{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:17:46Z","timestamp":1783419466561,"version":"3.54.6"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Acute epididymo-orchitis (EO) is a common inflammatory condition of the male genitourinary tract and a frequent cause of acute scrotal pain. Understanding its etiopathogenesis, clinical profile, and management outcomes is essential for preventing complications and ensuring optimal recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The objective of this study was to evaluate the etiopathogenesis, demographic profile, and management outcomes of acute EO in a tertiary care hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective observational analytical study was conducted over 30 months at a tertiary care center. Seventy patients aged 18\u201370 years diagnosed with acute EO were enrolled. Demographic characteristics, risk factors, clinical features, laboratory findings, ultrasonographic findings, management approaches, and short-term outcomes were analyzed using descriptive statistics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean age was 37.3 \u00b1 13.03 years, with the highest incidence in the 31\u201340-year group (32.9%). Scrotal pain and tenderness were present in all patients (100%), followed by fever (87.1%) and swelling (82.9%). Left-sided involvement predominated (60.0%). Common predisposing factors included urinary tract infection (31.4%), obstructed uropathy or prior instrumentation (24.3%), trauma (21.4%), and diabetes mellitus (22.9%). Pyuria (50.0%), leukocytosis (51.4%), and positive urine cultures (38.6%) were frequent, with\n                      <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                      being the predominant organism. Doppler ultrasonography confirmed inflammatory changes in all cases, with reactive hydrocele observed in 31.4%. Most patients (87.1%) had no complications. Conservative treatment was effective in 97.1% of cases, with a significant reduction in pain scores within 84 h and near-complete clinical recovery by 4\u20136 weeks.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Acute EO predominantly affects young to middle-aged men and responds well to early conservative management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_432_26","type":"journal-article","created":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:00:21Z","timestamp":1783418421000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Profile and Management of Acute Epididymo-orchitis in a Tertiary Care Hospital: A Prospective Observational Study"],"prefix":"10.4103","author":[{"given":"Shreya Reddy","family":"Nagula","sequence":"first","affiliation":[{"name":"Department of General Surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Vidyapeeth (Deemed to be University), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayesh","family":"Khadse","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Vidyapeeth (Deemed to be University), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,7,7]]},"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.4103\/aam.aam_432_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:00:21Z","timestamp":1783418421000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.4103\/aam.aam_432_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,7]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4103\/aam.aam_432_26","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,7]]},"assertion":[{"value":"2026-04-15","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-14","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}