{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:33:20Z","timestamp":1787776400630,"version":"build-2784847793"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Malignancy at the gastrojejunostomy site, though rare, is a recognized long-term risk factor of the procedure. Such malignancies, though uncommon, pose diagnostic and therapeutic challenges. We report a case of a 63-year-old male presenting with a rare complication of gastric carcinoma at the loop gastrojejunostomy site 30 years after surgery for duodenal ulcer-induced gastric outlet obstruction. The patient\u2019s symptoms included chronic intermittent upper abdominal pain, postprandial bilious vomiting, significant weight loss, and anorexia. The diagnosis was established through imaging and endoscopic biopsy, revealing a poorly differentiated carcinoma. Following preoperative optimization, the patient underwent subtotal radical gastrectomy with Roux-en-Y reconstruction with D2 lymphadenectomy. Histopathology confirmed poorly cohesive gastric carcinoma (signet ring cell type) with extensive lymph node metastasis (pT4a pN3a M0). Postoperative recovery was uneventful, and the patient was discharged on a CAPEOX regimen for adjuvant chemotherapy. This case highlights the importance of vigilance in patients with long-standing gastrojejunostomy, given the risk of malignancy at the anastomotic site.<\/jats:p>","DOI":"10.4103\/aam.aam_41_25","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T12:00:11Z","timestamp":1748606411000},"page":"204-207","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Gastric Adenocarcinoma at the Anastomotic Site Three Decades after Gastrojejunostomy: A Case Report with Literature Review"],"prefix":"10.4103","volume":"25","author":[{"given":"Raghav","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of General Surgery, Dr. D. Y. Patil Hospital and Research Center, Pimpri-Chinchwad, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun Teja","family":"Pudota","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Dr. D. Y. Patil Hospital and Research Center, Pimpri-Chinchwad, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhat Bhaskarrao","family":"Nichkaode","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Dr. D. Y. 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Report of a case","volume":"17","author":"Takeno","year":"2000","journal-title":"Dig Surg"},{"key":"R11-20260109","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0306-9877(79)90112-9","article-title":"Gastric carcinoma promoted by alkaline reflux gastritis \u2013With special reference to bile and other surfactants as promoters of postoperative gastric cancer","volume":"5","author":"Domell\u00f6f","year":"1979","journal-title":"Med Hypotheses"},{"key":"R12-20260109","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1007\/s10120-023-01423-z","article-title":"Multicenter phase II study of capecitabine plus oxaliplatin in older patients with advanced gastric cancer: The Tokyo Cooperative Oncology Group (TCOG) GI-1601 study","volume":"26","author":"Kawabata","year":"2023","journal-title":"Gastric Cancer"},{"key":"R13-20260109","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.ejca.2011.12.017","article-title":"A randomized phase II trial of S-1-oxaliplatin versus capecitabine-oxaliplatin in advanced gastric cancer","volume":"48","author":"Kim","year":"2012","journal-title":"Eur J Cancer"},{"key":"R14-20260109","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3892\/mco.2017.1335","article-title":"First-line chemotherapy with capecitabine\/oxaliplatin for advanced gastric cancer: A phase I study","volume":"7","author":"Satake","year":"2017","journal-title":"Mol Clin Oncol"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_41_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:10:45Z","timestamp":1787775045000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_41_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,30]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_41_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,30]]},"assertion":[{"value":"2025-02-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-25","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}