{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:26:23Z","timestamp":1787761583634,"version":"build-2784847793"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Hypertensive disorders in pregnancy are among the most serious complications of pregnancy and represent important contributors to maternal and neonatal morbidity and mortality worldwide. Preeclampsia (PE)\u2013eclampsia syndrome is the most important hypertensive gestational condition. Maternal ophthalmic artery Doppler velocimetry enables the identification of pregnant women with increased cerebral blood flow who are at risk of developing severe PE and eclampsia. Hence the need to determine the changes in ophthalmic artery Doppler velocimetric indices in PE in Kano, Nigeria becomes paramount.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Ninety-six patients with the clinical diagnosis of PE and 96 normotensive pregnant controls between 20 and 40 weeks\u2019 gestational age were recruited for this study. Ophthalmic artery Doppler velocimetric indices of the two groups were measured and documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean velocimetric measurements in the control group were as follows: peak systolic velocity (PSV) = 38.04 \u00b1 13.68 cm\/s, End-diastolic volume (EDV) =9.14 \u00b1 3.65 cm\/s, resistivity index (RI) = 0.75 \u00b1 0.091, pulsatility index (PI) =1.62 \u00b1 0.55, peak mesodiastolic velocity (PMDV) = 21.02 \u00b1 8.83 cm\/s, peak ratio (PR) = 0.56 \u00b1 0.14. The mean velocimetric indices in the PE group were PSV = 44.59 \u00b1 11.54 cm\/s, EDV = 12.23 \u00b1 2.66 cm\/s, RI = 0.71 \u00b1 0.069, PI = 1.67 \u00b1 0.42, PMDV = 32.27 \u00b1 9.12 and PR = 0.72 \u00b1 0.10.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>There is a significant difference in the ophthalmic artery Doppler velocimetric indices between women with PE and normal pregnant women. Ophthalmic artery Doppler ultrasound is a useful tool in monitoring the hemodynamic changes in cerebral circulation in PE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_26_21","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T06:13:35Z","timestamp":1682057615000},"page":"5-10","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Changes in Opthalmic Artery Doppler Velocimetry in Women with Preeclampsia in Kano, Nigeria"],"prefix":"10.4103","volume":"22","author":[{"given":"Mustapha Shu\u2019aibu","family":"Hikima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mansur Yahuza","family":"Adamu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf","family":"Lawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kabiru","family":"Isyaku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anas","family":"Isma\u2019il","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-2-20240831","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.bpobgyn.2016.05.005","article-title":"Preventing deaths due to the hypertensive disorders of pregnancy","volume":"36","author":"von Dadelszen","year":"2016","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"R3-2-20240831","doi-asserted-by":"crossref","first-page":"71","DOI":"10.5830\/CVJA-2016-009","article-title":"Pre-eclampsia: Its pathogenesis and pathophysiolgy","volume":"27","author":"Gathiram","year":"2016","journal-title":"Cardiovasc J Afr"},{"key":"R5-2-20240831","first-page":"197","article-title":"Immunology and genetic of preeclampsia","volume":"13","author":"Serrano","year":"2006","journal-title":"Clin Dev Immunol"},{"key":"R6-2-20240831","first-page":"467","article-title":"Pre-eclampsia: Pathophysiology, diagnosis, and management","volume":"7","author":"Uzan","year":"2011","journal-title":"Vasc Health Risk Manag"},{"key":"R7-2-20240831","doi-asserted-by":"crossref","first-page":"l2381","DOI":"10.1136\/bmj.l2381","article-title":"Pre-eclampsia: Pathophysiology and clinical implications","volume":"366","author":"Burton","year":"2019","journal-title":"BMJ"},{"key":"R8-2-20240831","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1146\/annurev-pathol-121808-102149","article-title":"Pathogenesis of preeclampsia","volume":"5","author":"Young","year":"2010","journal-title":"Annu Rev Pathol"},{"key":"R10-2-20240831","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0002-9378(97)70458-7","article-title":"Maternal ophthalmic artery Doppler velocimetry in normotensive pregnancies and pregnancies complicated by hypertensive disorders","volume":"177","author":"Hata","year":"1997","journal-title":"Am J Obstet Gynecol"},{"key":"R11-2-20240831","first-page":"16","article-title":"Ocular changes in preeclampsia","volume":"52","author":"Mihu","year":"2008","journal-title":"Oftalmologia"},{"key":"R12-2-20240831","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/uog.13313","article-title":"Predictive value of ophthalmic artery Doppler velocimetry in relation to development of pre-eclampsia","volume":"44","author":"Matias","year":"2014","journal-title":"Ultrasound Obstet Gynecol"},{"key":"R13-2-20240831","doi-asserted-by":"crossref","first-page":"563","DOI":"10.7863\/jum.2009.28.5.563","article-title":"Doppler velocimetry of the ophthalmic artery in normal pregnancy: Reference values","volume":"28","author":"de Oliveira","year":"2009","journal-title":"J Ultrasound Med"},{"key":"R15-2-20240831","doi-asserted-by":"crossref","first-page":"609","DOI":"10.7863\/jum.2013.32.4.609","article-title":"Changes in ophthalmic artery Doppler indices in hypertensive disorders during pregnancy","volume":"32","author":"de Oliveira","year":"2013","journal-title":"J Ultrasound Med"},{"key":"R16-2-20240831","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1067\/mob.2002.127594","article-title":"Transcranial Doppler measurement of cerebral velocity indices as a predictor of preeclampsia","volume":"187","author":"Riskin-Mashiah","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"R17-2-20240831","doi-asserted-by":"crossref","first-page":"128","DOI":"10.15557\/JoU.2019.0019","article-title":"Guidelines for ultrasound examination in ophthalmology. 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