{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:22:24Z","timestamp":1791490944676,"version":"4.3.4"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:p>\n                    Although in the last two decades the World Health Organization (WHO) has introduced tuberculosis as \u201ca threat to global\u201d, the vaccination with the\n                    <jats:italic toggle=\"yes\">Mycobacterium bovis<\/jats:italic>\n                    Bacillus Calmette-Guerin (BCG) is the only way for the prevention of this fatal infectious disease. Despite of the efficacy of BCG vaccine especially against infants\u2019 meningitis, it has still some limitations due to a variety of adverse effects. Many studies have evaluated the side effects of different strains of BCG vaccines in different countries. In Iran, some studies have been done so far to evaluate the adverse effects of 1173 P2 strain which is used for BCG vaccination. Each of these studies have used different standardization and sampling methods. This review will survey all studies that have been published about adverse effects of 1173 P2 strain of BCG vaccine in Iran using data mining methods.\n                  <\/jats:p>","DOI":"10.4103\/2277-9175.183659","type":"journal-article","created":{"date-parts":[[2016,6,8]],"date-time":"2016-06-08T02:48:59Z","timestamp":1465354139000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Adverse effects of BCG vaccine 1173 P2 in Iran: A meta-analysis"],"prefix":"10.4103","volume":"5","author":[{"given":"Saied","family":"Mostaan","sequence":"first","affiliation":[{"name":"Department of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahador","family":"Yazdanpanah","sequence":"additional","affiliation":[{"name":"Department of BCG, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasool","family":"Moukhah","sequence":"additional","affiliation":[{"name":"Department of BCG, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid Reza","family":"Hozouri","sequence":"additional","affiliation":[{"name":"Department of BCG, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manouchehr","family":"Rostami","sequence":"additional","affiliation":[{"name":"Department of BCG, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Khorashadizadeh","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javad","family":"Zerehsaz","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Medical School, Tarbiat Modarres University, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramin Pirhajati","family":"Mahabadi","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Medical School, Tarbiat Modarres University, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arya","family":"Saadi","sequence":"additional","affiliation":[{"name":"Technical Office, Pasteur Institute of Iran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Khanahmad","sequence":"additional","affiliation":[{"name":"Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Pooya","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2016,6,8]]},"reference":[{"key":"R1-20251008","article-title":"World Health Organization (2006). TB country profile\/Iran"},{"key":"R2-20251008","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.femsre.2005.04.013","article-title":"Mycobacterial manipulation of the hostcell","volume":"29","author":"Hestvik","year":"2005","journal-title":"FEMS Microbiol Rev"},{"key":"R3-20251008","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1183\/09031936.01.17305370","article-title":"M. tuberculosis: Immunobiology and vaccination","volume":"17","author":"Rook","year":"2001","journal-title":"Eur Respir J"},{"key":"R4-20251008","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S1473-3099(02)00182-2","article-title":"BCG\u2014different strains, different vaccines?","volume":"2","author":"Behr","year":"2002","journal-title":"Lancet Infect Dis"},{"key":"R5-20251008","first-page":"1589","article-title":"Premiers essays de vaccination antituberculeuse del\u2019enfant parle Bacille Ca;mette-Guerin(BCG)","volume":"49","author":"Weill-Halle","year":"1925","journal-title":"Bull Mem Soc Med Hosp de Paris"},{"key":"R6-20251008","first-page":"133","article-title":"Disseminated Mycobacteriumbovis iInfection after BCG vaccination","volume":"5","author":"AfsharPaiman","year":"2006","journal-title":"Iran J Allergy Asthma Immunol"},{"key":"R7-20251008","first-page":"38","article-title":"8 case report of disseminated BCG during 1998-2002 in Tehran Pediatric Center","volume":"13","author":"Karimi","year":"2003","journal-title":"Maz Uni Med Sci"},{"key":"R8-20251008","first-page":"209","article-title":"Complications of BCG vaccination in children","volume":"3","author":"Seyfhashemi","year":"2005","journal-title":"Iran J Pediatr"},{"key":"R9-20251008","first-page":"71","article-title":"Case report of BCGitis affected right muscle of abdomen","volume":"27","author":"Ghoreishi","year":"2003","journal-title":"J Isfahan Med 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Dis"},{"key":"R14-20251008","first-page":"91","volume":"12","author":"Ghadiri","year":"2007","journal-title":"Kordestan Univ Med Sci J"},{"key":"R15-20251008","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/tropej\/fmn053","article-title":"Disseminated Bacillus Calmette\u2013Guerin Infection after BCG Vaccination","volume":"54","author":"Rezai","year":"2008","journal-title":"J Trop Pediatr"},{"key":"R16-20251008","first-page":"351","article-title":"Post BCG Lymphadenitis in Vaccinated Infants in Yazd, Iran","volume":"18","author":"Behjati","year":"2008","journal-title":"I J Pediatr"},{"key":"R17-20251008","first-page":"494","article-title":"Novel RAG2 Mutation in a Patient with T\u2013 B\u2013 Severe Combined Immunodeficiency and Disseminated BCG Disease","volume":"19","author":"Sadeghi-Shabestari","year":"2009","journal-title":"J Investig Allergol Clin Immunol"},{"key":"R18-20251008","first-page":"83","article-title":"BCGiosis as a presenting feature of a child with chronic granulomatous disease","volume":"15","author":"Movahedi","year":"2011","journal-title":"Braz J Infect Dis"},{"key":"R19-20251008","first-page":"89","article-title":"Detection of Disseminated Mycobactrial Infection Due to BCG Vaccination (BCGosis) in 4 Suspected Infant Autopsies by PCR Method","volume":"2","author":"Jadali","year":"2007","journal-title":"Iran J Pathol"},{"key":"R20-20251008","first-page":"83","article-title":"Adenitis due to BCG vaccination","volume":"22","author":"Farshchian","year":"1999","journal-title":"Hakim Res J"}],"container-title":["Advanced Biomedical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01679891-201605000-00099","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:40:41Z","timestamp":1786650041000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01679891-201605000-00099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.4103\/2277-9175.183659","relation":{},"ISSN":["2277-9175"],"issn-type":[{"value":"2277-9175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"2012-03-13","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-07-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}