{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:31:12Z","timestamp":1790188272493,"version":"4.1.0"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"\n Introduction:<\/jats:title>\n Postoperative nausea, vomiting, and cough are the most common adverse effects of general anesthesia resulting in high discomfort to the patient resulting in uneasiness during the recovery period. This study aimed to compare the influence of intraoperative use of sevoflurane and isoflurane on postoperative nausea, vomiting, and cough.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n After approval from the institutional ethical committee, this quantitative observational institutional study was conducted on all patients aged between 18 and 65 years undergoing surgery under general anesthesia at KMC Hospital, Mangalore. Patients were allocated into the sevoflurane group or isoflurane group.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n All demographic parameters such as age, sex, American Society of Anesthesiologists physical status, and duration were comparable (\n P<\/jats:italic>\n > 0.05). The sevoflurane group had higher number of patients (11 [14.86%]) with postoperative nausea at 0 h as compared isoflurane group (7 [9.45%]). Two patients in the isoflurane group reported postoperative vomiting at 0 h, whereas no patient in the sevoflurane group reported vomiting. For cough, a statistically significant correlation was seen between the two groups (\n P<\/jats:italic>\n = 0.000) with majority of patients in the isoflurane group, i.e., 50 (67.6%) patients reporting cough at 0 h while only 15 (20.3%) reported cough in the sevoflurane group.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Sevoflurane was found to be better than isoflurane in terms of postoperative nausea vomiting and cough immediately after emergence in our study. Isoflurane cause the emergence of cough whereas no significant difference in nausea and vomiting was observed in both groups.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/aam.aam_26_24","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:09Z","timestamp":1716422409000},"page":"385-390","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of the Influence of Intraoperative Use of Sevoflurane and Isoflurane on Postoperative Nausea, Vomiting, and Cough"],"prefix":"10.4103","volume":"23","author":[{"given":"Akansha","family":"Chouhan","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonal N","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil Vasudev","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,5,20]]},"reference":[{"key":"R1-20260507","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1213\/00000539-199411000-00006","article-title":"Cost comparison: A desflurane- versus a propofol-based general anesthetic technique","volume":"79","author":"Rosenberg","year":"1994","journal-title":"Anesth Analg"},{"key":"R2-20260507","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1213\/00000539-199611000-00005","article-title":"Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in pediatric ambulatory patients","volume":"83","author":"Welborn","year":"1996","journal-title":"Anesth Analg"},{"key":"R3-20260507","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1001\/jama.287.10.1233","article-title":"Postoperative nausea and vomiting \u2013 Can it be eliminated?","volume":"287","author":"Gan","year":"2002","journal-title":"JAMA"},{"key":"R5-20260507","doi-asserted-by":"crossref","first-page":"262","DOI":"10.18231\/j.ijca.2020.047","article-title":"Effect of single dose dexmedetomidine given prior to extubation on extubation conditions in adult patients following general anaesthesia","volume":"7","author":"Suresh","year":"2020","journal-title":"Indian J Clin Anaesthesia"},{"key":"R6-20260507","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1213\/ANE.0000000000000002","article-title":"Consensus guidelines for the management of postoperative nausea and vomiting","volume":"118","author":"Gan","year":"2014","journal-title":"Anesth Analg"},{"key":"R7-20260507","doi-asserted-by":"crossref","first-page":"110464","DOI":"10.1016\/j.jclinane.2021.110464","article-title":"Sevoflurane versus desflurane for early postoperative vomiting after general anesthesia in hospitalized adults: A systematic review and meta-analysis of randomized controlled trials","volume":"75","author":"Wang","year":"2021","journal-title":"J Clin Anesth"},{"key":"R8-20260507","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1034\/j.1399-6576.2000.440423.x","article-title":"Anaesthesia, recovery and postoperative nausea and vomiting after breast surgery. A comparison between desflurane, sevoflurane and isoflurane anaesthesia","volume":"44","author":"Karlsen","year":"2000","journal-title":"Acta Anaesthesiol Scand"},{"key":"R9-20260507","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1093\/bja\/88.5.659","article-title":"Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: A randomized controlled trial of factorial design","volume":"88","author":"Apfel","year":"2002","journal-title":"Br J Anaesth"},{"key":"R10-20260507","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1213\/00000539-199811000-00036","article-title":"Cough during emergence from isoflurane anesthesia","volume":"87","author":"Kim","year":"1998","journal-title":"Anesth Analg"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_26_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:39:47Z","timestamp":1787769587000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_26_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,20]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_26_24","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,20]]},"assertion":[{"value":"2024-01-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-11","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}