{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:51:24Z","timestamp":1791445884954,"version":"4.3.3"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Context:<\/jats:title>\n Magnesium is a primary intracellular cation involved in glucose metabolism, insulin signaling, and lipid regulation. Hypomagnesemia contributes to insulin resistance and atherogenic dyslipidemia.<\/jats:p>\n <\/jats:sec>\n \n Aims:<\/jats:title>\n The study aimed to examine the correlation between serum magnesium levels and insulin resistance and dyslipidemia among type 2 diabetes mellitus (T2DM) patients.<\/jats:p>\n <\/jats:sec>\n \n Settings and Design:<\/jats:title>\n Three hundred and seventy-five patients with T2DM were included in this cross-sectional study.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Serum magnesium levels were categorized as Group 1: <1.7 mg\/dL, Group 2: between 1.7 and 2.7 mg\/dL, and Group 3: >2.7 mg\/dL. The data were measured in terms of anthropometric record, glycemic parameters, lipid profile, kidney markers, and homeostatic model assessment for insulin resistance (HOMA-IR).<\/jats:p>\n <\/jats:sec>\n \n Statistical Analysis Used:<\/jats:title>\n Statistical analysis involved the use of analysis of variance, Chi-square, Pearson\u2019s correlation, and linear regression modeling.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The prevalence of hypomagnesemia (<1.7 mg\/dL) was 35.7%. Although group-wise variations in HOMA-IR were not statistically significant, multivariable linear regression analyses adjusted for age, sex, and body mass index demonstrated that serum magnesium remained significantly associated with postprandial plasma glucose (PPG) (\u03b2 = 19.01, 95% confidence interval [CI]: 5.94\u201332.08;\n P<\/jats:italic>\n = 0.004) and low-density lipoprotein cholesterol (\u03b2 = 7.60, 95% CI: 3.08\u201312.11;\n P<\/jats:italic>\n = 0.001). Patients with lower serum magnesium levels had a higher prevalence of microvascular complications, particularly nephropathy and retinopathy.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Serum magnesium levels were associated with glycemic control, lipid profile, renal functioning, and microvascular complications in T2DM. Periodic surveillance and possible correction of magnesium deficiency may represent a potential complementary approach requiring further evaluation.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/aam.aam_345_26","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:00:15Z","timestamp":1791442815000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Association of Serum Magnesium, Insulin Resistance, and Atherogenic Dyslipidemia in Type 2 Diabetes Mellitus: A Cross-Sectional Analysis"],"prefix":"10.4103","author":[{"given":"Satyendra","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Medicine, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurabh","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Medicine, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh, India"},{"name":"Department of Medical Research, Multidisciplinary Research Unit, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti","family":"Solanki","sequence":"additional","affiliation":[{"name":"Department of Medicine, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Medicine, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Department of Medical Research, Multidisciplinary Research Unit, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamta","family":"Padhy","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,10,7]]},"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_345_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:00:17Z","timestamp":1791442817000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_345_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,7]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4103\/aam.aam_345_26","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,7]]},"assertion":[{"value":"2026-03-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}