{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T12:33:01Z","timestamp":1787142781323,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:00:00Z","timestamp":1764633600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A 34-year-old lactating woman presented with erythematous indurated plaques around the perioral region, extending to the nose and forehead, mimicking granulomatous dermatoses. Dermoscopy showed follicular plugging and dermal inflammation. Histopathology revealed epithelioid cell granulomas with giant cells and nerve infiltration, confirming borderline tuberculoid leprosy. The patient was treated with multidrug therapy and closely monitored for reactions. This case underscores the diagnostic challenge of Hansen\u2019s disease with atypical centrofacial presentation and emphasizes the importance of histopathological confirmation for timely treatment, particularly in vulnerable groups such as lactating mothers.<\/jats:p>","DOI":"10.4103\/aam.aam_491_25","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T10:00:08Z","timestamp":1764583208000},"page":"S53-S55","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["The Mystery Plaque: Unraveling a Singular Perioral Granulomatous Enigma"],"prefix":"10.4103","volume":"25","author":[{"given":"Nishtha","family":"Mishra","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarthak","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asharbh","family":"Raman","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gauri","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,2]]},"reference":[{"key":"R2-20260819","first-page":"8652062","article-title":"Leprosy: A review of epidemiology, clinical diagnosis, and management","author":"Chen","year":"2022","journal-title":"J Trop Med 2022"},{"key":"R3-20260819","first-page":"405","article-title":"Global Leprosy Update, 2015: Time for Action, Accountability and Inclusion","volume":"91","year":"2016","journal-title":"Wkly Epidemiol Rec Relev \u00e9pid\u00e9miologique Hebd"},{"key":"R4-20260819","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1471-2334-12-S1-P36","article-title":"Tuberculoid Hansen's \u2013 A Case Report","volume":"12","author":"Padmanaban","year":"2012","journal-title":"BMC Infect Dis"},{"key":"R5-20260819","doi-asserted-by":"crossref","first-page":"483","DOI":"10.4269\/ajtmh.22-0637","article-title":"Case report: Borderline lepromatous leprosy therapy complicated by type 1 leprosy reaction and adverse reactions with dapsone and clofazimine","volume":"110","author":"Matono","year":"2024","journal-title":"Am J Trop Med Hyg"},{"key":"R6-20260819","doi-asserted-by":"crossref","first-page":"356","DOI":"10.4103\/0378-6323.159929","article-title":"A randomized controlled trial to compare cure and relapse rate of paucibacillary multidrug therapy with monthly rifampicin, ofloxacin, and minocycline among paucibacillary leprosy patients in Agra District, India","volume":"81","author":"Kumar","year":"2015","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R7-20260819","first-page":"20499361221135885","article-title":"Novel approaches in the treatment of Hansen's disease (Leprosy): A case series of multidrug therapy of monthly rifampin, moxifloxacin, and minocycline (RMM) in the United States","volume":"9","author":"Franco-Paredes","year":"2022","journal-title":"Ther Adv Infect Dis"},{"key":"R8-20260819","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1600-0757.2011.00396.x","article-title":"Bi-directional relationship between pregnancy and periodontal disease","volume":"61","author":"Armitage","year":"2013","journal-title":"Periodontol 2000"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_491_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T12:01:23Z","timestamp":1787140883000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_491_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,2]]},"references-count":7,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_491_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,2]]},"assertion":[{"value":"2025-09-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-05","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}