{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:32:44Z","timestamp":1786649564855,"version":"build-2736575974"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>\n                      The present study aims to compare the clinical efficacy of Emdogain\n                      <jats:sup>\u00ae<\/jats:sup>\n                      and Recombinant human bone morphogenetic protein-2 (rhBMP-2), adjunctive to Titanium prepared platelet-rich fibrin (T-PRF), in the treatment of gingival recession with the coronally advanced flap (CAF) technique.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods:<\/jats:title>\n                    <jats:p>\n                      The present study is a randomized controlled trial. A Total of 26 patients with gingival recession were assigned randomly into two groups. Group \u2160: 13 gingival recession sites with CAF technique, Emdogain\n                      <jats:sup>\u00ae<\/jats:sup>\n                      , and T-PRF. Group \u2161: 13 gingival recession sites with CAF, rhBMP-2, and T-PRF. The clinical parameters recorded at the baseline and 9 months were recession depth (RD), probing depth (PD), clinical attachment level (CAL), and keratinized tissue width (KTW).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Analysis:<\/jats:title>\n                    <jats:p>\n                      Paired\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test for intragroup differences, Independent samples\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test for intergroup differences, and Levene\u2019s test for equality of variances were used.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The clinical parameters like PD, CAL, KTW, and RD in the present trial revealed a significant reduction when compared from baseline to 9 months in both groups. In intragroup comparison, all parameters showed statistical significance (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.005). In intergroup comparison, the KTW improvement was higher in Group \u2160 when compared to Group \u2161.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      In conclusion, both groups seem to be valuable treatment options for gingival recession. The biomaterials Emdogain\n                      <jats:sup>\u00ae<\/jats:sup>\n                      , rhBMP-2, and T-PRF showed promising results in the root coverage procedure.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/aam.aam_588_25","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T12:00:35Z","timestamp":1766577635000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Evaluation of Emdogain\u00ae with Titanium Prepared Platelet-rich Fibrin and Recombinant Human Bone Morphogenetic Protein-2 with Titanium Prepared Platelet-rich Fibrin in the Treatment of Gingival Recession \u2013 A Randomized Controlled Trial"],"prefix":"10.4103","author":[{"given":"Harish Prabhudev","family":"Pillutla","sequence":"first","affiliation":[{"name":"Department of Periodontics, St. Joseph Dental College, Eluru, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aravind Kumar","family":"Pavuluri","sequence":"additional","affiliation":[{"name":"Department of Periodontics, St. Joseph Dental College, Eluru, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph Kishore","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Periodontics, St. Joseph Dental College, Eluru, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mounisha","family":"Kondepati","sequence":"additional","affiliation":[{"name":"Department of Periodontics, St. Joseph Dental College, Eluru, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samanvitha","family":"Yerra","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, GSL Dental College, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,24]]},"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_588_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:55:29Z","timestamp":1786647329000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_588_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,24]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4103\/aam.aam_588_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,24]]},"assertion":[{"value":"2025-09-29","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-27","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}