{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:46:45Z","timestamp":1791812805231,"version":"4.3.4"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This case series highlights three young patients who presented with thoracic malignancies typically seen in older adults. The first case involved metastatic soft tissue sarcoma in a young male in his twenties, the second was a young female in her late thirties diagnosed with adenocarcinoma of the lung after prolonged fever, and the third was a young male in his early twenties with metastatic osteogenic sarcoma presenting as chest pain and respiratory distress. These cases emphasize the need for heightened clinical suspicion and early diagnostic evaluation of malignancies in young individuals, even in the absence of traditional risk factors, to enable timely and appropriate management.<\/jats:p>","DOI":"10.4103\/aam.aam_755_25","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:00:18Z","timestamp":1777388418000},"page":"S480-S483","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic Surprises: Thoracic Malignancies with Atypical Features in Young Adults"],"prefix":"10.4103","volume":"25","author":[{"given":"Hemant","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneeket","family":"Rastogi","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Singhal","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, TS Misra Medical College, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagar","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"R2-20261012","doi-asserted-by":"crossref","first-page":"e432488","DOI":"10.1200\/EDBK_432488","article-title":"Tackling non-small cell lung cancer in young adults: From risk factors and genetic susceptibility to lung cancer profile and outcomes","volume":"44","author":"Laguna","year":"2024","journal-title":"Am Soc Clin Oncol Educ Book"},{"key":"R3-20261012","doi-asserted-by":"crossref","first-page":"e166","DOI":"10.1016\/S1470-2045(17)30099-2","article-title":"Soft tissue sarcomas in adolescents and young adults: A comparison with their paediatric and adult counterparts","volume":"18","author":"van der Graaf","year":"2017","journal-title":"Lancet Oncol"},{"key":"R4-20261012","doi-asserted-by":"crossref","first-page":"15330338211066240","DOI":"10.1177\/15330338211066240","article-title":"Score for the risk and overall survival of lung metastasis in patients first diagnosed with soft tissue sarcoma: A novel nomogram-based risk assessment system","volume":"21","author":"Fan","year":"2022","journal-title":"Technol Cancer Res Treat"},{"key":"R5-20261012","first-page":"6502","article-title":"Osteosarcoma in patients below 25 years of age: An observational study of incidence, metastasis, treatment and outcomes","volume":"16","author":"Nie","year":"2018","journal-title":"Oncol Lett"},{"key":"R6-20261012","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1186\/s12885-023-11024-9","article-title":"Incidence, survival, and associated factors estimation in osteosarcoma patients with lung metastasis: A single-center experience of 11 years in Tianjin, China","volume":"23","author":"Zhang","year":"2023","journal-title":"BMC Cancer"},{"key":"R7-20261012","doi-asserted-by":"crossref","first-page":"e518","DOI":"10.1016\/j.ijid.2009.06.009","article-title":"Non-small cell lung cancer presenting with neoplastic fever at diagnosis and relapse","volume":"14","author":"Zee","year":"2010","journal-title":"Int J Infect Dis"},{"key":"R8-20261012","doi-asserted-by":"crossref","first-page":"e15840","DOI":"10.1097\/MD.0000000000015840","article-title":"Naproxen for the treatment of neoplastic fever: A PRISMA-compliant systematic review and meta-analysis","volume":"98","author":"Zhang","year":"2019","journal-title":"Medicine (Baltimore)"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_755_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:01:27Z","timestamp":1791810087000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_755_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,28]]},"references-count":7,"journal-issue":{"issue":"Suppl 3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_755_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,28]]},"assertion":[{"value":"2025-11-22","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}