{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:18:10Z","timestamp":1787840290568,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T00:00:00Z","timestamp":1741651200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Susac syndrome is a rare microangiopathy affecting the brain, retina, and cochlea. Individuals affected typically present with a classical clinical triad of branch retinal artery occlusion (BRAO), encephalopathy or white matter lesions, and sensorineural hearing loss. Herein, we report an exceedingly rare case of a middle-aged female patient with multiple presentations related to her visual field complaints. The presence of multiple bilateral BRAOs, in addition to sensorineural hearing impairment and white matter lesions on the brain magnetic resonance imaging, led to the diagnosis of Susac syndrome. Cases of Susac syndrome are few and far between and have seldom been reported in detail. Awareness of this rare presentation by clinicians and radiologists is of utmost importance to aid in correctly diagnosing and treating such patients.<\/jats:p>","DOI":"10.4103\/aam.aam_234_24","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T01:04:33Z","timestamp":1741741473000},"page":"496-500","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Susac Syndrome with Classical Triad: A Case Report and Literature Review"],"prefix":"10.4103","volume":"24","author":[{"given":"Bashair","family":"Alshehri","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amaar","family":"Amir","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Razan","family":"Alshehri","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hissah","family":"Alturki","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dhahran Eye Specialist Hospital, Dhahran, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talal","family":"Aljudi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dhahran Eye Specialist Hospital, Dhahran, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Alzuabi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,11]]},"reference":[{"key":"R1-20260423","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1136\/jnnp-2016-314295","article-title":"Diagnostic criteria for Susac syndrome","volume":"87","author":"Kleffner","year":"2016","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R2-20260423","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1212\/WNL.29.3.313","article-title":"Microangiopathy of the brain and retina","volume":"29","author":"Susac","year":"1979","journal-title":"Neurology"},{"key":"R3-20260423","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nrneurol.2013.82","article-title":"Characteristics of Susac syndrome: A review of all reported cases","volume":"9","author":"D\u00f6rr","year":"2013","journal-title":"Nat Rev Neurol"},{"key":"R4-20260423","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.jns.2007.01.036","article-title":"Susac\u2019s syndrome: 1975\u20132005 microangiopathy\/autoimmune endotheliopathy","volume":"257","author":"Susac","year":"2007","journal-title":"J Neurol Sci"},{"key":"R5-20260423","doi-asserted-by":"crossref","first-page":"46.","DOI":"10.1186\/1742-2094-11-46","article-title":"Clinical, paraclinical and serological findings in Susac syndrome: An international multicenter study","volume":"11","author":"Jarius","year":"2014","journal-title":"J Neuroinflammation"},{"key":"R6-20260423","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.autrev.2014.04.004","article-title":"Susac\u2019s syndrome \u2013 Pathogenesis, clinical variants and treatment approaches","volume":"13","author":"Greco","year":"2014","journal-title":"Autoimmun Rev"},{"key":"R7-20260423","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1177\/1747493017751737","article-title":"Guidelines for treatment of Susac syndrome \u2013 An update","volume":"15","author":"Rennebohm","year":"2020","journal-title":"Int J Stroke"},{"key":"R8-20260423","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1093\/brain\/awab476","article-title":"Susac syndrome: Challenges in the diagnosis and treatment","volume":"145","author":"Marrodan","year":"2022","journal-title":"Brain"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_234_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:19:35Z","timestamp":1787836775000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_234_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,11]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_234_24","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,11]]},"assertion":[{"value":"2024-11-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-24","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}