{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:37:21Z","timestamp":1790833041802,"version":"4.1.0"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:00:00Z","timestamp":1776297600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the upper limb. Although many cases are idiopathic, structural or inflammatory pathology of the flexor tendon sheath can result in secondary median nerve compression. Diabetes mellitus predisposes to such changes due to chronic connective tissue alterations, but secondary CTS arising solely from noninfective flexor tenosynovitis remains uncommon. A 49-year-old woman with recently diagnosed type 2 diabetes presented with a 2-month history of progressive right-wrist pain, paresthesia, and volar swelling. Magnetic resonance imaging revealed marked tenosynovitis of the finger flexors with palmar bowing of the flexor retinaculum and associated median nerve edema, whereas nerve conduction studies confirmed compressive neuropathy. Conservative therapy failed, and open carpal tunnel release was performed, yielding immediate symptom relief and improved hand function at 6-week follow-up. Secondary CTS due to chronic flexor tenosynovitis should be suspected in diabetic patients with refractory symptoms. Early multimodal evaluation and timely decompression may prevent irreversible neuropathy.<\/jats:p>","DOI":"10.4103\/aam.aam_796_25","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T07:00:22Z","timestamp":1776409222000},"page":"S233-S235","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Secondary Carpal Tunnel Syndrome Due to Flexor Tenosynovitis in a Diabetic Patient"],"prefix":"10.4103","volume":"25","author":[{"given":"Pankaj","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Orthopedics, D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Kale","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dheerajkumar","family":"Jadhav","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,16]]},"reference":[{"key":"R1-20260819","first-page":"e7333","article-title":"Carpal tunnel syndrome: A review of literature","volume":"12","author":"Genova","year":"2020","journal-title":"Cureus"},{"key":"R2-20260819","doi-asserted-by":"crossref","first-page":"69","DOI":"10.2174\/1874325001206010069","article-title":"Carpal tunnel syndrome: A review of the recent literature","volume":"6","author":"Ibrahim","year":"2012","journal-title":"Open Orthop J"},{"key":"R4-20260819","doi-asserted-by":"crossref","first-page":"20503121231218889","DOI":"10.1177\/20503121231218889","article-title":"Ultrasound and magnetic resonance imaging neurography assessment of diagnostic criteria in patients with carpal tunnel syndrome using electrophysiological tests as gold standard: A prospective study","volume":"12","author":"Alkaphoury","year":"2024","journal-title":"SAGE Open Med"},{"key":"R5-20260819","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0266-7681_87_90020-9","article-title":"Pathology of the flexor tendon sheath in the spontaneous carpal tunnel syndrome","volume":"12","author":"Neal","year":"1987","journal-title":"J Hand Surg Br"},{"key":"R6-20260819","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1177\/1558944719855442","article-title":"The sensitivity and specificity of nerve conduction studies for diagnosis of carpal tunnel syndrome: A systematic review","volume":"16","author":"Demino","year":"2021","journal-title":"Hand (N Y)"},{"key":"R7-20260819","doi-asserted-by":"crossref","first-page":"4","DOI":"10.17712\/1658-3183.2112","article-title":"Pathophysiology of carpal tunnel syndrome","volume":"20","author":"Aboonq","year":"2015","journal-title":"Neurosciences (Riyadh)"},{"key":"R8-20260819","doi-asserted-by":"crossref","first-page":"347","DOI":"10.4236\/ss.2025.166036","article-title":"Surgical management of carpal tunnel syndrome refractory to conservative treatment: A comparative analysis of open versus endoscopic carpal tunnel release","volume":"16","author":"Yoo","year":"2025","journal-title":"Surg Sci"},{"key":"R9-20260819","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1142\/S1013702518500087","article-title":"Effectiveness of surgical versus conservative treatment for carpal tunnel syndrome: A systematic review, meta-analysis and qualitative analysis","volume":"38","author":"Klokkari","year":"2018","journal-title":"Hong Kong Physiother J"},{"key":"R10-20260819","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1142\/S2424835521500454","article-title":"Flexor synovectomy as an adjunct to carpal tunnel release in primary carpal tunnel syndrome: A meta-analysis","volume":"26","author":"Chiang","year":"2021","journal-title":"J Hand Surg Asian Pac Vol"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_796_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T12:01:52Z","timestamp":1787140912000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_796_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,16]]},"references-count":9,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_796_25","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,16]]},"assertion":[{"value":"2025-12-05","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}