{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:23:06Z","timestamp":1787840586328,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Massive pulmonary embolism (PE) is a potential noncardiac cause of cardiac arrest with unfavorable prognosis. Maintaining a high degree of clinical suspicion, use of bedside focused cardiac ultrasound and computed tomography pulmonary angiography (CTPA) aid in rapid management. Thrombolytic therapy with anticoagulation is indicated in treatment of massive PE provided that there are no contraindications and there is low risk of bleeding. We present a case of massive PE with multiple cardiac arrests who successfully responded to systemic thrombolysis along with anticoagulation, barring a moderate bleeding complication.<\/jats:p>","DOI":"10.4103\/aam.aam_273_24","type":"journal-article","created":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T03:00:06Z","timestamp":1742007606000},"page":"925-928","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Case of Acute Massive Pulmonary Embolism with Multiple Cardiac Arrests and Successful Systemic Thrombolysis"],"prefix":"10.4103","volume":"24","author":[{"given":"S. Mohammed Mahaboob","family":"Pasha","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Nizwa Hospital, MoH, Nizwa, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bony","family":"Baiju","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Critical Care, Nizwa Hospital, MoH, Nizwa, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boban","family":"Varghese","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Critical Care, Nizwa Hospital, MoH, Nizwa, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajin A.","family":"Sunny","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nizwa Hospital, MoH, Nizwa, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"R1-20251015","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.ihj.2018.01.014","article-title":"Cardiac arrest due to pulmonary embolism","volume":"70","author":"Laher","year":"2018","journal-title":"Indian Heart J"},{"key":"R2-20251015","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/eurheartj\/ehz405","article-title":"2019 ESC guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS)","volume":"41","author":"Konstantinides","year":"2020","journal-title":"Eur Heart J"},{"key":"R3-20251015","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1182\/bloodadvances.2020003442","article-title":"American Society of Hematology 2021 guidelines for management of venous thromboembolism: Prevention and treatment in patients with cancer","volume":"5","author":"Lyman","year":"2021","journal-title":"Blood Adv"},{"key":"R4-20251015","doi-asserted-by":"crossref","first-page":"4098","DOI":"10.12998\/wjcc.v11.i17.4098","article-title":"Cardiac arrest secondary to pulmonary embolism treated with extracorporeal cardiopulmonary resuscitation: Six case reports","volume":"11","author":"Qiu","year":"2023","journal-title":"World J Clin Cases"},{"key":"R5-20251015","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.athoracsur.2020.02.024","article-title":"National outcomes of surgical embolectomy for acute pulmonary embolism","volume":"110","author":"Percy","year":"2020","journal-title":"Ann Thorac Surg"},{"key":"R6-20251015","doi-asserted-by":"crossref","first-page":"1298686","DOI":"10.3389\/fcvm.2023.1298686","article-title":"Current status of ECMO for massive pulmonary embolism","volume":"10","author":"Davies","year":"2023","journal-title":"Front Cardiovasc Med"},{"key":"R7-20251015","first-page":"CD010222","article-title":"Anticoagulant treatment for subsegmental pulmonary embolism","volume":"2","author":"Yoo","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"R8-20251015","doi-asserted-by":"crossref","first-page":"e545","DOI":"10.1016\/j.chest.2021.07.055","article-title":"Antithrombotic therapy for VTE disease: Second update of the CHEST guideline and expert panel report","volume":"160","author":"Stevens","year":"2021","journal-title":"Chest"},{"key":"R9-20251015","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.thromres.2023.09.009","article-title":"Major in-hospital bleeding in patients with pulmonary embolism treated with systemic thrombolysis","volume":"231","author":"Mavromanoli","year":"2023","journal-title":"Thromb Res"},{"key":"R10-20251015","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.15420\/usc.2024.11","article-title":"Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support","volume":"18","author":"Okumus","year":"2024","journal-title":"US Cardiol"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_273_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:25:32Z","timestamp":1787837132000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_273_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,13]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_273_24","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,13]]},"assertion":[{"value":"2024-12-07","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}