{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T12:13:06Z","timestamp":1789560786362,"version":"build-2803163510"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Angiomyxoma is a rare, benign mesenchymal tumor rarely encountered in the infantile hard palate. This case report describes the presentation, diagnostic workup, and successful management of an angiomyxoma in an 11-month-old male infant. An 11-month-old male was presented to the ENT department with a slowly enlarging, asymptomatic palatal swelling first noticed at 9 months of age. Intraoral examination revealed a 2 cm \u00d7 2 cm, soft, nontender mass on the anterior hard palate. A contrast-enhanced computed tomography scan identified a well-defined, oval, heterogeneously enhancing cystic lesion (8 mm \u00d7 15 mm \u00d7 18 mm) with no bony erosion. The patient underwent complete surgical excision under general anesthesia. The lesion was excised in toto via an intraoral approach, revealing a well-encapsulated, gelatinous mass. Histopathological examination confirmed the diagnosis of angiomyxoma, showing spindle cells in a myxoid stroma with numerous thin-walled vessels. The postoperative course was uneventful, and the child resumed feeding normally. At the 6-month follow-up, there was no evidence of recurrence, and both functional and cosmetic outcomes were excellent. This case underscores that angiomyxoma, though rare, should be considered in the differential diagnosis of pediatric palatal masses. A combination of cross-sectional imaging and complete surgical excision is the cornerstone of management, leading to a favorable prognosis with low recurrence risk.<\/jats:p>","DOI":"10.4103\/aam.aam_753_25","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:00:10Z","timestamp":1777388410000},"page":"S309-S312","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Early Surgical Intervention in an Infant with Angiomyxoma: Ensuring Complete Excision and Prevention of Recurrence"],"prefix":"10.4103","volume":"25","author":[{"given":"Jovitha Maria","family":"Jacob","sequence":"first","affiliation":[{"name":"Department of ENT, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akarsh","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of ENT, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aishwarya","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of ENT, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayur","family":"Ingale","sequence":"additional","affiliation":[{"name":"Department of ENT, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod","family":"Shinde","sequence":"additional","affiliation":[{"name":"Department of ENT, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manu S.","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of ENT, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"R1-20260916","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/00000478-198807000-00003","article-title":"Superficial angiomyxomas with and without epithelial components. Report of 30 tumors in 28 patients","volume":"12","author":"Allen","year":"1988","journal-title":"Am J Surg Pathol"},{"key":"R2-20260916","doi-asserted-by":"crossref","first-page":"503","DOI":"10.21873\/invivo.13107","article-title":"Superficial angiomyxoma of the wrist: Case report and literature review","volume":"37","author":"Chijiiwa","year":"2023","journal-title":"In Vivo"},{"key":"R3-20260916","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.humpath.2021.12.003","article-title":"A clinicopathologic analysis of 54 cases of cutaneous myxoma","volume":"120","author":"Sharma","year":"2022","journal-title":"Hum Pathol"},{"key":"R4-20260916","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1097\/PAS.0000000000001851","article-title":"Superficial angiomyxomas frequently demonstrate loss of protein kinase a regulatory subunit 1 alpha expression: immunohistochemical analysis of 29 cases and cutaneous myxoid neoplasms with histopathologic overlap","volume":"46","author":"Neumann","year":"2022","journal-title":"Am J Surg Pathol"},{"key":"R5-20260916","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1097\/00000478-199908000-00008","article-title":"Superficial angiomyxoma: Clinicopathologic analysis of a series of distinctive but poorly recognized cutaneous tumors with tendency for recurrence","volume":"23","author":"Calonje","year":"1999","journal-title":"Am J Surg Pathol"},{"key":"R6-20260916","doi-asserted-by":"crossref","first-page":"69","DOI":"10.2334\/josnusd.22-0334","article-title":"A rare case of solitary intraoral superficial angiomyxoma arising in the soft palate","volume":"65","author":"Hirai","year":"2023","journal-title":"J Oral Sci"},{"key":"R7-20260916","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1007\/s12105-022-01447-4","article-title":"Rapidly growing superficial angiomyxoma in mandibular gingiva: A case report and literature review","volume":"16","author":"Morimoto","year":"2022","journal-title":"Head Neck Pathol"},{"key":"R8-20260916","doi-asserted-by":"crossref","first-page":"116","DOI":"10.4103\/njms.NJMS_116_20","article-title":"Transoral robotic surgery for angiomyxoma of upper alveolus","volume":"12","author":"Nair","year":"2021","journal-title":"Natl J Maxillofac Surg"},{"key":"R9-20260916","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1097\/00004347-199710000-00006","article-title":"Superficial angiomyxoma (cutaneous myxoma): A clinicopathologic study of 17 cases arising in the genital region","volume":"16","author":"Fetsch","year":"1997","journal-title":"Int J Gynecol Pathol"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_753_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T12:00:49Z","timestamp":1789560049000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_753_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,28]]},"references-count":9,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_753_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,28]]},"assertion":[{"value":"2025-11-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}