{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:20:00Z","timestamp":1787840400747,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Obstructive sleep apnea (OSA) is characterized by repeated episodes of upper airway obstruction during sleep, resulting in fragmented sleep and associated health risks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This retrospective study investigated the clinical and polysomnographic differences between obese and nonobese patients diagnosed with OSA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>A total of 210 patients underwent a Level 3 sleep study. Based on the apnea-hypopnea index (AHI), 180 patients with OSA were included in the study. Patients were categorized as obese (body mass index [BMI] \u226527.5) or nonobese (BMI &lt;27.5). Clinical parameters, AHI, oxygen desaturation index (ODI), Epworth Sleepiness Scale (ESS), neck circumference, age, and gender were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Obese patients had significantly higher AHI, ODI, ESS scores, and neck circumference than nonobese patients (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Gender was associated with the severity of OSA only in the obese group. Age was not significantly associated with OSA severity in either group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Obesity is strongly associated with more severe OSA and anatomical risk factors. Nonobese OSA patients also exhibited clinically relevant symptoms, suggesting distinct nonanatomical mechanisms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study concludes that while obesity is linked to more severe OSA due to anatomical factors, non-obese patients also experience significant disease, highlighting the importance of individualized, phenotype-driven management strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_151_25","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T09:00:21Z","timestamp":1755680421000},"page":"629-633","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Clinical and Polysomnographic Differences in Obese and Nonobese Patients with Obstructive Sleep Apnea"],"prefix":"10.4103","volume":"25","author":[{"given":"Supriya","family":"Adiody","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Jubilee Mission Medical College and Research Institute, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Vishnu","family":"Narayanan","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Jubilee Mission Medical College and Research Institute, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"R1-20260504","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S2213-2600(19)30198-5","article-title":"Estimation of the global prevalence and burden of obstructive sleep apnoea: A literature-based analysis","volume":"7","author":"Benjafield","year":"2019","journal-title":"Lancet Respir Med"},{"key":"R2-20260504","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1001\/jama.291.16.2013","article-title":"Risk factors for OSA in adults","volume":"291","author":"Young","year":"2004","journal-title":"JAMA"},{"key":"R3-20260504","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1513\/pats.200709-155MG","article-title":"The epidemiology of adult obstructive sleep apnea","volume":"5","author":"Punjabi","year":"2008","journal-title":"Proc Am Thorac Soc"},{"key":"R4-20260504","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1164\/rccm.201303-0448OC","article-title":"Defining phenotypic causes of obstructive sleep apnea. 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