{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:36:55Z","timestamp":1786649815980,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>Hyperparathyroidism (HPT) is a condition that occurs due to exacerbated activity of the parathyroid glands. According to the etiology it may be primary, secondary or tertiary hyperparathyroidism (pHPT, sHPT, tHPT). This is a study done to document and evaluate the presentations of primary and secondary HPT, with the associated complications and the approach to management in these patients, at our hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Twenty-one patients with HPT were encountered at Sri Ramachandra Medical College and Research Institute between January 2000 and January 2010. Operative notes, histopathology files, and medical records were used for the retrospective analysis of the patients with HPT. Parathormone, calcium, and phosphate levels were estimated on all the patients, to determine the primary or secondary etiology of this endocrine abnormality. Furthermore, these patients were subjected to ultrasonography (USG) of the neck and Technetium (99 mTc) scan of the neck to identify the parathyroid gland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>This study revealed that about 76, 19, and 5% of the patients suffered from pHPT, sHPT, and tHPT, respectively, with a female preponderance (62%).The neoplasm in all patients with pHPT was parathyroid adenoma. The patients presented with renal, bony, and menstrual abnormalities. Cases with sHPT had a 15 \u2013 20 year history of chronic kidney disease and they subsequently developed bony abnormalities. Even as all the patients with pHPT were managed with parathyroidectomy, individuals with sHPT were treated conservatively. Postoperative features of hypocalcemia were noted in only one patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study re-emphasizes that pHPT is more common and is often due to an adenoma. Recent advances in parathormone sampling operatively and minimal access surgery, along with accurate and prompt clinical diagnosis, is necessary for the cure of these patients presenting with obscure abdominal, bony, and renal ailments.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/2230-8210.83405","type":"journal-article","created":{"date-parts":[[2011,7,30]],"date-time":"2011-07-30T07:11:12Z","timestamp":1312009872000},"page":"194-197","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Hyperparathyroidism revisited \u2014 Old wine in new bottles!"],"prefix":"10.4103","volume":"15","author":[{"given":"Rekha","family":"Arcot","sequence":"first","affiliation":[{"name":"Department of General Surgery, Sri Ramachandra Medical College and Research Institute, Porur, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujatha Narayana","family":"Moorthy","sequence":"additional","affiliation":[{"name":"Department of Intern, Sri Ramachandra Medical College and Research Institute, Porur, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalinee","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Pathology, Sri Ramachandra Medical College and Research Institute, Porur, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20260327","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0140-6736(09)60507-9","article-title":"Hyperparathyroidism","volume":"374","author":"Fraser","year":"2009","journal-title":"Lancet"},{"key":"R2-20260327","first-page":"649","article-title":"Parathyroid carcinoma versus parathyroid adenoma in patients with profound hypercalcaemia","volume":"101","author":"Levin","year":"1987","journal-title":"Surgery"},{"key":"R3-20260327","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0889-8529(18)30360-8","article-title":"Primary hyperparathyroidism- A surgical perspective","volume":"18","author":"Clark","year":"1989","journal-title":"Endocrinol Metab Clin North Am"},{"key":"R4-20260327","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1210\/jc.2008-1761","article-title":"Surgery for asymptomatic primary hyperparathyroidism: Proceedings of the third international workshop","volume":"94","author":"Udelsman","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"R5-20260327","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/S0039-6060(99)70053-X","article-title":"The evolution of parathyroidectomy failures","volume":"126","author":"Boggs","year":"1999","journal-title":"Surgery"},{"key":"R6-20260327","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1309\/RU5LDXWR1QNQA5WY","article-title":"Rapid intraoperative parathyroid hormone testing with surgical pathology correlations: The \u201cchemical frozen section\u201d","volume":"122","author":"Guarda","year":"2004","journal-title":"Am J Clin Pathol"},{"key":"R7-20260327","first-page":"70","article-title":"The parathyroid adenoma.A histopathologic definition with a study of 172 cases of primary hyperparathyroidism","volume":"115","author":"Ghandur-Mnaymneh","year":"1984","journal-title":"Am J Pathol"},{"key":"R8-20260327","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.suc.2004.01.002","article-title":"Minimal-access\/minimally invasive parathyroidectomy for primary hyperparathyroidism","volume":"84","author":"Fausto Palazzo","year":"2004","journal-title":"Surg Clin N Am"},{"key":"R9-20260327","first-page":"133","article-title":"Role of preoperative localization and intraoperative localization maneuvers including intraoperative PTH assay determination for patients with persistent or recurrent hyperparathyroidism","volume":"17","author":"Alexander","year":"2002","journal-title":"J Bone Miner Res"}],"container-title":["Indian Journal of Endocrinology and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/02223308-201115030-00010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:58:44Z","timestamp":1786647524000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/02223308-201115030-00010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.4103\/2230-8210.83405","relation":{},"ISSN":["2230-8210","2230-9500"],"issn-type":[{"value":"2230-8210","type":"print"},{"value":"2230-9500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}