{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:34:41Z","timestamp":1787758481716,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Descending necrotizing mediastinitis (DNM) is one of the most critical, and often lethal forms of mediastinitis that develop because of the downward spread of deep neck infections. In this article, we wanted to discuss a case report with DNM secondary to retropharyngeal abscess detected in the emergency department, in accordance with the literature. A 51-year-old male patient presented to the hospital with complaints of fever, sore throat when swallowing, and swelling in the neck. He had no history of any disease, trauma, or surgical intervention. On physical examination of our patient, diffuse hyperemia and edema in the pharyngeal area were detected with swelling, edema, redness, and warmth in the neck, which can be felt on both sides of the trachea with palpation. DNM diagnosis was made by detecting retropharyngeal abscess extending to the mediastinum, mediastinal air images and increased density in adipose tissue with intravenous (IV) contrast-enhanced neck and thorax computed tomography (CT). DNM patients most frequently present with complaints of fever, odynophagia, dyspnea, cervical edema, and pain. The most important clinical finding is edema and hyperemia in the pharynx. Our patient presented to the emergency department with complaints of fever, sore throat when swallowing, and neck swelling, and on physical examination, edema, hyperemia, and temperature increase in the neck region were observed together with hyperemia and edema in the pharyngeal area. Laboratory examinations showed high leukocyte count and C-reactive protein levels. The patient was diagnosed with DNM by performing IV contrast-enhanced cervicothoracic CT imaging and underwent an operation. It should be borne in mind that patients who present to the emergency room with fever, odynophagia, and neck swelling may have a rare but seriously life-threatening DNM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/2452-2473.357345","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T14:29:35Z","timestamp":1664461775000},"page":"230-232","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A rare case"],"prefix":"10.4103","volume":"22","author":[{"given":"Bar\u0131\u015f Murat","family":"Ayvaci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eren","family":"G\u00f6kda\u011f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20240909","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/S0003-4975(03)01333-X","article-title":"Descending necrotizing mediastinitis: A minimally invasive approach using video-assisted thoracoscopic surgery","volume":"77","author":"Min","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"R2-10-20240909","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1097\/00005537-200404000-00035","article-title":"Management of descending necrotizing mediastinitis","volume":"114","author":"Makeieff","year":"2004","journal-title":"Laryngoscope"},{"key":"R3-10-20240909","first-page":"291","article-title":"Surgical treatment of descending necrotising mediastinitis caused by odontogenic infection: A retrospective analysis of 20 patients","volume":"123","author":"Lucenic","year":"2022","journal-title":"Bratisl Lek Listy"},{"key":"R4-10-20240909","doi-asserted-by":"crossref","first-page":"e66","DOI":"10.1093\/ejcts\/ezs385","article-title":"Diffuse descending necrotizing mediastinitis: Surgical therapy and outcome in a single-centre series","volume":"42","author":"Kocher","year":"2012","journal-title":"Eur J Cardiothorac Surg"},{"key":"R5-10-20240909","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1086\/596015","article-title":"Incidence of and preoperative risk factors for Staphylococcus aureus bacteremia and chest wound infection after cardiac surgery","volume":"30","author":"Kanafani","year":"2009","journal-title":"Infect Control Hosp Epidemiol"},{"key":"R6-10-20240909","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s00405-006-0174-z","article-title":"Descending necrotising mediastinitis: A safe treatment algorithm","volume":"264","author":"De Freitas","year":"2007","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"R7-10-20240909","first-page":"545","article-title":"Descending necrotizing mediastinitis","volume":"157","author":"Estrera","year":"1983","journal-title":"Surg Gynecol Obstet"},{"key":"R8-10-20240909","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/0003-4975(90)90022-X","article-title":"Descending necrotizing mediastinitis: Transcervical drainage is not enough","volume":"49","author":"Wheatley","year":"1990","journal-title":"Ann Thorac Surg"},{"key":"R9-10-20240909","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/s11908-011-0174-z","article-title":"Update on necrotizing mediastinitis: Causes, approaches to management, and outcomes","volume":"13","author":"Sandner","year":"2011","journal-title":"Curr Infect Dis Rep"},{"key":"R10-10-20240909","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.joms.2003.08.039","article-title":"Management of descending necrotizing mediastinitis","volume":"62","author":"Mihos","year":"2004","journal-title":"J Oral Maxillofac Surg"},{"key":"R11-10-20240909","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S1808-8694(15)31097-1","article-title":"Deep neck infection: Analysis of 80 cases","volume":"74","author":"Suehara","year":"2008","journal-title":"Braz J Otorhinolaryngol"}],"container-title":["Turkish Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/2452-2473.357345","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:15:54Z","timestamp":1787757354000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/2452-2473.357345"}},"subtitle":["Descending necrotizing mediastinitis"],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/2452-2473.357345","relation":{},"ISSN":["2452-2473"],"issn-type":[{"value":"2452-2473","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}