{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:40:10Z","timestamp":1786653610486,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"\n Background:<\/jats:title>\n The aim of this study is to determine the predictive value of ultrasonography for results of local steroid injection in patients with carpal tunnel syndrome (CTS).<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n This prospective cohort study was conducted during a 1-year period in outpatient clinics of rehabilitation and physical medicine including 35 patients with moderate and severe CTS who receive ultrasonography-guided local steroid injection. The Boston self-assessment questionnaire and electrodiagnosis parameters were recorded at baseline, 1 month, and 3 months after therapy. We also recorded the baseline ultrasonography parameters to determine the predictors of outcome.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The sensory severity score and functional status scale along with electrodiagnosis parameters decreased significantly at 1 month (\n P<\/jats:italic>\n < 0.001) and remained unchanged after 3 months. Volar bulging was negatively associated with sensory nerve action potential latency (\n r<\/jats:italic>\n = \u22120.392;\n P<\/jats:italic>\n = 0.020). Cross-sectional area (CSA) of maximal swelling (MS;\n r<\/jats:italic>\n = 0.409;\n P<\/jats:italic>\n = 0.015), CSA at 2-cm of MS (\n r<\/jats:italic>\n = 0.563;\n P<\/jats:italic>\n < 0.001), and CSA at 12-cm of MS (\n r<\/jats:italic>\n = 0.521;\n P<\/jats:italic>\n = 0.001) correlated positively with compound muscle action potential (CMAP) amplitude while maximal swelling\/12-cm MS ratio (\n r<\/jats:italic>\n = \u22120.439;\n P<\/jats:italic>\n = 0.008) and maximal swelling\/2-cm MS ratio (\n r<\/jats:italic>\n = \u22120.342;\n P<\/jats:italic>\n = 0.045) correlated negatively. CSA at 12-cm of MS also correlated positively with CMAP amplitude nerve conduction velocity (\n r<\/jats:italic>\n = 0.436;\n P<\/jats:italic>\n = 0.010).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Volar bulging, CSA of maximal swelling, CSA of MS at 2-cm, and CSA of MS at 12-cm are among the ultrasonographic predictors of response to local steroid injection in patients with CTS.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/2277-9175.225591","type":"journal-article","created":{"date-parts":[[2018,2,16]],"date-time":"2018-02-16T04:36:02Z","timestamp":1518755762000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasonography Predictive Factors of Response to Local Steroid Injection in Patients with Carpal Tunnel Syndrome"],"prefix":"10.4103","volume":"7","author":[{"given":"Farnaz","family":"Dehghan","sequence":"first","affiliation":[{"name":"From the Department of Physical Medicine and Rehabilitation, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shila","family":"Haghighat","sequence":"additional","affiliation":[{"name":"From the Department of Physical Medicine and Rehabilitation, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadiseh","family":"Ramezanian","sequence":"additional","affiliation":[{"name":"From the Department of Physical Medicine and Rehabilitation, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Karami","sequence":"additional","affiliation":[{"name":"Department of Radiology, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Reza","family":"Rezaei","sequence":"additional","affiliation":[{"name":"Department of Radiology, Isfahan University of 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