{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T13:21:22Z","timestamp":1788182482704,"version":"build-2803163510"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Local anesthetics (LAs) are integral to surgical and diagnostic procedures, with allergic reactions being rare yet potentially life-threatening. We report a case of a 69-year-old male with chronic obstructive pulmonary disease and suspected lignocaine allergy, posted for transurethral resection of the prostate. Intradermal testing revealed a positive reaction to lignocaine but a negative response to preservative-free bupivacaine heavy. Based on this, spinal anesthesia was planned with bupivacaine heavy and fentanyl, along with prophylactic corticosteroids and antihistamines. The surgery proceeded uneventfully. This case highlights the critical role of intradermal sensitivity testing with the intended local anesthetic drug in preventing allergic reactions and guiding safe anesthetic management. Individualized assessment, careful interpretation of test results, and preparedness are key to ensuring patient safety in cases of suspected LA hypersensitivity.<\/jats:p>","DOI":"10.4103\/aam.aam_313_25","type":"journal-article","created":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T12:00:08Z","timestamp":1771848008000},"page":"1347-1349","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Suspected Lignocaine Allergy: Safe Conduct of Spinal Anesthesia with Bupivacaine"],"prefix":"10.4103","volume":"25","author":[{"given":"Aparna","family":"Bagle","sequence":"first","affiliation":[{"name":"Anesthesia, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Raj","sequence":"additional","affiliation":[{"name":"Anesthesia, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amala","family":"Kale","sequence":"additional","affiliation":[{"name":"Anesthesia, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,20]]},"reference":[{"key":"R1-20260831","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1093\/bja\/aes162","article-title":"IgE-mediated allergy to local anaesthetics: Separating fact from perception: A UK perspective","volume":"108","author":"Bhole","year":"2012","journal-title":"Br J Anaesth"},{"key":"R2-20260831","doi-asserted-by":"crossref","first-page":"90","DOI":"10.2344\/0003-3006-59.2.90","article-title":"Local anesthetics: Review of pharmacological considerations","volume":"59","author":"Becker","year":"2012","journal-title":"Anesth Prog"},{"key":"R4-20260831","first-page":"105","article-title":"Anaphylaxis to local anesthetic agents: A case report and review of literature","volume":"8","author":"Bhargava","year":"2014","journal-title":"Saudi J Anaesth"},{"key":"R5-20260831","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s40981-019-0302-6","article-title":"Mepivacaine-induced anaphylactic shock in a pregnant woman undergoing combined spinal and epidural anesthesia for cesarean delivery: A case report","volume":"5","author":"Takahashi","year":"2019","journal-title":"JA Clin Rep"},{"key":"R6-20260831","first-page":"UD01","article-title":"Near fatal anaphylactoid reaction due to bupivacaine spinal anaesthesia","volume":"12","author":"Singh","year":"2018","journal-title":"J Clin Diagn Res"},{"key":"R7-20260831","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.ijscr.2020.11.044","article-title":"Articaine as an alternative in lidocaine allergy: Case report of a seventy year old male patient","volume":"77","author":"Dey","year":"2020","journal-title":"Int J Surg Case Rep"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_313_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T13:01:03Z","timestamp":1788181263000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_313_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,20]]},"references-count":6,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_313_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,20]]},"assertion":[{"value":"2025-07-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-29","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}