{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:41:22Z","timestamp":1787071282323,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cervical schwannomas are rare benign tumors that can present a significant diagnostic challenge, particularly when they exhibit cystic changes that mimic more common lesions such as second-branchial cleft cysts. We report the case of a 36-year-old male who presented with a gradually enlarging, firm, nontender neck mass. Imaging studies, including ultrasound and contrast-enhanced computed tomography, suggested a cystic lesion, most likely a second branchial cleft cyst. Fine-needle aspiration cytology was inconclusive. Surgical excision was undertaken, and histopathological examination revealed a schwannoma with areas of cystic degeneration. Immunohistochemistry demonstrated strong diffuse positivity for S100 protein, confirming the diagnosis. Postoperatively, the patient had an uneventful recovery without neurological deficits. This case highlights the importance of considering cervical schwannoma in the differential diagnosis of cystic neck masses and underscores the essential role of histopathology and immunohistochemistry in establishing an accurate diagnosis. Early recognition and complete surgical excision are key to achieving favorable outcomes.<\/jats:p>","DOI":"10.4103\/aam.aam_156_25","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T11:00:24Z","timestamp":1763636424000},"page":"958-961","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Cervical Schwannoma: A Rare Case Presentation \u2013 Neural Tissue Tumour"],"prefix":"10.4103","volume":"25","author":[{"given":"Prabhat Bhaskarrao","family":"Nichkaode","sequence":"first","affiliation":[{"name":"Department of General Surgery, Dr. D. Y. Patil Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raghav","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Dr. D. Y. Patil Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"key":"R2-20260803","doi-asserted-by":"crossref","first-page":"5355","DOI":"10.4081\/rt.2014.5355","article-title":"A case of cystic schwannoma in the neck masquerading as branchial cleft cyst","volume":"6","author":"Bohara","year":"2014","journal-title":"Rare Tumors"},{"key":"R3-20260803","doi-asserted-by":"crossref","first-page":"e6560","DOI":"10.1002\/ccr3.6560","article-title":"Cervical vagal schwannoma, a rare differential of a neck swelling: A case report","volume":"10","author":"Prajapati","year":"2022","journal-title":"Clin Case Rep"},{"key":"R4-20260803","doi-asserted-by":"crossref","first-page":"45","DOI":"10.18203\/issn.2454-5929.ijohns20150588","article-title":"Cystic schwannoma of cervical sympathetic chain masquerading as type II second branchial cleft cyst","volume":"1","author":"Bihani","year":"2015","journal-title":"Int J Otorhinolaryngol Head Neck Surg"},{"key":"R5-20260803","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.ijscr.2017.10.065","article-title":"Unusually rapid development of a lateral neck mass: Diagnosis and treatment of a branchial cleft cyst. A case report","volume":"41","author":"Bocchialini","year":"2017","journal-title":"Int J Surg Case Rep"},{"key":"R6-20260803","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1007\/s12663-022-01691-9","article-title":"Extracranial head and neck schwannomas: A case series and review of literature","volume":"21","author":"Madhulaxmi","year":"2022","journal-title":"J Maxillofac Oral Surg"},{"key":"R7-20260803","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s00405-008-0678-9","article-title":"Cystic schwannoma of the cervical plexus masquerading as a type II second branchial cleft cyst","volume":"266","author":"Buchanan","year":"2009","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"R8-20260803","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1148\/radiology.152.3.6463255","article-title":"Branchial cleft anomalies and their mimics: Computed tomographic evaluation","volume":"152","author":"Harnsberger","year":"1984","journal-title":"Radiology"},{"key":"R9-20260803","doi-asserted-by":"crossref","first-page":"98","DOI":"10.4103\/0975-2870.148866","article-title":"Cystic schwannoma mimicking a second branchial cleft cyst on computed tomography","volume":"8","author":"Gupta","year":"2015","journal-title":"Med J D Patil Univ"},{"key":"R10-20260803","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1002\/hed.25520","article-title":"Fine-needle aspiration cytology versus core-needle biopsy for the diagnosis of extracranial head and neck schwannoma","volume":"40","author":"Ahn","year":"2018","journal-title":"Head Neck"},{"key":"R11-20260803","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.3390\/medicina59061013","article-title":"Diagnostic and therapeutic strategy for vagal schwannoma: Case series and literature review","volume":"59","author":"Loperfido","year":"2023","journal-title":"Medicina (Kaunas)"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_156_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:44:06Z","timestamp":1787067846000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_156_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,20]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_156_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,20]]},"assertion":[{"value":"2025-05-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-10","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}