{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:56:51Z","timestamp":1791219411784,"version":"4.1.0"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The burden, profile, and outcomes of pediatric human immunodeficiency virus (HIV) have not been exhaustively studied in developing countries. The present study hopes to fill some of this knowledge gap.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The study aimed to document the burden and profile of pediatric HIV admission at Wesley Guild Hospital, Ilesa, Nigeria, with emphasis on highlighting peculiarities in our setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective study of the case records of all HIV-infected children admitted and managed on the pediatric infectious ward over 15 years. Data obtained from the information were analyzed using SPSS version 20, and inferences were made.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The total HIV-infected children population studied consisted of 18 (47.4%) boys and 20 (52.6%) girls with a mean age of 4.06 \u00b1 3.90 years. Transmission of HIV was vertical in all, while diagnosis of HIV infection was made during the index admission in 35 (92.1%). Tuberculosis, community-acquired pneumonia, severe malaria,\n                      <jats:italic toggle=\"yes\">Pneumocystis<\/jats:italic>\n                      pneumonia, sepsis, and cryptococcal infections accounted for more than 80% of admissions. Severe malaria was more common in the above 5 years of age group. Candida and scabies were the most common coinfections and infestations, respectively. More than 50% of admissions were complicated with anemia and hypoxemia. The nine recorded deaths represent 23.7% of the population studied, with\n                      <jats:italic toggle=\"yes\">Pneumocystis<\/jats:italic>\n                      pneumonia and cryptococcal infections accounting for more than half of the deaths. Hypoxemia and acquired immunodeficiency syndrome were significantly associated with death (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Childhood HIV infections are a significant contributor to pediatric infectious morbidity, with high HIV case mortality rates. Strategies to reverse this narrative are urgently needed for deployment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_259_25","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T16:00:45Z","timestamp":1764086445000},"page":"1739-1744","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Pediatric Human Immunodeficiency Virus Infections Admissions and Outcome at Wesley Guild Hospital, Ilesa, Nigeria"],"prefix":"10.4103","volume":"25","author":[{"given":"Olusola Adetunji","family":"Oyedeji","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Wesley Guild Hospital, Unit of Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virtue Tomisona","family":"Olaitan","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Obafemi Awolowo 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