{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T13:34:29Z","timestamp":1787578469265,"version":"build-2736575974"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n Background:<\/jats:title>\n Ultrasound-guided supra-inguinal fascia iliaca compartment block (FICB) is increasingly used for postoperative analgesia in femur fracture surgery. However, evidence comparing different concentrations of bupivacaine for this block remains limited.<\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n The objective of this study is to compare the analgesic efficacy and safety of 0.25% and 0.125% bupivacaine administered through ultrasound-guided supra-inguinal FICB in patients undergoing femur fracture surgery.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n In this prospective, randomized, double-blind controlled trial, 90 American Society of Anesthesiologists I\u2013II patients aged 18\u201350 years undergoing elective femur fracture fixation under spinal anesthesia were enrolled. Patients were randomized into two groups: Group A (\n n<\/jats:italic>\n = 45) received 20 mL of 0.25% bupivacaine and Group B (\n n<\/jats:italic>\n = 45) received 20 mL of 0.125% bupivacaine for ultrasound-guided supra-inguinal FICB. Postoperative pain scores, rescue analgesic requirements, hemodynamic parameters, sensory blockade, ambulation, and adverse events were assessed.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Baseline characteristics were comparable between the groups. Visual Analog Scale scores at rest and during movement 20 min after block administration were significantly lower in Group A (\n P<\/jats:italic>\n < 0.001). Postoperative pain scores remained significantly lower in Group A at 2, 4, 6, and 18 h. Patients receiving 0.25% bupivacaine had significantly greater sensory blockade, lower total rescue analgesic consumption, earlier time to first rescue analgesia, and more stable hemodynamic parameters than those receiving 0.125% bupivacaine (\n P<\/jats:italic>\n < 0.05). No major complications or adverse effects were observed in either group.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Ultrasound-guided suprainguinal FICB is an effective and safe technique for postoperative analgesia in femur fracture surgery. Compared with 0.125% bupivacaine, 0.25% bupivacaine provided superior analgesia, prolonged pain relief, reduced analgesic requirements, and better hemodynamic stability.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/aam.aam_835_26","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T13:10:04Z","timestamp":1787577004000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Ultrasound-guided Suprainguinal Fascia Iliaca Block for Postoperative Analgesia in Patients Undergoing Femur Fracture Surgery: A Randomized Control Trial Study Comparing Bupivacaine (0.25%) and Bupivacaine (0.125%)"],"prefix":"10.4103","author":[{"given":"Shadab","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sourabh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekramul","family":"Haque","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishwanath","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shio","family":"Priye","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,8,25]]},"container-title":["Annals of African Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_835_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T13:10:05Z","timestamp":1787577005000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/aam.aam_835_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,25]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4103\/aam.aam_835_26","relation":{},"ISSN":["1596-3519","0975-5764"],"issn-type":[{"value":"1596-3519","type":"print"},{"value":"0975-5764","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,25]]},"assertion":[{"value":"2026-06-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}