{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:32:23Z","timestamp":1787776343499,"version":"build-2784847793"},"reference-count":54,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The aortic root is an aggregate of various components that connects the left ventricle to the aorta. The most predominant pathologies have been associated with the dilation of the aortic root leading to aneurysms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study is designed to measure the role of systemic morbidities such as hypertension, diabetes, and body mass index (BMI) on the dimension of the aortic root.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Participants were volunteers of African descent who were recruited during and after an organized health fair by the medical students\u2019 body from All Saints University, School of Medicine. 169 participants consisting of 62 males and 107 females with ages ranging from 9 to 84 years agreed to volunteer by signing the consent after which a questionnaire was administered and a preliminary clinical procedure was used to check for blood pressure (BP), blood glucose (BG), and BMI. The measurement of the aortic root was carried out by an experienced single investigator who was not aware of the purpose of measurements, using a DUS-5000 ultrasound machine (Miami, Florida, USA) at a low-frequency micro-convex transducer preset to \u201cadult cardiac\u201d with a default frequency of 4 MHz.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among the participants, 35.03%, 47.80%, and 29.11% had normal BP, BG, and BMI readings, respectively. The Chi-squared analysis identified a significant correlation between the diameter of the aortic annulus (AA) and BMI. Diastolic BP is also correlated with the diameter of the AA. Sinus of Valsalva (SV) showed an unusual correlation with BG as opposed to BP and BMI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The disparity in how a systemic factor individually correlates with the AA and the SV is not clear. The study targets to provide educational concept in this regard.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_51_17","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T05:40:42Z","timestamp":1535694042000},"page":"133-139","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Correlating Possible Predisposing Demographics and Systemic Conditions with the Aortic Root"],"prefix":"10.4103","volume":"17","author":[{"given":"Adegbenro Omotuyi John","family":"Fakoya","sequence":"first","affiliation":[{"name":"Department of Anatomical Sciences, University of Medicine and Health Sciences, St. Kitts and Nevis, Roseau, Dominica"},{"name":"Department of Anatomical Sciences, School of Medicine, All Saints University, Roseau, Dominica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Adeiza","family":"Otohinoyi","sequence":"additional","affiliation":[{"name":"Medical Student, School of Medicine, All Saints University, Roseau, Dominica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adekunle Ebenezer","family":"Omole","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Sciences, American University of Antigua, College of Medicine, St. John's, Antigua"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Oladele","sequence":"additional","affiliation":[{"name":"Medical Student, School of Medicine, All Saints University, Roseau, Dominica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayoola","family":"Kalejaiye","sequence":"additional","affiliation":[{"name":"Medical Student, School of Medicine, All Saints University, Roseau, Dominica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel","family":"Onuegbu","sequence":"additional","affiliation":[{"name":"Medical Student, School of Medicine, All Saints University, Roseau, Dominica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Nwalie","sequence":"additional","affiliation":[{"name":"Medical Student, School of Medicine, All Saints University, Roseau, Dominica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debjyoti","family":"Talukdar","sequence":"additional","affiliation":[{"name":"Medical Student, School of Medicine, All Saints University, Roseau, Dominica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omowaninuola","family":"Erinkitola","sequence":"additional","affiliation":[{"name":"Medical Student, School of Medicine, All Saints University, Roseau, Dominica"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250528","article-title":"The surgical anatomy of the aortic root","volume":"2007","author":"Anderson","year":"2007","journal-title":"Multimed Man Cardiothorac Surg"},{"key":"R2-20250528","first-page":"53","article-title":"Anatomy of the aortic root: Implications for valve-sparing surgery","volume":"2","author":"Charitos","year":"2013","journal-title":"Ann Cardiothorac Surg"},{"key":"R3-20250528","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/217086b0","article-title":"Mechanism of closure of the aortic valve","volume":"217","author":"Bellhouse","year":"1968","journal-title":"Nature"},{"key":"R4-20250528","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0022-5223(19)40069-X","article-title":"The dynamic aortic root. 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