{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:04:34Z","timestamp":1793376274070,"version":"4.5.0"},"reference-count":18,"publisher":"Manuscript Technomedia LLP","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Pharma Investig"],"published-print":{"date-parts":[[2012]]},"DOI":"10.4103\/2230-973x.107007","type":"journal-article","created":{"date-parts":[[2013,2,6]],"date-time":"2013-02-06T01:36:47Z","timestamp":1360114607000},"page":"213","source":"Crossref","is-referenced-by-count":37,"title":["Evaluation of metronidazole nanofibers in patients with chronic periodontitis: A clinical study"],"prefix":"10.5530","volume":"2","author":[{"given":"PushpendraKumar","family":"Verma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ThakurPrasad","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruchi","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AnandKumar","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3478","reference":[{"key":"key-10.4103\/2230-973X.107007-1","first-page":"782","volume-title":"Mapping the pathogenesis of periodontitis: A new look","author":"Kornman","year":"1993","journal-title":"J Periodontol"},{"key":"key-10.4103\/2230-973X.107007-2","first-page":"72","volume-title":"Topical antiseptics and antibiotics in the initial therapy of chronic adult periodontitis: Microbiological aspects","author":"Quirynen","year":"2000","journal-title":"Periodontol"},{"key":"key-10.4103\/2230-973X.107007-3","unstructured":"Ahuja A, Ali J, Rahman S. Biodegradable periodontal intrapocket device containing metronidazole and amoxycillin: Formulation and characterization. Pharmazie 2006;61:25-9."},{"key":"key-10.4103\/2230-973X.107007-4","first-page":"1625","volume-title":"Pharmacokinetic principles controlling efficacy of oral therapy","author":"Goodson","year":"1989","journal-title":"J Dent Res"},{"key":"key-10.4103\/2230-973X.107007-5","first-page":"390","volume-title":"Design and evaluation of target retentive device containing metronidazole for the treatment of periodontal disease","author":"Tiwari","year":"2008","journal-title":"Res J Pharm Tech"},{"key":"key-10.4103\/2230-973X.107007-6","first-page":"390","volume-title":"Controlled release of ketoprofen from electrospun poly (vinyl alcohol) nanofibers","author":"Kenawy","year":"2007","journal-title":"Mater Sci Eng"},{"key":"key-10.4103\/2230-973X.107007-7","first-page":"2042","volume-title":"Controlled release of heparin from poly (e-caprolactone) electrospun fibers","author":"Van","year":"2006","journal-title":"Biomaterials"},{"key":"key-10.4103\/2230-973X.107007-8","first-page":"179","volume-title":"Controlled release of metronidazole benzoate from poly e-caprolactone electrospun nanofibers for periodontal diseases","author":"Zamani","year":"2010","journal-title":"Eur J Pharm Biopharm"},{"key":"key-10.4103\/2230-973X.107007-9","first-page":"43","volume-title":"Influence of the drug compatibility with polymer solution on the release kinetics of electrospun fiber formulation","author":"Zeng","year":"2005","journal-title":"J Control Release"},{"key":"key-10.4103\/2230-973X.107007-10","first-page":"33","volume-title":"Ultrafine medicated fibers electrospun from W\/O emulsions","author":"Xu","year":"2005","journal-title":"J Control Release"},{"key":"key-10.4103\/2230-973X.107007-11","first-page":"47","volume-title":"Incorporation and controlled release of a hydrophilic antibiotic using poly (lactide-co-glycolide)-based electrospun nanofibrous scaffolds","author":"Kim","year":"2004","journal-title":"J Control Release"},{"key":"key-10.4103\/2230-973X.107007-12","first-page":"169","volume-title":"Encapsulating drugs in biodegradable ultrafine fibers through co-axial electrospinning","author":"Huang","year":"2006","journal-title":"J Biomed Mater Res"},{"key":"key-10.4103\/2230-973X.107007-13","first-page":"349","volume-title":"Incorporation of drugs in an amorphous state into electrospun nanofibers composed of a water-insoluble, nonbiodegradable polymer","author":"Verreck","year":"2003","journal-title":"J Control Release"},{"key":"key-10.4103\/2230-973X.107007-14","first-page":"43","volume-title":"A comparative evaluation of atrigel delivery system (10% doxycycline hyclate) Atridox with scaling and root planing and combination therapy in treatment of periodontitis: A clinical study","author":"Javali","year":"2012","journal-title":"J Indian Soc Periodontol","ISSN":"https:\/\/id.crossref.org\/issn\/0972-124X","issn-type":"print"},{"key":"key-10.4103\/2230-973X.107007-15","first-page":"201","volume-title":"Chlorhexidine chip and tetracycline fibers as adjunct to scaling and root planing - A clinical study","author":"Srivastava","year":"2009","journal-title":"Braz J Oral Sci"},{"key":"key-10.4103\/2230-973X.107007-16","first-page":"624","volume-title":"Clinical evaluation of the use of locally delivered chlorhexidine in periodontal maintenance therapy","author":"Rodrigues","year":"2007","journal-title":"J Periodontol"},{"key":"key-10.4103\/2230-973X.107007-17","first-page":"494","volume-title":"Locally delivered antimicrobials in the management of periodontitis: A critical review of the evidence for their use in practice","author":"Hussein","year":"2007","journal-title":"Dent Update"},{"key":"key-10.4103\/2230-973X.107007-18","first-page":"365","volume-title":"Niridazole biodegradable inserts for local long-term treatment of periodontitis: Possible new life for an orphan drug","author":"Barat","year":"2006","journal-title":"Drug Deliv"}],"container-title":["International Journal of Pharmaceutical Investigation"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T09:09:50Z","timestamp":1771578590000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpionline.org\/article\/2\/4\/213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012]]}},"alternative-id":["107007"],"URL":"https:\/\/doi.org\/10.4103\/2230-973x.107007","relation":{},"ISSN":["2230-973X"],"issn-type":[{"value":"2230-973X","type":"print"}],"subject":[],"published":{"date-parts":[[2012]]}}}