{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:47:07Z","timestamp":1787071627819,"version":"build-2736575974"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Intrauterine insemination (IUI) is a popular method for the treatment of infertility, however, its success rate ranges from 7 to 13% in a cycle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The present study was carried out to assess the IUI success rate and its predictors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>A prospective observational study was conducted, and 167 women (aged 21-49 years) with primary or secondary infertility were enrolled to undergo intrauterine insemination. The induction of ovulation for IUI was performed according to the standard protocols. Stimulation was done with letrozole\/clomiphene\/ FSH\/HMG or a combination of these drugs. Human Chorionic Gonadotropin (hCG) was administered at achievement of follicular size 17-18 mm. IUI was done 36\u201340 hours after the hCG trigger. The luteal phase was supplemented wherever needed. A positive urine pregnancy test (UPT) done 2 weeks after IUI was considered as the primary outcome. Predictors of UPT success were evaluated using Chi-square and Independent Samples t-tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean age of women was 30.58\u00b1(SD)4.43 years. The mean duration of infertility was 4\u00b12.65 years. Majority (77.6%) had primary infertility. UPT positivity rate was 18.2% in &lt;30 years and 21.3% in 30 to 45 years and no positive pregnancy in &gt; 45 years. No significant association of age, BMI, level of physical activity, fertility type, ovulation induction frequency, AMH, sperm count, and HSG was seen with outcome (p&gt;0.05). A significant association of outcome with endometrial thickness was observed( p-value 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The IUI success rate was 18.8%. The endometrial thickness was significant predictors of IUI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_176_24","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T15:02:59Z","timestamp":1760022179000},"page":"16-21","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Pregnancy Rate in Intrauterine Insemination and Associated Prognostic Factors"],"prefix":"10.4103","volume":"25","author":[{"given":"Apoorwa","family":"Sharma","sequence":"first","affiliation":[{"name":"Junior Resident, Department of Obstetrics and Gynaecology, BVMC, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suchita","family":"Dabhadkar","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Obstetrics and Gynaecology, BVMC, Pune, Maharashtra, 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