{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:31:51Z","timestamp":1786649511805,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:p>Primary hyperparathyroidism is a disease characterized by excessive secretion of parathormone. During the course of this disease, bone loss occurs, particularly depending on resorption of the skeletal system. One of the complications of primary hyperparathyroidism is fibrotic, cystic bony changes which is called Brown tumor. Skeletal manifestations in the form of Brown tumors are rare and according to literature occur in less than 2% of patients suffering from any form of hyperparathyroidism. Such rare and multiple benign lesions may simulate a malignant neoplasm and pose a real challenge for the clinician in its differential diagnosis. We present a case of a 23-year-old Indian woman who was evaluated for multiple lytic expansile lesions with a strong suspicion of malignancy and fibrous dysplasia but turned out to be a case of primary hyperparathyroidism.<\/jats:p>","DOI":"10.4103\/2230-8210.103037","type":"journal-article","created":{"date-parts":[[2012,10,31]],"date-time":"2012-10-31T06:32:19Z","timestamp":1351665139000},"page":"1040-1042","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":30,"title":["Primary hyperparathyroidism having multiple Brown tumors mimicking malignancy"],"prefix":"10.4103","volume":"16","author":[{"given":"Ekram","family":"Ullah","sequence":"first","affiliation":[{"name":"Department of Radiodiagnosis, Jawaharlal Nehru Medical College, A.M.U. Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehtab","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Jawaharlal Nehru Medical College, A.M.U. Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Asmat","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Surgery, Jawaharlal Nehru Medical College, A.M.U. Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navneet","family":"Redhu","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Jawaharlal Nehru Medical College, A.M.U. Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20260327","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0039-6109(16)41237-5","article-title":"The pathology and surgical management of primary Hyperparathyroidism","volume":"57","author":"Van Herden","year":"1977","journal-title":"Surg Clin North Am"},{"key":"R2-20260327","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1080\/02841850802314788","article-title":"Enhanced FDG uptake in brown tumors mimics multiple skeletal metastases in a patient with primary hyperparathyroidism","volume":"49","author":"Hsu","year":"2008","journal-title":"Acta Radiol"},{"key":"R3-20260327","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jbspin.2007.03.004","article-title":"An unusual presentation of primary Hyperparathyroidism: Severe hypercalcemia and multiple brown tumors","volume":"75","author":"Jouan","year":"2008","journal-title":"Joint Bone Spine"},{"key":"R4-20260327","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1097\/00003072-199407000-00016","article-title":"Multiple brown tumors in hyperparathyroidism mimicking metastatic disease on radiograph and bone scan","volume":"19","author":"Joyce","year":"1994","journal-title":"Clin Nucl Med"},{"key":"R5-20260327","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1007\/BF03347558","article-title":"Multiple brown tumors of the ribs simulating malingnancy","volume":"28","author":"Kalambokis","year":"2005","journal-title":"J Endocrinol Invest"},{"key":"R6-20260327","first-page":"1140","article-title":"Clinical significance of solitary rib lesions in patients with extra skeletal malignancy","volume":"26","author":"Tumeh","year":"1985","journal-title":"J NucI Med"},{"key":"R7-20260327","first-page":"155","article-title":"Multiple maxillofacial brown tumorsas primary hyperparathyroidism manifestation","volume":"144","author":"Res\u00e9ndiz-Colosia","year":"2008","journal-title":"Gac Med Mex"}],"container-title":["Indian Journal of Endocrinology and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/02223308-201216060-00036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:54:54Z","timestamp":1786647294000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/02223308-201216060-00036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.4103\/2230-8210.103037","relation":{},"ISSN":["2230-8210","2230-9500"],"issn-type":[{"value":"2230-8210","type":"print"},{"value":"2230-9500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}