{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:19:14Z","timestamp":1787761154507,"version":"build-2784847793"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>We report a case of Fuchs endothelial corneal dystrophy (FECD) with concurrent forme fruste keratoconus (KCN) that was unmasked with Descemet membrane endothelial keratoplasty (DMEK) in the right eye, but not with Descemet-stripping automated endothelial keratoplasty (DSAEK) in the left eye. The patient was a 65-year-old female with FECD who underwent uncomplicated combination cataract surgery and DMEK in the right eye. She subsequently developed intractable monocular diplopia associated with inferior displacement of the thinnest point of the cornea and subtle steepening noted on posterior corneal curvature on Scheimpflug tomography. The patient was diagnosed with forme fruste KCN. Altering the surgical plan to combine cataract surgery and DSAEK in the left eye successfully circumvented the development of symptomatic visual distortion. This is the first case providing comparable data from contralateral eyes in the same patient regarding the outcome of DMEK versus DSAEK in eyes with concurrent forme fruste KCN. DMEK appeared to unmask posterior corneal irregularities and resulted in visual distortion, whereas DSAEK did not. The additional stromal tissue in DSAEK grafts appears to help normalize alterations of the posterior corneal curvature and may be the preferred endothelial keratoplasty for patients with concurrent mild KCN.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/2211-5056.363562","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T02:33:53Z","timestamp":1670985233000},"page":"110-113","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Unmasking of subclinical keratoconus with Descemet membrane endothelial keratoplasty in Fuchs endothelial dystrophy"],"prefix":"10.4103","volume":"13","author":[{"given":"Madeline","family":"Yung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer Y.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20-20240830","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0039-6257(97)00119-7","article-title":"Keratoconus","volume":"42","author":"Rabinowitz","year":"1998","journal-title":"Surv Ophthalmol"},{"key":"R2-20-20240830","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1016\/S0161-6420(02)01121-1","article-title":"Role of Orbscan II in screening keratoconus suspects before refractive corneal surgery","volume":"109","author":"Rao","year":"2002","journal-title":"Ophthalmology"},{"key":"R3-20-20240830","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1016\/j.ophtha.2009.06.021","article-title":"Descemet's stripping endothelial keratoplasty: Safety and outcomes: A report by the American Academy of Ophthalmology","volume":"116","author":"Lee","year":"2009","journal-title":"Ophthalmology"},{"key":"R4-20-20240830","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.ophtha.2017.08.015","article-title":"Descemet membrane endothelial keratoplasty: Safety and outcomes: A Report by the American Academy of Ophthalmology","volume":"125","author":"Deng","year":"2018","journal-title":"Ophthalmology"},{"key":"R5-20-20240830","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/ICO.0000000000002796","article-title":"Descemet stripping only for Fuchs endothelial corneal dystrophy: Will it become the gold standard?","volume":"41","author":"Colby","year":"2022","journal-title":"Cornea"},{"key":"R6-20-20240830","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1159\/000505579","article-title":"Comorbidity of keratoconus and Fuchs' corneal endothelial dystrophy: A review of the literature","volume":"63","author":"Mylona","year":"2020","journal-title":"Ophthalmic Res"},{"key":"R7-20-20240830","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0002-9394(14)76210-5","article-title":"Identifying progression of subclinical keratoconus by serial topography analysis","volume":"112","author":"Maguire","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"R8-20-20240830","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0002-9394(89)90001-9","article-title":"Corneal topography of early keratoconus","volume":"108","author":"Maguire","year":"1989","journal-title":"Am J Ophthalmol"},{"key":"R9-20-20240830","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1097\/ICO.0000000000001909","article-title":"Keratoconus corneal posterior surface characterization according to the degree of visual limitation","volume":"38","author":"Vega-Estrada","year":"2019","journal-title":"Cornea"},{"key":"R10-20-20240830","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1016\/j.ophtha.2008.02.020","article-title":"Sensitivity and specificity of posterior corneal elevation measured by Pentacam in discriminating keratoconus\/subclinical keratoconus","volume":"115","author":"de Sanctis","year":"2008","journal-title":"Ophthalmology"},{"key":"R11-20-20240830","doi-asserted-by":"crossref","first-page":"972","DOI":"10.3928\/1081597X-20100212-08","article-title":"Pentacam characterization of corneas with Fuchs dystrophy treated with Descemet membrane endothelial keratoplasty","volume":"26","author":"Kwon","year":"2010","journal-title":"J Refract Surg"},{"key":"R12-20-20240830","doi-asserted-by":"crossref","first-page":"299","DOI":"10.3928\/1081597X-20100525-02","article-title":"Is excimer laser corneal surgery appropriate after resolution of corneal edema in Fuchs dystrophy by descemet membrane endothelial keratoplasty?","volume":"27","author":"Price","year":"2011","journal-title":"J Refract Surg"},{"key":"R14-20-20240830","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/ICO.0b013e3182a7389c","article-title":"Descemet stripping endothelial keratoplasty for the treatment of combined Fuchs corneal endothelial dystrophy and keratoconus","volume":"33","author":"Vira","year":"2014","journal-title":"Cornea"},{"key":"R15-20-20240830","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1097\/ICO.0000000000001309","article-title":"Elimination of anterior corneal steepening with Descemet membrane endothelial keratoplasty in a patient with Fuchs dystrophy and keratoconus: Implications for IOL calculation","volume":"36","author":"Gupta","year":"2017","journal-title":"Cornea"}],"container-title":["Taiwan Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/2211-5056.363562","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:25:03Z","timestamp":1787757903000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/2211-5056.363562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/2211-5056.363562","relation":{},"ISSN":["2211-5056"],"issn-type":[{"value":"2211-5056","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}