{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T12:29:29Z","timestamp":1793795369578,"version":"4.6.1"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Lung adenocarcinoma may occasionally present with radiological features that closely mimic pulmonary infection, leading to diagnostic delay. We report the case of a 63-year-old nonsmoking woman who presented with chronic cough, low-grade fever, progressive weight loss, and worsening breathlessness. Computed tomography of the thorax demonstrated bilateral peribronchial nodules and multifocal consolidations with air bronchograms, initially raising suspicion for pulmonary tuberculosis and subsequently fungal infection. Despite prolonged antimicrobial therapy, her symptoms persisted. Extensive microbiological and autoimmune evaluation was unrevealing. Flexible bronchoscopy with bronchoalveolar lavage and transbronchial lung biopsy established the diagnosis of lung adenocarcinoma, with immunohistochemistry positive for thyroid transcription factor-1 and molecular testing revealing an EGFR exon 19 deletion. Treatment with osimertinib resulted in marked clinical and radiological improvement. This case highlights the importance of considering lung adenocarcinoma in patients with bilateral nonresolving pneumonia and emphasizes the value of obtaining tissue diagnosis when conventional treatment fails.<\/jats:p>","DOI":"10.4103\/aam.aam_799_26","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:00:14Z","timestamp":1790402414000},"page":"S935-S937","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Lung Adenocarcinoma Presenting as Bilateral Nonresolving Pneumonia Mimicking Pulmonary Infection"],"prefix":"10.4103","volume":"25","author":[{"given":"John","family":"Muchahary","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine, Manipal Hospital, Panaji, Goa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brizellda","family":"Dcunha","sequence":"additional","affiliation":[{"name":"Department of Pathology, Manipal Hospital, Panaji, Goa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gargi","family":"Kadkade","sequence":"additional","affiliation":[{"name":"Department of Radiology, Manipal Hospital, Panaji, Goa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradnya Neelakanta","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Pathology, Manipal Hospital, Panaji, Goa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"R1-20261104","doi-asserted-by":"crossref","first-page":"8661","DOI":"10.3390\/ijms22168661","article-title":"Current and future development in lung cancer diagnosis","volume":"22","author":"Nooreldeen","year":"2021","journal-title":"Int J Mol Sci"},{"key":"R2-20261104","doi-asserted-by":"crossref","first-page":"731","DOI":"10.21037\/jtd-22-1199","article-title":"Lung cancer with air lucency: A systematic review and clinical management guide","volume":"15","author":"Detterbeck","year":"2023","journal-title":"J Thorac Dis"},{"key":"R3-20261104","first-page":"329","article-title":"Advanced pneumonic-type lung carcinoma: A retrospective study of clinical-radiological-pathological characteristics with survival analysis in a single Chinese hospital","volume":"22","author":"Liu","year":"2019","journal-title":"Zhongguo Fei Ai Za Zhi"},{"key":"R4-20261104","first-page":"150","article-title":"Diffuse pulmonary infiltrates: A guise of adenocarcinoma","volume":"22","author":"Ismail","year":"2017","journal-title":"Respir Med Case Rep"},{"key":"R5-20261104","doi-asserted-by":"crossref","first-page":"110899","DOI":"10.1016\/j.ijscr.2025.110899","article-title":"A rare presentation of primary lung adenocarcinoma mimicking bilateral interstitial infiltration: A case report and literature review","volume":"127","author":"Abed","year":"2025","journal-title":"Int J Surg Case Rep"},{"key":"R6-20261104","first-page":"005790","article-title":"The great mimicker: Pulmonary adenocarcinoma with interstitial lung disease-like presentation","volume":"12","author":"Upadhyay","year":"2025","journal-title":"Eur J Case Rep Intern Med"},{"key":"R7-20261104","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1183\/09031936.04.00124703","article-title":"Adenocarcinoma of the lung mimicking inflammatory lung disease with honeycombing","volume":"24","author":"Lantuejoul","year":"2004","journal-title":"Eur Respir J"}],"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_799_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T12:04:54Z","timestamp":1793793894000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_799_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":7,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/aam.aam_799_26","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,25]]},"assertion":[{"value":"2026-06-14","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-17","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}