{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T07:58:15Z","timestamp":1790409495562,"version":"4.1.0"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Background:<\/jats:title>\n \n Chlamydia trachomatis<\/jats:italic>\n is the most common bacterial sexually transmitted infection worldwide, often asymptomatic but associated with adverse maternal and perinatal outcomes. Limited data are available from India regarding intrapartum infection and its clinical implications.\n <\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n \n The aim is to determine the prevalence of intrapartum\n C. trachomatis<\/jats:italic>\n infection and its correlation with obstetric and perinatal outcomes.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n This prospective observational study included 147 pregnant women admitted for delivery at a tertiary care center. Endocervical swabs were collected intrapartum and tested for\n C. trachomatis<\/jats:italic>\n using polymerase chain reaction. Maternal and neonatal outcomes, including gestational age at delivery, puerperal sepsis, early-onset neonatal sepsis (EOS), low birth weight (LBW), neonatal intensive care unit (NICU) admission, stillbirth, and neonatal death, were recorded. Statistical analysis was performed using SPSS version 25.0, with\n P<\/jats:italic>\n < 0.05 considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The prevalence of intrapartum\n C. trachomatis<\/jats:italic>\n infection was 19.7% (29\/147). Preterm delivery was significantly higher among infected women (27.6% vs. 11.9%,\n P<\/jats:italic>\n = 0.04). Puerperal sepsis occurred in 17.2% of infected women compared to 3.4% of uninfected women (\n P<\/jats:italic>\n = 0.01). EOS was observed in 20.7% of neonates born to infected mothers versus 6.8% of those born to uninfected mothers (\n P<\/jats:italic>\n = 0.02). LBW was more frequent among neonates of infected mothers (31.0% vs. 12.7%,\n P<\/jats:italic>\n = 0.03) and NICU admissions were also significantly higher (24.1% vs. 10.2%,\n P<\/jats:italic>\n = 0.04). Although stillbirth (6.9% vs. 1.7%) and neonatal death (3.4% vs. 0.8%) were more common in the positive group, these were not statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n Intrapartum\n C. trachomatis<\/jats:italic>\n infection is common and significantly associated with preterm birth, puerperal sepsis, neonatal sepsis, LBW, and increased NICU admissions. Routine antenatal screening and timely treatment could substantially improve maternal and perinatal outcomes.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/aam.aam_704_25","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T07:00:18Z","timestamp":1790406018000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Correlation of Intrapartum Chlamydia trachomatis Infection with Obstetric and Perinatal Outcome"],"prefix":"10.4103","author":[{"given":"Tripti","family":"Kumari","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, King Georges Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kusum","family":"Lata","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Autonomous State Medical College, Hardoi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, King Georges Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjoo","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, King Georges Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,25]]},"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_704_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T07:00:18Z","timestamp":1790406018000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_704_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4103\/aam.aam_704_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,25]]},"assertion":[{"value":"2025-11-02","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-27","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}