{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:33:02Z","timestamp":1786116782321,"version":"build-2736575974"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Upper gastrointestinal bleeding (UGIB) in chronic liver disease (CLD) carries a high risk and requires early stratification. This study evaluated the prognostic value of the AIMS65 score in CLD patients with UGIB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective observational study included 131 adult CLD patients with UGIB admitted over 18 months at Rajendra Institute of Medical Sciences, Ranchi. Patients were grouped as AIMS65 &lt;3 and AIMS65 \u22653. The primary outcome was inhospital mortality; secondary outcomes were intensive care unit (ICU) admission, rebleeding, and length of hospital stay. Mortality prediction by AIMS65 was compared with Child\u2013Pugh and model for end-stage liver disease (MELD) scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The median age was 54 years (interquartile range: 46\u201363), and 54.9% were male. Variceal bleeding was present in 68.0% of patients. Compared with AIMS65 &lt;3, patients with AIMS65 \u22653 had higher inhospital mortality (31.3% vs. 4.7%), ICU admission (50.7% vs. 12.5%), rebleeding (40.3% vs. 7.8%), and longer hospital stay (13.5 \u00b1 3.8 vs. 7.3 \u00b1 2.1 days) (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). AIMS65 showed the highest discrimination for inhospital mortality (area under the curve: 0.88; 95% confidence interval [CI]: 0.80\u20130.95), compared with Child\u2013Pugh (0.84; 95% CI: 0.75\u20130.92) and MELD (0.81; 95% CI: 0.72\u20130.90).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Higher AIMS65 scores were associated with adverse inhospital outcomes in CLD patients with UGIB. AIMS65 showed better mortality discrimination than Child\u2013Pugh and MELD in this cohort and may be a useful bedside risk stratification tool.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_463_26","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T12:01:30Z","timestamp":1786017690000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["AIMS65 Score as a Predictor of Inhospital Outcomes in Patients with Chronic Liver Disease Presenting with Upper Gastrointestinal Bleeding"],"prefix":"10.4103","author":[{"given":"Smriti","family":"Bharti","sequence":"first","affiliation":[{"name":"Department of Medicine, Sheikh Bhikhari Medical College and Hospital, Hazaribag, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gagan","family":"Gunjan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pragya","family":"Pant","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand","family":"Dev","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Indira Gandhi Institute of Medical Sciences, Sheikhpura, Patna, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bindey","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,8,6]]},"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_463_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T12:01:30Z","timestamp":1786017690000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_463_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,6]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4103\/aam.aam_463_26","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,6]]},"assertion":[{"value":"2026-04-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}