{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:22:10Z","timestamp":1787764930004,"version":"build-2784847793"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>\n                      The World Health Organization has identified carbapenem-resistant\n                      <jats:italic toggle=\"yes\">Acinetobacter baumannii<\/jats:italic>\n                      (CRAB) infections as the most important pathogens for which new antibiotics must be developed immediately. Therefore, this study aimed to analyze the comparison of epidemiology, microbial pattern, and antibiotic resistance in CRAB and carbapenem-sensitive\n                      <jats:italic toggle=\"yes\">A<\/jats:italic>\n                      .\n                      <jats:italic toggle=\"yes\">baumannii<\/jats:italic>\n                      (CSAB).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A retrospective cohort study was used, with community-acquired pneumonia with\n                      <jats:italic toggle=\"yes\">A<\/jats:italic>\n                      .\n                      <jats:italic toggle=\"yes\">baumannii<\/jats:italic>\n                      bacterial culture results. Data were obtained from the patient\u2019s medical record and the results of antibiotic sensitivity testing with the culture method by planting sputum on blood agar and MacConkey medium for 24 h.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 50 patients, CRAB (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 26) and CSAB (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 24), found that the average gender was male in CRAB compared to CSAB (69.2% vs. 48.2%). Complications of respiratory failure, sepsis, and acute respiratory distress syndrome were higher in CRAB compared to CSAB (30.8% vs. 20.8%, 46.2% vs. 25%, and 2% vs. 0%). The mortality rate in the CRAB group was 53.8% vs. CSAB 12.5%. The mean length of stay (LOS) in CRAB was 17.92, while CSAB was 11.00. The mean cost of hospitalization in CRAB was higher than CSAB ($6993.0615 vs. $3263.7375). The mean neutrophil-to-lymphocyte ratio value in the CRAB group was 20.4, while in CSAB was 10.6.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The results indicated that CRAB infection carries a greater burden in terms of cost of treatment, mortality, LOS, and more serious complications, compared to CSAB infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_304_24","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T15:05:39Z","timestamp":1754319939000},"page":"909-915","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Demystify Carbapenem-resistant Acinetobacter baumannii Pneumonia Burden: 2-Year Cohort Study"],"prefix":"10.4103","volume":"24","author":[{"given":"Alfian Nur","family":"Rosyid","sequence":"first","affiliation":[{"name":"Department of Pulmonology and Respiratory Medicine, Universitas Airlangga Hospital, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pepy Dwi","family":"Endraswari","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Firman","family":"Setiawan","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yessy","family":"Puspitasari","sequence":"additional","affiliation":[{"name":"Yannas Husada Health Vocational School, Bangkalan, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tri Pudy","family":"Asmarawati","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian Eka","family":"Rachman","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arina Dery","family":"Puspitasari","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad Mufid","family":"Sultoni","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prastuti Asta","family":"Wulaningrum","sequence":"additional","affiliation":[{"name":"Department of 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