{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:22:35Z","timestamp":1787775755378,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:00:00Z","timestamp":1772582400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Hereditary hemorrhagic telangiectasia is a disorder of blood vessels characterized by angiogenesis and chronic dilatation. Hereby presenting a case of an elderly female presenting with recurrent epistaxis with spontaneous resolution, multiple episodes of per rectal bleed since the past 10 years, leading to chronic anaemia and required blood transfusions. Further evaluation revealed the presence of multiple nasal, gastric, and colonic telangiectasias without active bleeding and complex pulmonary arteriovenous malformations. The patient was transfused with five pints of packed cell volume, cauterization done in view of nasal telangiectasia, and started on oral form of thalidomide 50 mg once daily to prevent angiogenesis, further progression, and complications.<\/jats:p>","DOI":"10.4103\/aam.aam_683_25","type":"journal-article","created":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T12:01:19Z","timestamp":1772625679000},"page":"S138-S140","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["An Interesting Case of Hereditary Hemorrhagic Telangiectasia in a Patient with Recurrent Epistaxis"],"prefix":"10.4103","volume":"25","author":[{"given":"Vijayashree S.","family":"Gokhale","sequence":"first","affiliation":[{"name":"Department of General Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avuthu","family":"Hemanjali","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divam Prakash","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Triveen Varma","family":"Vetukuri","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,3,4]]},"reference":[{"key":"R1-20260819","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5409\/wjcp.v10.i1.1","article-title":"Hereditary hemorrhagic telangiectasia presenting as a recurrent epistaxis in an adolescent: A case report","volume":"10","author":"Acharya","year":"2021","journal-title":"World J Clin Pediatr"},{"key":"R2-20260819","article-title":"Hereditary hemorrhagic telangiectasia (HHT)","author":"Locke","year":"2022","journal-title":"In: StatPearls"},{"key":"R3-20260819","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.3324\/haematol.2018.193003","article-title":"Hereditary hemorrhagic telangiectasia: Diagnosis and management from the hematologist's perspective","volume":"103","author":"Kritharis","year":"2018","journal-title":"Haematologica"},{"key":"R4-20260819","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1002\/alr.22094","article-title":"Medical treatment of epistaxis in hereditary hemorrhagic telangiectasia: An evidence-based review","volume":"8","author":"Halderman","year":"2018","journal-title":"Int Forum Allergy Rhinol"},{"key":"R5-20260819","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1007\/s10620-017-4719-3","article-title":"Gastrointestinal manifestations of hereditary hemorrhagic telangiectasia (HHT): A systematic review of the literature","volume":"62","author":"Jackson","year":"2017","journal-title":"Dig Dis Sci"},{"key":"R6-20260819","doi-asserted-by":"crossref","first-page":"E12","DOI":"10.1542\/peds.109.1.e12","article-title":"Intracranial hemorrhage in infants and children with hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome)","volume":"109","author":"Morgan","year":"2002","journal-title":"Pediatrics"},{"key":"R7-20260819","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/(SICI)1096-8628(20000306)91:1<66::AID-AJMG12>3.0.CO;2-P","article-title":"Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome)","volume":"91","author":"Shovlin","year":"2000","journal-title":"Am J Med Genet"},{"key":"R8-20260819","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/ejhg.2009.35","article-title":"Hereditary haemorrhagic telangiectasia: A clinical and scientific review","volume":"17","author":"Govani","year":"2009","journal-title":"Eur J Hum Genet"},{"key":"R9-20260819","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fgene.2015.00001","article-title":"Hereditary hemorrhagic telangiectasia: Genetics and molecular diagnostics in a new era","volume":"6","author":"McDonald","year":"2015","journal-title":"Front Genet"},{"key":"R10-20260819","first-page":"157","article-title":"Diagnosis and treatment of hereditary hemorrhagic telangiectasia","volume":"17","author":"Grigg","year":"2017","journal-title":"Ochsner J"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_683_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:41:13Z","timestamp":1787773273000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_683_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,4]]},"references-count":10,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_683_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,4]]},"assertion":[{"value":"2025-10-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}