\/ref-6","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1111\/j.1346-8138.2002.tb00194.x","article-title":"Localized involutional lipoatrophy: Report of six cases","volume":"29","author":"Yamamoto","year":"2002","journal-title":"J Dermatol"},{"key":"10.4103\/2156-7514.94229\/ref-7","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/archderm.1980.01640360037014","article-title":"Localized lipoatrophy (atrophic connective tissue disease panniculitis)","volume":"116","author":"Peters","year":"1980","journal-title":"Arch Dermatol"},{"key":"10.4103\/2156-7514.94229\/ref-8","first-page":"1058","article-title":"Full scope of effect of facial lipoatrophy: A framework of disease understanding","volume":"32","author":"Ascher","year":"2006","journal-title":"Dermatol Surg"},{"key":"10.4103\/2156-7514.94229\/ref-9","first-page":"167","article-title":"New and emerging agents in the management of lipodystrophy in HIV-infected patients","volume":"2","author":"Bonnet","year":"2010","journal-title":"HIV\/AIDS"},{"key":"10.4103\/2156-7514.94229\/ref-10","first-page":"66","article-title":"A case of fat injection for treating subcutaneous atrophy caused by local administration of corticosteroid","volume":"35","author":"Imagawa","year":"2010","journal-title":"Tokai J Exp Clin Med"}],"container-title":["Journal of Clinical Imaging Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/clinicalimagingscience.org\/focal-lipoatrophy-of-face-a-rare-esthetic-complaint\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/clinicalimagingscience.org\/focal-lipoatrophy-of-face-a-rare-esthetic-complaint\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T04:59:48Z","timestamp":1567141188000},"score":1,"resource":{"primary":{"URL":"https:\/\/clinicalimagingscience.org\/focal-lipoatrophy-of-face-a-rare-esthetic-complaint\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,22]]},"references-count":10,"alternative-id":["10.4103\/2156-7514.94229"],"URL":"https:\/\/doi.org\/10.4103\/2156-7514.94229","relation":{},"ISSN":["2156-7514"],"issn-type":[{"value":"2156-7514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,22]]},"article-number":"14"}}