{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:20:00Z","timestamp":1787840400793,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Kikuchi-Fujimoto disease (KFD), or histiocytic necrotizing lymphadenitis, is a rare, benign, and self-limiting condition that typically affects young women and is uncommon in children or males. We report the case of a 15-year-old boy who presented with generalized lymphadenopathy involving cervical, axillary, submandibular, and inguinal nodes, along with mild fever and pain. A series of fine-needle aspiration cytology and lymph node biopsies over 3 years initially showed reactive and acute lymphadenitis. The diagnosis of Kikuchi\u2019s disease was eventually confirmed on histopathology of an axillary lymph node, which revealed necrotizing lymphadenitis without granulomas. The patient improved with symptomatic treatment using nonsteroidal anti-inflammatory drugs and antibiotics. This case highlights the diagnostic challenges of KFD in an atypical demographic and underlines the importance of repeated histopathological assessment in persistent or recurrent lymphadenopathy.<\/jats:p>","DOI":"10.4103\/aam.aam_218_25","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T09:00:09Z","timestamp":1755680409000},"page":"703-705","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Generalized Lymphadenopathy in a Young Boy: A Rare Presentation of Kikuchi-Fujimoto Disease"],"prefix":"10.4103","volume":"25","author":[{"given":"Anand Nandkumar","family":"Dugad","sequence":"first","affiliation":[{"name":"Department of General Medicine, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek Hitesh","family":"Lapsiwala","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"R1-20260504","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s12262-015-1231-x","article-title":"Kikuchi's disease: A diagnostic dilemma","volume":"77","author":"Pai","year":"2015","journal-title":"Indian J Surg"},{"key":"R2-20260504","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/s12105-019-01026-0","article-title":"Kikuchi-Fujimoto disease and prognostic implications","volume":"14","author":"Salamat","year":"2020","journal-title":"Head Neck Pathol"},{"key":"R3-20260504","first-page":"329","article-title":"Kikuchi's histiocytic necrotizing lymphadenitis: An analysis of 108 cases with emphasis on differential diagnosis","volume":"5","author":"Dorfman","year":"1988","journal-title":"Semin Diagn Pathol"},{"key":"R4-20260504","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s10067-006-0230-5","article-title":"Kikuchi-Fujimoto disease: Analysis of 244 cases","volume":"26","author":"Kucukardali","year":"2007","journal-title":"Clin Rheumatol"},{"key":"R5-20260504","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1309\/YF081L4TKYWVYVPQ","article-title":"Enigmatic Kikuchi-Fujimoto disease: A comprehensive review","volume":"122","author":"Bosch","year":"2004","journal-title":"Am J Clin Pathol"},{"key":"R6-20260504","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4103\/0970-9371.54870","article-title":"Fine-needle aspiration cytology of Kikuchi Fujimoto disease","volume":"26","author":"Hasan","year":"2009","journal-title":"J Cytol"},{"key":"R7-20260504","doi-asserted-by":"crossref","DOI":"10.1136\/bcr.11.2009.2469","article-title":"Recurrent Kikuchi-Fujimoto disease","author":"Spooner","year":"2010","journal-title":"BMJ Case Rep 2010"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_218_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:22:03Z","timestamp":1787836923000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_218_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,20]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_218_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,20]]},"assertion":[{"value":"2025-06-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-30","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}