{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:32:24Z","timestamp":1786649544653,"version":"build-2736575974"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T00:00:00Z","timestamp":1734739200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The stressful life of medical students might induce or exacerbate irritable bowel syndrome (IBS) symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The purpose of this study was to determine the prevalence and related factors of IBS among medical students at King Khalid University (KKU), Saudi Arabia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A descriptive cross-sectional study was conducted among medical students at the KKU. The data collection period was from January to February 2018. Stratified sampling technique was used that included medical students from the second to the sixth year, using self-administered questionnaires contain socio-demographics, medical history, Rome criteria IV, and a personality scale of manifest anxiety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The intended participants were 400 medical students (100%) with 363 (90%) respondents. The mean age was 22 \u00b1 1.6 years; there were 52.9% males and 47.1% females. The prevalence rate of IBS according to the Rome IV criteria was 10.7%. Regarding diagnostic criteria for IBS subtypes, 23.1% represented for both IBS with predominant constipation and IBS with predominant diarrhea, IBS with mixed bowel habits, both diarrhea and constipation, are the higher percentage (43.6%), and IBS unclassified subtype represented by 10.3%. Chi-square test showed high correlation between age and smoking and body mass index (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.04 and 0.05, respectively). Further, there is a significant relationship between IBS and anxiety level (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.04). No gender difference was noted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The prevalence of IBS among medical students at KKU was highest in the age group of 21\u201323 years, who were nonsmokers, and who had a relatively high grade point average. We did not find a gender difference. Compared to non-IBS students, the anxiety level of the students with IBS was dramatically higher.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_14_19","type":"journal-article","created":{"date-parts":[[2024,12,22]],"date-time":"2024-12-22T23:00:08Z","timestamp":1734908408000},"page":"173-178","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence and Associated Factors of Irritable Bowel Syndrome among Medical Students at King Khalid University"],"prefix":"10.4103","volume":"24","author":[{"given":"Turki Khalid","family":"Alshehri","sequence":"first","affiliation":[{"name":"College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Nasser Saeed","family":"Alsharif","sequence":"additional","affiliation":[{"name":"College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lujain Ahmed Ali","family":"Asiri","sequence":"additional","affiliation":[{"name":"College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Saeed","family":"Mukharrib","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, King Abdullah Hospital, Bisha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Attieh","family":"Alzahrani","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,21]]},"reference":[{"key":"R1-20260427","doi-asserted-by":"crossref","first-page":"6031","DOI":"10.3748\/wjg.v20.i20.6031","article-title":"Role of antispasmodics in the treatment of irritable bowel syndrome","volume":"20","author":"Annah\u00e1zi","year":"2014","journal-title":"World J Gastroenterol"},{"key":"R2-20260427","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s00384-012-1598-0","article-title":"IBS and the role of otilonium bromide","volume":"28","author":"Boeckxstaens","year":"2013","journal-title":"Int J Colorectal Dis"},{"key":"R3-20260427","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/00004836-199912000-00009","article-title":"A national survey of practice patterns of gastroenterologists with comparison to the past two decades","volume":"29","author":"Russo","year":"1999","journal-title":"J Clin Gastroenterol"},{"key":"R4-20260427","doi-asserted-by":"crossref","first-page":"G775","DOI":"10.1152\/ajpgi.00155.2012","article-title":"Irritable bowel syndrome: Methods, mechanisms, and pathophysiology. 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