{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:32:22Z","timestamp":1787776342050,"version":"build-2784847793"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>Malignant peripheral nerve sheath tumor (MPNST) contains properties and histologic markers of both neural crest cells and mesenchymal cells. It is a rare diagnosis, with an incidence of 1:100,000\/year or 4%\u201310% of soft-tissue sarcomas. There are very few cases reported and studied. Therefore, establishing a proper diagnosis and treatment of MPNST provides a challenge. We present this unique and rare case of metastatic MPNST of the small and large bowel with bone, pulmonary, liver, and splenic metastases. The patient subsequently developed hemorrhagic brain metastases and died 6 months after THE initial diagnosis.<\/jats:p>","DOI":"10.4103\/aam.aam_10_20","type":"journal-article","created":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T16:14:12Z","timestamp":1725120852000},"page":"228-231","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["A Rare Case Report of Malignant Peripheral Nerve Sheath Tumor Involving Both the Small Bowel and Large Bowel"],"prefix":"10.4103","volume":"20","author":[{"given":"Nazia","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, St. Michael's Medical Center, Newark, NJ, an Affiliate of New York Medical College, Westchester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irma","family":"Hashmi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, St. Michael's Medical Center, Newark, NJ, an Affiliate of New York Medical College, Westchester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liana","family":"Atallah","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, St. Michael's Medical Center, Newark, NJ, an Affiliate of New York Medical College, Westchester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Shaaban","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, St. Michael's Medical Center, Newark, NJ, an Affiliate of New York Medical College, Westchester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunwant","family":"Guron","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, St. Michael's Medical Center, Newark, NJ, an Affiliate of New York Medical College, Westchester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Fedida","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, St. Michael's Medical Center, Newark, NJ, an Affiliate of New York Medical College, Westchester, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,9,17]]},"reference":[{"key":"R1-20250528","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.4103\/jomfp.JOMFP_9_20","article-title":"Malignant peripheral nerve sheath tumor: A rare malignancy","volume":"24","author":"Sharma","year":"2020","journal-title":"J Oral Maxillofac Pathol"},{"key":"R2-20250528","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1007\/s11605-007-0395-5","article-title":"Malignant peripheral nerve sheath tumor: An unusual cause of intussusception","volume":"12","author":"Telem","year":"2008","journal-title":"J Gastrointest Surg"},{"key":"R3-20250528","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.ciresp.2010.03.037","article-title":"Tumor maligno de la vaina de los nervios perif\u00e9ricos en el intestino Delgado","volume":"89","author":"Mart\u00edn","year":"2011","journal-title":"Cir Esp"},{"key":"R4-20250528","doi-asserted-by":"crossref","first-page":"245","DOI":"10.2169\/internalmedicine.55.5456","article-title":"Malignant peripheral nerve sheath tumor of the liver","volume":"55","author":"Kakizaki","year":"2016","journal-title":"Intern Med"},{"key":"R5-20250528","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3892\/mco.2015.703","article-title":"Primary peripheral nerve sheath tumors of the thyroid gland: A case report and literature review","volume":"4","author":"Chen","year":"2016","journal-title":"Mol Clin Oncol"},{"key":"R6-20250528","first-page":"72","article-title":"Malignant peripheral nerve sheath tumor in three patients of advanced age","volume":"14","author":"Wruhs","year":"2016","journal-title":"J Dtsch Dermatol Ges"},{"key":"R7-20250528","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.3171\/2015.7.JNS151056","article-title":"Malignant peripheral nerve sheath tumors of the eighth cranial nerve arising without prior irradiation","volume":"125","author":"Carlson","year":"2016","journal-title":"J Neurosurg"},{"key":"R8-20250528","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1002\/1097-0142(19860515)57:10<2006::AID-CNCR2820571022>3.0.CO;2-6","article-title":"Malignant peripheral nerve sheath tumors. 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