{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:29:42Z","timestamp":1786728582754,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>Mitral valve aneurysm is defined as outpouching of the mitral valve which expands in systole and collapse in diastole. It was first reported in 1729 by Morand. Most of the cases have been described in the African population. It is rare in the Indian population. Its chief presentations are congestive heart failure, palpitations, arrhythmia, or in rare cases an embolic phenomenon. It can be diagnosed either by echocardiography or cardiac imaging (magnetic resonance imaging\/computed tomography). It can either occur as an isolated defect or with other associated valvular abnormalities. Here, we present a case of a 40-year-old male who was referred for the evaluation of palpitation who on the investigation was found to have a bicuspid aortic valve with severe Aortic Regurgitation (AR) along with aneurysm in the anterior mitral leaflet causing severe mitral regurgitation. This case highlights the importance of keeping a submitral aneurysm as a differential diagnosis for mitral regurgitation and searching for other associated valvular defects which may affect the management and treatment outcomes.<\/jats:p>","DOI":"10.4103\/aam.aam_142_22","type":"journal-article","created":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T02:06:24Z","timestamp":1689818784000},"page":"554-556","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Rare Association of Aneurysm of Anterior Mitral Leaflet with Bicuspid Aortic Valve"],"prefix":"10.4103","volume":"22","author":[{"given":"Vivek","family":"Mohanty","sequence":"first","affiliation":[{"name":"Department of Cardiology, All India Institute of Medical Science, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubham Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Cardiology, All India Institute of Medical Science, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surender","family":"Deora","sequence":"additional","affiliation":[{"name":"Department of Cardiology, All India Institute of Medical Science, Jodhpur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,7,20]]},"reference":[{"key":"R1-20260512","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/hrt.22.2.181","article-title":"Left ventricular aneurysm in the African","volume":"22","author":"Lurie","year":"1960","journal-title":"Br Heart J"},{"key":"R2-20260512","first-page":"153","article-title":"Profile of submitral left ventricular aneurysms in Indian patients","volume":"42","author":"Sharma","year":"1990","journal-title":"Indian Heart J"},{"key":"R3-20260512","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1161\/01.CIR.32.1.43","article-title":"Annular subvalvular left ventricular aneurysms in the South African Bantu","volume":"32","author":"Chesler","year":"1965","journal-title":"Circulation"},{"key":"R4-20260512","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/0003-4975(95)00099-7","article-title":"Surgical management of ventricular tachycardia in subannular left ventricular aneurysm","volume":"60","author":"Janeira","year":"1995","journal-title":"Ann Thorac Surg"},{"key":"R5-20260512","first-page":"476","article-title":"Review: Mitral valve aneurysms in infective endocarditis: Mechanisms, clinical recognition, and treatment","volume":"18","author":"Silbiger","year":"2009","journal-title":"J Heart Valve Dis"},{"key":"R6-20260512","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0002-9149(99)00206-4","article-title":"Clinical, anatomic, and echocardiographic characteristics of aneurysms of the mitral valve","volume":"84","author":"Vilacosta","year":"1999","journal-title":"Am J Cardiol"},{"key":"R7-20260512","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0002-9149(70)90761-7","article-title":"The congenitally bicuspid aortic valve. A study of 85 autopsy cases","volume":"26","author":"Roberts","year":"1970","journal-title":"Am J Cardiol"},{"key":"R8-20260512","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/eurheartj\/ehn322","article-title":"Sub-mitral aneurysm","volume":"30","author":"Guimfacq","year":"2009","journal-title":"Eur Heart J"},{"key":"R9-20260512","first-page":"140","article-title":"Distorted posterior mitral leaflet mimicking a mass in the left atrium \u2013 A rare presentation of submitral aneurysm","volume":"2","author":"Bashi","year":"2018","journal-title":"IHJ Cardiovasc Case Rep (CVCR)"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_142_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:28:54Z","timestamp":1786724934000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_142_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,20]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_142_22","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,20]]},"assertion":[{"value":"2022-10-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}