{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:27:20Z","timestamp":1790476040599,"version":"4.1.0"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    Endogenous endophthalmitis is an intraocular inflammation caused by the hematogenous spread of microorganisms from distant foci.\n                    <jats:italic toggle=\"yes\">Streptococcus mitis<\/jats:italic>\n                    is a low-virulence organism that inhabits the oral cavity; however, it has rarely been reported to cause endogenous endophthalmitis. In this case report, we present a 63-year-old woman with bilateral asymmetrical endogenous endophthalmitis and a severely affected right eye, with light perception vision, hypotony, and severe anterior and posterior segment inflammation. The left eye exhibited intraretinal infectious infiltrates and minimal vitritis. However, the cause of the\n                    <jats:italic toggle=\"yes\">S. mitis<\/jats:italic>\n                    bacteremia was unclear. Considering the patient\u2019s recent dental implant procedure, we hypothesized that the bacteria may have entered the bloodstream through the oral cavity. The patient received intravitreal and systemic antibiotics and underwent pars plana vitrectomy for the right eye. In conclusion, we present a case of endogenous endophthalmitis, presumed following a dental implant procedure.\n                    <jats:italic toggle=\"yes\">S. mitis<\/jats:italic>\n                    may invade the bloodstream following an uncomplicated dental procedure, leading to bilateral endogenous endophthalmitis. Early detection, prompt management with systemic and intravitreal antibiotics, and early vitrectomy may potentially preserve the patient\u2019s globe and vision.\n                  <\/jats:p>","DOI":"10.4103\/aam.aam_121_24","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T07:04:07Z","timestamp":1731049447000},"page":"202-205","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Bilateral Endogenous Streptococcus mitis Endophthalmitis Following Dental Implant: A Case Report and Literature Review"],"prefix":"10.4103","volume":"24","author":[{"given":"Asma","family":"Alzuabi","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saleh","family":"Alrashed","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad","family":"Aldahmash","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"key":"R1-20260427","first-page":"144","article-title":"The clinical analysis of endogenous endophthalmitis","volume":"20","author":"Liang","year":"2004","journal-title":"Yan Ke Xue Bao"},{"key":"R2-20260427","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/IIO.0b013e31803778f7","article-title":"Endogenous bacterial and fungal endophthalmitis","volume":"47","author":"Smith","year":"2007","journal-title":"Int Ophthalmol Clin"},{"key":"R3-20260427","doi-asserted-by":"crossref","first-page":"e0151908.","DOI":"10.1371\/journal.pone.0151908","article-title":"StreptoBase: An oral Streptococcus mitis group genomic resource and analysis platform","volume":"11","author":"Zheng","year":"2016","journal-title":"PLoS One"},{"key":"R4-20260427","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.ajo.2011.11.035","article-title":"An outbreak of Streptococcus endophthalmitis after intravitreal injection of bevacizumab","volume":"153","author":"Goldberg","year":"2012","journal-title":"Am J Ophthalmol"},{"key":"R5-20260427","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.2147\/TCRM.S149094","article-title":"Successful management of late-onset Streptococcus mitis endophthalmitis","volume":"13","author":"Chon","year":"2017","journal-title":"Ther Clin Risk Manag"},{"key":"R6-20260427","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S0002-9394(14)71048-7","article-title":"Endogenous endophthalmitis caused by Streptococcus mitis","volume":"123","author":"Harrison","year":"1997","journal-title":"Am J Ophthalmol"},{"key":"R7-20260427","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1099\/jmm.0.012658-0","article-title":"Levofloxacin-resistant-Streptococcus mitis endophthalmitis: a unique presentation of bacterial endocarditis","volume":"58","author":"Dinani","year":"2009","journal-title":"J Med Microbiol"},{"key":"R8-20260427","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3109\/00365548.2012.703786","article-title":"A case of endogenous endophthalmitis complicated by neutropenia following bacteremia with Streptococcus mitis resistant to beta-lactam antibiotics","volume":"45","author":"Ono","year":"2013","journal-title":"Scand J Infect Dis"},{"key":"R9-20260427","doi-asserted-by":"crossref","first-page":"e239187.","DOI":"10.1136\/bcr-2020-239187","article-title":"Endogenous Streptococcus mitis panophthalmitis in a patient visiting the Dominican Republic","volume":"14","author":"Liu","year":"2021","journal-title":"BMJ Case Rep"},{"key":"R10-20260427","first-page":"1190","article-title":"A case of endogenous Streptococcus mitis endophthalmitis in a patient with Staphylococcus aureus sepsis","volume":"53","author":"Lee","year":"2012","journal-title":"JKOS"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_121_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:52:51Z","timestamp":1786647171000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_121_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,8]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_121_24","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,8]]},"assertion":[{"value":"2024-07-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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